GCK gene-body hypomethylation is associated with the risk of coronary heart disease

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Xu, Limin ^a   Zheng, Dawei ^a   Wang, Lingyan ^b   Jiang, Danjie ^a   Liu, Haibo ^a   Xu, Leiting ^a   Liao, Qi ^a   Zhang, Lina ^a   Liu, Panpan ^a   Shi, Xinbao ^a   Wang, Zhaoyang ^a   Sun, Lebo ^a   Zhou, Qingyun ^a   Li, Ni ^a   Huang, Yi ^a   Le, Yanping ^a   Ye, Meng ^a   Shao, Guofeng ^a   Duan, Shiwei ^a  

^a NINGBO UNIVERSITY   (China)

^b NINGBO NO 2 HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; APOLIPOPROTEIN B; BISULFITE; GAMMA GLUTAMYLTRANSFERASE; GLUCOKINASE; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ARTICLE; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EXON; FEMALE; GENETIC ASSOCIATION; HUMAN; INTRON; ISCHEMIC HEART DISEASE; MALE; PYROSEQUENCING; RISK ASSESSMENT; SEX DIFFERENCE; CASE CONTROL STUDY; CORONARY ARTERY DISEASE; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETICS; RISK FACTOR;

CASE-CONTROL STUDIES; CORONARY DISEASE; CPG ISLANDS; DNA METHYLATION; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GLUCOKINASE; HUMANS; MALE; RISK FACTORS;

EID: 84896112404     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/151723     Document Type: Article

References (45)

1. Currie C. J., Morgan C. L., Peters J. R., Patterns and costs of hospital care for coronary heart disease related and not related to diabetes. Heart 1997 78 6 544 549 2-s2.0-0031452906 (Pubitemid 28034201)
2. Eriksson M., Carlberg B., Eliasson M., The disparity in long-term survival after a first stroke in patients with and without diabetes persists: the northern sweden monica study. Cerebrovascular Diseases 2012 34 153 160
3. Neufeld H. N., Goldbourt U., Coronary heart disease: genetic aspects. Circulation 1983 67 5 943 954 2-s2.0-0020622276 (Pubitemid 13080469)
4. Roger V. L., Go A. S., Lloyd-Jones D. M., Heart disease and stroke statistics-2011 update: a report from the American Heart Association. Circulation 2011 123 e18 e209
5. Hara M., Sakata Y., Sato H., [genetic factors in myocardial infarction]. The Japanese Journal of Clinical Pathology 2013 61 176 183
6. Pan M. H., Lai C. S., Wu J. C., Ho C. T., Epigenetic and diseases targets by polyphenols. Current Pharmaceutical Design 2013 19 6156 6185
7. Drong A. W., Lindgren C. M., McCarthy M. I., The genetic and epigenetic basis of type 2 diabetes and obesity. Clinical Pharmacology and Therapeutics 2012 92 707 715
8. Dayeh T. A., Olsson A. H., Volkov P., Almgren P., Ronn T., Ling C., Identification of cpg-snps associated with type 2 diabetes and differential DNA methylation in human pancreatic islets. Diabetologia 2013 56 1036 1046
9. Gardiner-Garden M., Frommer M., CpG islands in vertebrate genomes. Journal of Molecular Biology 1987 196 2 261 282 2-s2.0-0023216891 (Pubitemid 17122132)
10. Klose R. J., Bird A. P., Genomic DNA methylation: the mark and its mediators. Trends in Biochemical Sciences 2006 31 2 89 97 2-s2.0-32344450824 10.1016/j.tibs.2005.12.008 (Pubitemid 43221841)
11. Jones P. A., Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nature Reviews Genetics 2012 13 484 492
12. Aran D., Toperoff G., Rosenberg M., Hellman A., Replication timing-related and gene body-specific methylation of active human genes. Human Molecular Genetics 2011 20 4 670 680 2-s2.0-78751693154 10.1093/hmg/ddq513
13. Jjingo D., Conley A. B., Yi S. V., Lunyak V. V., Jordan I. K., On the presence and role of human gene-body DNA methylation. Oncotarget 2012 3 462 474
14. Ball M. P., Li J. B., Gao Y., Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nature Biotechnology 2009 27 361 368
15. Illingworth R. S., Gruenewald-Schneider U., Webb S., Kerr A. R. W., James K. D., Turner D. J., Smith C., Harrison D. J., Andrews R., Bird A. P., Orphan CpG Islands Identify numerous conserved promoters in the mammalian genome. PLoS Genetics 2010 6 9 2-s2.0-78049419464 10.1371/journal.pgen.1001134 e1001134
16. Iynedjian P. B., Molecular physiology of mammalian glucokinase. Cellular and Molecular Life Sciences 2009 66 1 27 42 2-s2.0-58149525327 10.1007/s00018-008-8322-9
17. Heredia V. V., Thomson J., Nettleton D., Sun S., Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis. Biochemistry 2006 45 24 7553 7562 2-s2.0-33745150728 10.1021/bi060253q (Pubitemid 43894948)
18. Kamata K., Mitsuya M., Nishimura T., Eiki J.-I., Nagata Y., Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase. Structure 2004 12 3 429 438 2-s2.0-1542791635 10.1016/j.str.2004. 02.005 (Pubitemid 38353064)
19. Coutinho M., Gerstein H. C., Wang Y., Yusuf S., The relationship between glucose and incident cardiovascular events: A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years. Diabetes Care 1999 22 2 233 240 2-s2.0-0032902850 10.2337/diacare.22.2.233 (Pubitemid 29056916)
20. Rose C. S., Ek J., Urhammer S. A., Glümer C., Borch-Johnsen K., Jørgensen T., Pedersen O., Hansen T., A -30G>A polymorphism of the β -cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites. Diabetes 2005 54 10 3026 3031 2-s2.0-25844513867 10.2337/diabetes.54.10.3026 (Pubitemid 41401103)
21. Fu D., Cong X., Ma Y., Genetic polymorphism of glucokinase on the risk of type 2 diabetes and impaired glucose regulation: evidence based on 298, 468 subjects. PloS ONE 2013 8 e55727
22. Van Schaftingen E., Detheux M., da Cunha M. V., Short-term control of glucokinase activity: role of a regulatory protein. The FASEB Journal 1994 8 6 414 419 2-s2.0-0028338590 (Pubitemid 24155954)
23. Matschinsky F. M., Glaser B., Magnuson M. A., Pancreatic β -cell glucokinase: closing the gap between theoretical concepts and experimental realities. Diabetes 1998 47 3 307 315 2-s2.0-0031892853 10.2337/diabetes.47.3. 307 (Pubitemid 28104189)
24. Cauchi S., Ezzidi I., El Achhab Y., Mtiraoui N., Chaieb L., Salah D., Nejjari C., Labrune Y., Yengo L., Beury D., Vaxillaire M., Mahjoub T., Chikri M., Froguel P., European genetic variants associated with type 2 diabetes in North African Arabs. Diabetes & Metabolism 2012 38 4 316 323 2-s2.0-84858974639 10.1016/j.diabet.2012.02.003
25. Sotos-Prieto M., Guillen M., Vicente Sorli J., Relevant associations of the glucokinase regulatory protein/glucokinase gene variation with tag concentrations in a high-cardiovascular risk population: modulation by the mediterranean diet. The British Journal of Nutrition 2013 109 193 201
26. Webster R. J., Warrington N. M., Weedon M. N., Hattersley A. T., McCaskie P. A., Beilby J. P., Palmer L. J., Frayling T. M., The association of common genetic variants in the APOA5, LPL and GCK genes with longitudinal changes in metabolic and cardiovascular traits. Diabetologia 2009 52 1 106 114 2-s2.0-57249113728 10.1007/s00125-008-1175-9
27. März W., Nauck M., Hoffmann M. M., Nagel D., Boehm B. O., Koenig W., Rothenbacher D., Winkelmann B. R., G(-30)A polymorphism in the pancreatic promoter of the glucokinase gene associated with angiographic coronary artery disease and type 2 diabetes mellitus. Circulation 2004 109 23 2844 2849 2-s2.0-2942694341 10.1161/01.CIR.0000129306.44085.C4 (Pubitemid 38780297)
28. Jiang M. H., Fei J., Lan M. S., Lu Z. P., Liu M., Fan W. W., Gao X., Lu D. R., Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential. Diabetologia 2008 51 8 1525 1533 2-s2.0-48149092462 10.1007/s00125-008-1034-8
29. Zhou J., Huang Y., Huang R. S., A case-control study provides evidence of association for a common snp rs974819 in pdgfd to coronary heart disease and suggests a sex-dependent effect. Thrombosis Research 2012 130 602 606
30. Jiang D., Zheng D., Wang L., Elevated pla2g7 gene promoter methylation as a gender-specific marker of aging increases the risk of coronary heart disease in females. PloS ONE 2013 8 e59752
31. Haffner S. M., Lehto S., Rönnemaa T., Pyörälä K., Laakso M., Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. The New England Journal of Medicine 1998 339 4 229 234 2-s2.0-0032560807 10.1056/NEJM199807233390404 (Pubitemid 28350165)
32. Suzuki M. M., Bird A., DNA methylation landscapes: provocative insights from epigenomics. Nature Reviews Genetics 2008 9 6 465 476 2-s2.0-43749098985 10.1038/nrg2341 (Pubitemid 351693975)
33. Papait R., Greco C., Kunderfranco P., Latronico M. V., Condorelli G., Epigenetics: a new mechanism of regulation of heart failure? Basic Research in Cardiology 2013 108 361
34. Movassagh M., Choy M.-K., Knowles D. A., Cordeddu L., Haider S., Down T., Siggens L., Vujic A., Simeoni I., Penkett C., Goddard M., Lio P., Bennett M. R., Foo R. S.-Y., Distinct epigenomic features in end-stage failing human hearts. Circulation 2011 124 22 2411 2422 2-s2.0-82355180985 10.1161/CIRCULATIONAHA.111.040071
35. Maunakea A. K., Nagarajan R. P., Bilenky M., Ballinger T. J., Dsouza C., Fouse S. D., Johnson B. E., Hong C., Nielsen C., Zhao Y., Turecki G., Delaney A., Varhol R., Thiessen N., Shchors K., Heine V. M., Rowitch D. H., Xing X., Fiore C., Schillebeeckx M., Jones S. J. M., Haussler D., Marra M. A., Hirst M., Wang T., Costello J. F., Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature 2010 466 7303 253 257 2-s2.0-77954504873 10.1038/nature09165
36. Zhang X., Yazaki J., Sundaresan A., Cokus S., Chan S. W.-L., Chen H., Henderson I. R., Shinn P., Pellegrini M., Jacobsen S. E., Ecker J., Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsis. Cell 2006 126 6 1189 1201 2-s2.0-33748629119 10.1016/j.cell.2006. 08.003 (Pubitemid 44380289)
37. Zilberman D., Gehring M., Tran R. K., Ballinger T., Henikoff S., Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription. Nature Genetics 2007 39 1 61 69 2-s2.0-33845880624 10.1038/ng1929 (Pubitemid 46026502)
38. Hoekenga O. A., Muszynski M. G., Cone K. C., Developmental patterns of chromatin structure and DNA methylation responsible for epigenetic expression of a maize regulatory gene. Genetics 2000 155 4 1889 1902 2-s2.0-0033886117 (Pubitemid 30626405)
39. Bogdarina I., Murphy H. C., Burns S. P., Clark A. J. L., Investigation of the role of epigenetic modification of the rat glucokinase gene in fetal programming. Life Sciences 2004 74 11 1407 1415 2-s2.0-0347990383 10.1016/j.lfs.2003.08.017 (Pubitemid 38045533)
40. Jiang M., Zhang Y., Liu M., Lan M. S., Fei J., Fan W., Gao X., Lu D., Hypermethylation of hepatic glucokinase and L-type pyruvate kinase promoters in high-fat diet-induced obese rats. Endocrinology 2011 152 4 1284 1289 2-s2.0-79953197543 10.1210/en.2010-1162
41. Raddatz G., Hagemann S., Aran D., Aging is associated with highly defined epigenetic changes in the human epidermis. Epigenetics & Chromatin 2013 6, article 36
42. Christensen B. C., Houseman E. A., Marsit C. J., Zheng S., Wrensch M. R., Wiemels J. L., Nelson H. H., Karagas M. R., Padbury J. F., Bueno R., Sugarbaker D. J., Yeh R.-F., Wiencke J. K., Kelsey K. T., Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CPG island context. PLoS Genetics 2009 5 8 2-s2.0-70149099610 10.1371/journal.pgen.1000602 e1000602
43. Winnefeld M., Lyko F., The aging epigenome: DNA methylation from the cradle to the grave. Genome Biology 2012 13 165
44. Fraga M. F., Ballestar E., Paz M. F., Ropero S., Setien F., Ballestar M. L., Heine-Suñer D., Cigudosa J. C., Urioste M., Benitez J., Boix-Chornet M., Sanchez-Aguilera A., Ling C., Carlsson E., Poulsen P., Vaag A., Stephan Z., Spector T. D., Wu Y.-Z., Plass C., Esteller M., Epigenetic differences arise during the lifetime of monozygotic twins. Proceedings of the National Academy of Sciences of the United States of America 2005 102 30 10604 10609 2-s2.0-23044514669 10.1073/pnas.0500398102 (Pubitemid 41061601)
45. Grönniger E., Weber B., Heil O., Peters N., Stäb F., Wenck H., Korn B., Winnefeld M., Lyko F., Aging and chronic sun exposure cause distinct epigenetic changes in human skin. PLoS Genetics 2010 6 5 e1000971 2-s2.0-77956639883 10.1371/journal.pgen.1000971