Expression of human apolipoprotein E4 reduces insulin-receptor substrate 1 expression and Akt phosphorylation in the ageing liver

FEBS Open Bio

Volumn 4, Issue , 2014, Pages 260-265

  Ong, Qi Rui ^a   Chan, Elizabeth S ^a   Lim, Mei Li ^a   Wong, Boon Seng ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Ageing; Akt signaling; ApoE; Liver insulin signaling

Indexed keywords

APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P110; PROTEIN P85;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; GLUCOSE TOLERANCE; LIPID DIET; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 84896105813     PISSN: 22115463     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fob.2014.02.011     Document Type: Article

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