Short-term resveratrol exposure causes In Vitro and In Vivo growth inhibition and apoptosis of bladder cancer cells

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Wu, Mo Li ^a   Li, Hong ^a   Yu, Li Jun ^a   Chen, Xiao Yan ^a   Kong, Qing You ^a   Song, Xue ^a   Shu, Xiao Hong ^a   Liu, Jia ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; JANUS KINASE 2; MITOMYCIN; MYC PROTEIN; PROTEIN P53; RESVERATROL; SIRTUIN 1; STAT3 PROTEIN; SURVIVIN; VASCULOTROPIN; ALPHA-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE; PRIMER DNA; STAT3 PROTEIN, MOUSE; STILBENE DERIVATIVE; TYRPHOSTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG SAFETY; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; S PHASE CELL CYCLE CHECKPOINT; SHORT COURSE THERAPY; TOXICITY TESTING; TRANSITIONAL CELL CARCINOMA; ACTIVE TRANSPORT; ANALYSIS OF VARIANCE; ANIMAL; CARCINOMA, TRANSITIONAL CELL; CELL PROLIFERATION; DOSE RESPONSE; DRUG EFFECTS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; NUDE MOUSE; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; URINARY BLADDER NEOPLASMS; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, TRANSITIONAL CELL; CELL LINE, TUMOR; CELL PROLIFERATION; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, NUDE; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; S PHASE CELL CYCLE CHECKPOINTS; STAT3 TRANSCRIPTION FACTOR; STILBENES; TYRPHOSTINS; URINARY BLADDER NEOPLASMS;

EID: 84896105051     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089806     Document Type: Article

References (36)

1. Cheung G, Sahai A, Billlia M, Dasgupta P, Khan MS (2013) Recent advances in the diagnosis and treatment of bladder cancer. BMC Med 11: 13.
2. Houghton BB, Chalasani V, Hayne D, Grimison P, Brown CS, et al. (2013) Intravesical chemotherapy plus bacille Calmette-Guérin in non-muscle invasive bladder cancer: a systematic review with meta-analysis. BJU Int 111: 977-983.
3. Pinto-Leite R, Arantes-Rodrigues R, Palmeira C, Colaço B, Lopes C, et al. (2013) Everolimus combined with cisplatin has a potential role in treatment of urothelial bladder cancer. Biomed Pharmacother 67: 116-121.
4. Barlow LJ, Benson MC (2013) Experience with newer intravesical chemotherapy for high-risk non-muscle-invasive bladder cancer. Curr Urol Rep 14: 65-70.
5. Chen HJ, Hsu LS, Shia YT, Lin MW, Lin CM (2012) The β-catenin/TCF complex as a novel target of resveratrol in the Wnt/β-catenin signaling pathway. Biochem Pharmacol 84: 1143-1153.
6. Yaseen A, Chen S, Hock S, Rosato R, Dent P, et al. (2012) Resveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathway. Mol Pharmacol 82: 1030-1041.
7. Leon-Galicia I, Diaz-Chavez J, Garcia-Villa E, Uribe-Figueroa L, Hidalgo-Miranda A, et al. (2013) Resveratrol induces downregulation of DNA repair genes in MCF-7 human breast cancer cells. Eur J Cancer Prev 22: 11-20.
8. Wen S, Li H, Wu ML, Fan SH, Wang Q, et al. (2011) Inhibition of NF-κB signaling commits resveratrol-treated medulloblastoma cells to apoptosis without neuronal differentiation. J Neuro-oncol 104: 169-177.
9. Bai Y, Mao QQ, Qin J, Zheng XY, Wang YB, et al. (2010) Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo. Cancer Sci 101: 488-493.
10. Lin X, Wu G, Huo WQ, Zhang Y, Jin FS (2012) Resveratrol induces apoptosis associated with mitochondrial dysfunction in bladder carcinoma cells. Int J Urol 19: 757-764.
11. Stocco B, Toledo K, Salvador M, Paulo M, Koyama N, et al. (2012) Dose-dependent effect of resveratrol on bladder cancer cells: chemoprevention and oxidative stress. Maturitas 72: 72-78.
12. García Mediero JM, Ferruelo Alonso A, Páez Borda A, Luján Galán M, Angulo Cuesta J, et al. (2005) Effect of polyphenols from the Mediterranean diet on proliferation and mediators of in vitro invasiveness of the MB-49 murine bladder cancer cell line. Actas Urol Esp 29: 743-749.
13. Parada LF, Tabin CJ, Shih C, Weinberg RA (1982). Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene. Nature 297: 474-478. (Pubitemid 12007526)
14. Liu J, Wang Q, Wang X, Sun Y, Chen XY, et al. (2003) Apoptosis of bladder cancer cells induced by short-term and low-dose Mitomycin-C: potential molecular mechanism and clinical implication. Int J Mol Med 11: 389-394.
15. Colombo R, Rocchini L, Suardi N, Benigni F, Colciago G, et al. (2012) Neoadjuvant short-term intensive intravesical mitomycin C regimen compared with weekly schedule for low-grade recurrent non-muscle-invasive bladder cancer: preliminary results of a randomised phase 2 study. Eur Urol 62: 797-802.
16. Gibbs CP, Kukekov VG, Reith JD, Tchigrinova O, Suslov ON, et al. (2005) Stem-like cells in bone sarcomas: implications for tumorigenesis. Neoplasia 7: 967-976.
17. Ikeguchi M, Kaibara N (2001) Changes in survivin messenger RNA level during cisplatin treatment in gastric cancer. Int J Mol Med 8: 661-666.
18. Grotzer MA, Hogarty MD, Janss AJ, Liu X, Zhao H, et al. (2001) MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma. Clin Cancer Res 7: 2425-2433. (Pubitemid 32751645)
19. Simile MM, De Miglio MR, Muroni MR, Frau M, Asara G, et al. (2004) Downregulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells. Carcinogenesis 25: 333-341. (Pubitemid 38344399)
20. Yu LJ, Wu ML, Li H, Chen XY, Wang Q, et al. (2008) Inhibition of STAT3 expression and signaling in resveratrol-differentiated medulloblastoma cells. Neoplasia 10: 736-744. (Pubitemid 351883890)
21. Cirone M, Di Renzo L, Lotti LV, Conte V, Trivedi P, et al. (2012) Primary effusion lymphoma cell death induced by bortezomib and AG490 activates dendritic cells through CD91. PLoS ONE 7: e31732.
22. Chan E, Patel A, Heston W, Larchian W (2009) Mouse orthotopic models for bladder cancer research. BJU Int 104: 1286-1291.
23. Vachon P, Faubert S, Blais D, Comtois A, Bienvenu JG (2000) A pathophysiological study of abdominal organs following intraperitoneal injections of chloral hydrate in rats: comparison between two anaesthesia protocols. Lab Anim 34: 84-90. (Pubitemid 30060265)
24. Chen C, Zhou H, Liu X, Liu Z, Ma Q (2011) Reduced Expression of von Hippel-Lindau Protein Correlates with Decreased Apoptosis and High Chondrosarcoma Grade. J Bone Joint Surg Am 93: 1833-1840.
25. Hadaschik BA, Adomat H, Fazli L, Fradet Y, Andersen RJ, et al. (2008) Intravesical chemotherapy of high-grade bladder cancer with HTI-286, a synthetic analogue of the marine sponge product hemiasterlin. Clin Cancer Res 14: 1510-1518. (Pubitemid 351413936)
26. Chen CL, Cen L, Kohout J, Hutzen B, Chan C, et al. (2008) Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival. Mol Cancer 7: 78.
27. Chan ES, Patel AR, Hansel DE, Larchian WA, Heston WD (2012) Sunitinib malate provides activity against murine bladder tumor growth and invasion in a preclinical orthotopic model. Urology 80: 736.e1-736.e5.
28. Zou T, Yang Y, Xia F, Huang A, Gao X, et al. (2013) Resveratrol Inhibits CD4+ T cell activation by enhancing the expression and activity of Sirt1. PLoS ONE 8: e75139.
29. Hori YS, Kuno A, Hosoda R, Horio Y (2013) Regulation of FOXOs and p53 by SIRT1 modulators under oxidative stress. PLoS ONE 8: e73875.
30. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, et al. (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127: 2893-2917.
31. Shu XH, Li H, Sun Z, Wu ML, Ma JX, et al. (2010) Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells. Biochem Pharmacol 79: 1516-1525.
32. Shu XH, Li H, Sun XX, Wang Q, Sun Z, et al. (2011) Metabolic patterns and biotransformation activities of resveratrol in human glioblastoma cells: relevance with therapeutic efficacies. PLoS ONE 6: e27484.
33. Abraham P, Isaac B, Ramamoorthy H, Natarajan K (2011) Oral glutamine attenuates cyclophosphamide-induced oxidative stress in the bladder but does not prevent hemorrhagic cystitis in rats. J Med Toxicol 27: 118-124.
34. Quoc Trung L, Espinoza JL, Takami A, Nakao S (2013) Resveratrol induces cell cycle arrest and apoptosis in malignant NK cells via JAK2/STAT3 pathway inhibition. PLoS ONE 8: e55183.
35. Tong C, Morrison A, Mattison S, Qian S, Bryniarski M, et al. (2013) Impaired SIRT1 nucleocytoplasmic shuttling in the senescent heart during ischemic stress. FASEB J 27: 4332-4342.
36. Takwi A, Li Y (2009) The p53 pathway encounters the microRNA world. Curr Genomics 10: 194-197.