Recent advances in the diagnosis and treatment of bladder cancer

BMC Medicine

Volumn 11, Issue 1, 2013, Pages

  Cheung, Grace ^a   Sahai, Arun ^a   Billia, Michele ^a   Dasgupta, Prokar ^a   Khan, Muhammad S ^a  

^a GUY S HOSPITAL   (United Kingdom)

Author keywords

Bladder cancer; Cystoscopy; Narrow band imaging; Photodynamic diagnosis; Radical cystectomy; Urinary markers

Indexed keywords

BCG VACCINE; GEMCITABINE; MITOMYCIN; NUCLEAR MITOTIC APPARATUS PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG;

BLADDER CANCER; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER IMMUNOTHERAPY; CANCER SURVIVAL; CHEMORADIOTHERAPY; CYSTOSCOPY; CYTOLOGY; DISEASE SPECIFIC SURVIVAL; FOLLOW UP; HUMAN; LAPAROSCOPIC SURGERY; MORBIDITY; NARROW BAND IMAGING; NON MUSCLE INVASIVE BLADDER CANCER; OVERALL SURVIVAL; PERIOPERATIVE PERIOD; PHOTODYNAMICS; POINT OF CARE TESTING; REVIEW; ROBOTICS; SENSITIVITY ANALYSIS; URINALYSIS; URINE CYTOLOGY;

CYSTECTOMY; CYTOLOGICAL TECHNIQUES; DRUG THERAPY; ENDOSCOPY; HUMANS; IMMUNOTHERAPY; URINARY BLADDER NEOPLASMS;

EID: 84872268968     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-11-13     Document Type: Review

References (57)

1. Ploeg M, Aben KKH, Kiemeney LA. The present and future burden of urinary bladder cancer in the world. World J Urol 2009, (27:):289-93.
2. Ferlay J, Randi G, Bosetti C, Levi F, Negri E, Boyle P, La Vecchia C. Declining mortality from bladder cancer in Europe. BJU Int 2008, 101:11-9.
3. Jocham D, Stepp H, Waidelich R. Photodynamic diagnosis in urology: State-of-the-art. Eur Urol 2008, 53:1138-48. 10.1016/j.eururo.2007.11.048, 18096307.
4. Yutkin V, Nisman B, Pode D. Can urinary biomarkers replace cystoscopic examination in bladder cancer surveillance?. Expert Rev Anticanc 2010, 10:787-90.
5. Babjuk M, Oosterlinck W, Sylvester R, Kaasinen E, Böhle A, Palou J, Rouprêt M, European Association of Urology (EAU) EAU guidelines on non-muscle-invasive bladder cancer. Uroweb 2012, European Association of Urology (EAU)., http://www.uroweb.org/gls/pdf/05_TaT1_Bladder_Cancer_LR%20March%2013th%202012.pdf
6. Gill IS, Kaouk JH, Meraney AM, Desai MM, Ulchaker JC, Klein EA, Savage SJ, Sung GT. Laparoscopic radical cystectomy and continent orthotopic neobladder performed complete intracorporeally: the initial experience. J Urol 2002, 168:13-8. 10.1016/S0022-5347(05)64821-5, 12050482.
7. Nix J, Smith A, Kurpad R, Nielsen ME, Wallen EM, Pruthi RS. Prospective randomized controlled trial of robotic versus open radical cystectomy for bladder cancer: perioperative and pathologic results. Eur Uro 2010, 57:196-201.
8. James ND, Hussain SA, Hall E, Jenkins P, Tremlett J, Rawlings C, Crundwell M, Sizer B, Sreenivasan T, Hendron C, Lewis R, Waters R, Huddart RA, BC2001 Investigators Radiotherapy with or without chemotherapy in muscle-invasive bladder cancer. N Engl J Med 2012, 366:1477-88. 10.1056/NEJMoa1106106, 22512481, BC2001 Investigators.
9. Epstein JI, Amin MB, Reuter VR, Mostofi FK. The World Health Organization/International Society of Urological Pathology consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder. Am J Surg Pathol 1998, 22:1435-48. 10.1097/00000478-199812000-00001, 9850170.
10. Sauter G, Algaba F, Amin MB, Busch C, Cheville J, Gasser T, Grignon D, Hofstaedter F, Lopez-Beltran A, Epstein JI. Tumours of the urinary system: non-invasive urothelial neoplasias. WHO Classification of Classification of Tumours of the Urinary System and Male Genital Organs 2004, 29-34. Lyon: IARCC Press, Eble JN, Sauter G, Epstein Jl, Sesterhenn I.
11. Sobin LH, Gospodariwicz M, Wittekind C. TNM Classification of Malignant Tumors. 2009, 262-265. UICC International Union Against Cancer: Wiley-Blackwell., http://www.nicc.org/tnm/
12. Witjes JA, Redorta JP, Jacqmin D, Sofras F, Malmström PU, Riedl C, Jocham D, Conti G, Montorsi F, Arentsen HC, Zaak D, Mostafid AH, Babjuk M. Hexaminolevulinate-guided fluorescence cystoscopy in the diagnosis and follow-up of patients with non-muscle-invasive bladder cancer: review of the evidence and recommendations. Eur Urol 2010, 57:607-14. 10.1016/j.eururo.2010.01.025, 20116164.
13. Mowatt G, N'Dow J, Vale L, Nabi G, Boachie C, Cook JA, Fraser C, Griffiths TR, Aberdeen Technology Assessment Review (TAR) Group Photodynamic diagnosis of bladder cancer compared with white light cystoscopy: Systematic review and meta-analysis. Int J Technol Assess Health Care 2011, 27:3-10. 10.1017/S0266462310001364, 21262078, Aberdeen Technology Assessment Review (TAR) Group.
14. Herr HW, Donat SM. A comparison of white-light cystoscopy and narrow-band imaging cystoscopy to detect bladder tumour recurrences. BJU Int 2008, 102:1111-4. 10.1111/j.1464-410X.2008.07846.x, 18778359.
15. Naselli A, Introini C, Timossi L, Spina B, Fontana V, Pezzi R, Germinale F, Bertolotto F, Puppo P. A Randomized prospective trial to assess the impact of transurethral resection in narrow band imaging modality on non-muscle-invasive bladder cancer recurrence. Eur Urol 2012, 61:908-913. 10.1016/j.eururo.2012.01.018, 22280855.
16. Lotan Y, Roehrborn CG. Sensitivity and specificity of commonly available bladder tumour markers versus cytology: results of a comprehensive literature review and meta-analyses. Urology 2003, 61:109-18. 10.1016/S0090-4295(02)02136-2, 12559279.
17. Junker K, Boerner D, Schulze W, Utting M, Schubert J, Werner W. Analysis of genetic alterations in normal bladder urothelium. Urology 2003, 62:1134-8. 10.1016/S0090-4295(03)00692-7, 14665377.
18. Friedrich MG, Hellstern A, Toma MI, Hammerer P, Huland H. Are false-positive urine markers for the detection of bladder carcinoma really wrong or do they predict tumour recurrence?. Eur Urol 2003, 43:146-51. 10.1016/S0302-2838(02)00555-9, 12565772.
19. Halling KC. Vysis UroVysion for the detection of urothelial carcinoma. Expert Rev Mol Diagn 2003, 3:507-19. 10.1586/14737159.3.4.507, 12877389.
20. Halling KC, King W, Sokolova IA, Karnes RJ, Meyer RG, Powell EL, Sebo TJ, Cheville JC, Clayton AC, Krajnik KL, Ebert TA, Nelson RE, Burkhardt HM, Ramakumar S, Stewart CS, Pankratz VS, Lieber MM, Blute ML, Zincke H, Seelig SA, Jenkins RB, O'Kane DJ. A comparison of BTA stat, hemoglobin dipstick, telomerase and Vysis UroVysion assays for the detection of urothelial carcinoma in urine. J Urol 2002, 167:2001-6. 10.1016/S0022-5347(05)65072-0, 11956427.
21. Kamat AM, Dickstein RJ, Messetti F, Anderson R, Pretzsch SM, Gonzalez GN, Katz RL, Khanna A, Zaidi T, Wu X, Grossman HB, Dinney CP. Use of fluorescence in situ hybridization to predict response to bacillus calmette-Guérin therapy for bladder cancer: results of a prospective trial. J Urol 2012, 187:862-867. 10.1016/j.juro.2011.10.144, 22245325.
22. Terrell JD, Elias KJ, Sagalowsky AI, Lotain Y. Patients with a negative cystoscopy and negative Nmp22® Bladdercheck® test are at low risk of missed transitional cell carcinoma of the bladder: a prospective evaluation. International Braz J Urol 2011, 37:706-711. 10.1590/S1677-55382011000600004, 22234001.
23. Shariat SF, Savage C, Chromecki TF, Sun M, Scherr DS, Lee RK, Lughezzani G, Remzi M, Marberger MJ, Karakiewicz PI, Vickers AJ. Assessing the clinical benefit of nuclear matrix protein 22 in the surveillance of patients with nonmuscle-invasive bladder cancer and negative cytology a decision-curve analysis. Cancer 2011, 117:2892-7. 10.1002/cncr.25903, 3334293, 21692050.
24. Pawinski A, Sylvester R, Kurth KH, Bouffioux C, van der Meijden A, Parmar MK, Bijnens L. A combined analysis of European Organisation for Cancer Research and Treatment of Cancer and Medical Research Cancer clinical trials for the prophylactic treatment of stage Ta-T1 bladder cancer. J Urol 1996, 156:1934-41. 10.1016/S0022-5347(01)65396-5, 8911360.
25. Lerner SP, Au JL. Risk-adapted use of intravesical chemotherapy. BJU Int 2008, 102:1247-53. 10.1111/j.1464-410X.2008.07967.x, 19035889.
26. Sylvester RJ, Oosterlinck W, van der Meijden AP. A single immediate postoperative instillation of chemotherapy decreases the risk of recurrence in patients with stage Ta T1 bladder cancer: a meta-analysis of published results of randomized clinical trials. J Urol 2004, 171:2186-90. 10.1097/01.ju.0000125486.92260.b2, 15126782.
27. Madeb R, Golijanin D, Noyes K, Fisher S, Stephenson JJ, Long SR, Knopf J, Lyman GH, Messing EM. Treatment of nonmuscle invading bladder cancer: do physicians in the United States practice evidence based medicine? The use and economic implications of intravesical chemotherapy after transurethral resection of bladder tumors. Cancer 2009, 115:2660-2670. 10.1002/cncr.24311, 2769205, 19455607.
28. Sylvester RJ, van der Meijden AP, Lamm DL. Intravesical bacillus Calmette-Guerin reduces the risk of progression in patients with superficial bladder cancer: a meta-analysis of the published results of randomized clinical trials. J Urol 2002, 168:1964-70. 10.1016/S0022-5347(05)64273-5, 12394686.
29. Di Stasi SM, Giannantoni A, Giurioli A, Valenti M, Zampa G, Storti L, Attisani F, De Carolis A, Capelli G, Vespasiani G, Stephen RL. Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial. Lancet Oncol 2006, 7:43-51. 10.1016/S1470-2045(05)70472-1, 16389183.
30. Di Stasi SM, Valenti M, Verri C, Liberati E, Giurioli A, Leprini G, Masedu F, Ricci AR, Micali F, Vespasiani G. Electromotive instillation of mitomycin immediately before transurethral resection for patients with primary urothelial non-muscle invasive bladder cancer: a randomised controlled trial. Lancet Oncol 2011, 12:871-79. 10.1016/S1470-2045(11)70190-5, 21831711.
31. Amery S, Chatterton K, Zisengwe G, Mukwahuri A, Dickenson F, Khan S, Thomas K, O'Brien T. Abstract 50: Initial experience with sequential BCG/electromotive drug administration (EMDA) mitomycin-C (MMC) as the standard intravesical regimen for high-risk non-muscle invasive bladder cancer. British Association of Urological Surgeons Annual Meeting 25-28, Glasgow 2012,
32. Colombo R, Lev A, Da Pozzo LF, Freschi M, Gallus G, Rigatti P. A new approach using local combined microwave hyperthermia and chemotherapy in superficial transitional bladder carcinoma treatment. J Urol 1995, 153:959-63. 10.1016/S0022-5347(01)67613-4, 7853583.
33. Colombo R, Salonia A, Leib Z, Pavone-Macaluso M, Engelstein D. Long-term outcomes of a randomized controlled trial comparing thermochemotherapy with mitomycin-C alone as adjuvant treatment for non-muscle-invasive bladder cancer (NMIBC). BJU Int 2011, 107:912-918. 10.1111/j.1464-410X.2010.09654.x, 21029314.
34. Lammers RJ, Witjes JA, Inman BA, Leibovitch I, Laufer M, Nativ O, Colombo R. The Role of a Combined Regimen With Intravesical Chemotherapy and Hyperthermia in the Management of Non-muscle-invasive Bladder Cancer: A Systematic Review. Eur Urol 2011, 60:81-93. 10.1016/j.eururo.2011.04.023, 21531502.
35. Shelley M, Cleves A, Wilt T, Mason M. Gemcitabine chemotherapy for the treatment of metastatic bladder cancer. BJU Int 2011, 108:168-79. 10.1111/j.1464-410X.2011.10341.x, 21718430.
36. Shelley MD, Jones G, Cleves A, Wilt TJ, Mason MD, Kynaston HG. Intravesical gemcitabine therapy for non-muscle invasive bladder cancer (NMIBC): a systematic review. BJU Int 2012, 109:496-505. 10.1111/j.1464-410X.2011.10880.x, 22313502.
37. Skinner EC, Goldman B, Sakr WA, Petrylak DP, Lenz HJ, Lee CT, Wilson SS, Lerner SP, Tangen CM, Thompson IM. SWOG S0353: Phase II Trial of intravesical gemcitabine in patients with non-muscle invasive bladder cancer who recurred following at least two prior courses of BCG. American Urological Association Annual Meeting: 19-23 May 2012; Atlanta
38. Advanced Bladder Cancer Meta-analysis Collaboration Neoadjuvant chemotherapy in invasive bladder cancer: a systematic review and meta-analysis. Lancet 2003, 361:1927-34. 10.1016/S0140-6736(03)13580-5, 12801735, Advanced Bladder Cancer Meta-analysis Collaboration.
39. Grossman HB, Natale RB, Tangen CM, Speights VO, Vogelzang NJ, Trump DL, deVere White RW, Sarosdy MF, Wood DP, Raghavan D, Crawford ED. Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer. N Engl J Med 2003, 349:859-66. 10.1056/NEJMoa022148, 12944571.
40. Novotny V, Hakenberg OW, Wiessner D, Heberling U, Litz RJ, Oehlschlaeger S, Wirth MP. Perioperative complications of radical cystectomy in a contemporary series. Eur Urol 2007, 51:397-401. 10.1016/j.eururo.2006.06.014, 16905242.
41. Haber GP, Crouzet S, Gill IS. Laparoscopic and robotic assisted radical cystectomy for bladder cancer: a critical analysis. Eur Urol 2008, 54:54-62. 10.1016/j.eururo.2008.03.076, 18403100.
42. Haber GP, Gill IS. Laparoscopic radical cystectomy for cancer: oncological outcomes at up to 5 years. BJU Int 2007, 100:137-42. 10.1111/j.1464-410X.2007.06865.x, 17552961.
43. Ng CK, Kauffman EC, Lee MM, Otto BJ, Portnoff A, Ehrlich JR, Schwartz MJ, Wang GJ, Scherr DS. A comparison of postoperative complications in open versus robotic cystectomy. Eur Urol 2010, 57:274-81. 10.1016/j.eururo.2009.06.001, 19560255.
44. Hayn MH, Hellenthal NJ, Seixas-Mikelus SA, Mansour AM, Stegemann A, Hussain A, Guru KA. Is patient outcome compromised during the initial experience with robot-assisted radical cystectomy? Results of 164 consecutive cases. BJU Int 2011, 108:882-7.
45. Pruthi RS, Nielsen ME, Nix J, Smith A, Schultz H, Wallen EM. Robotic radical cystectomy for bladder cancer: surgical and pathological outcomes in 100 consecutive cases. J Urol 2010, 183:510-4. 10.1016/j.juro.2009.10.027, 20006884.
46. Kauffman EC, Ng CK, Lee MM, Otto BJ, Wang GJ, Scherr DS. Early oncological outcomes for bladder urothelial carcinoma patients treated with robotic-assisted radical cystectomy. BJU Int 2011, 107:628-35. 10.1111/j.1464-410X.2010.09577.x, 20883479.
47. Dasgupta P, Rimington P, Murphy D, Challacombe B, Hemal A, Elhage O, Khan MS. Robotic assisted radical cystectomy: short to medium-term oncologic and functional outcomes. Int J Clin Pract 2008, 62:1709-14. 10.1111/j.1742-1241.2008.01858.x, 19143856.
48. Hellenthal NJ, Hussain A, Andrews PE, Carpentier P, Castle E, Dasgupta P, Kaouk J, Khan S, Kibel A, Kim H, Manoharan M, Menon M, Mottrie A, Ornstein D, Palou J, Peabody J, Pruthi R, Richstone L, Schanne F, Stricker H, Thomas R, Wiklund P, Wilding G, Guru KA. Lymphadenectomy at the time of robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. BJU Int 2011, 107:642-646. 10.1111/j.1464-410X.2010.09473.x, 20575975.
49. Hellenthal NJ, Hussain A, Andrews PE, Carpentier P, Castle E, Dasgupta P, Kaouk J, Khan S, Kibel A, Kim H, Manoharan M, Menon M, Mottrie A, Ornstein D, Palou J, Peabody J, Pruthi R, Richstone L, Schanne F, Stricker H, Thomas R, Wiklund P, Wilding G, Guru KA. Surgical margin status after robot assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. J Urol 2010, 184:87-91. 10.1016/j.juro.2010.03.037, 20478596.
50. Ahmed K, Hayn MH, Stegemann AP, Agarwal PK, Badani KK, Balbay MD, Castle EP, Dasgupta P, Ghavamian R, Guru KA, Hemal AK, Hollenbeck BK, Josephson D, Kader AK, Kibel AS, Menon M, Mottrie A, Nepple K, Pattaras JG, Peabody JO, Poulakis V, Pruthi RS, Redorta JP, Rha KH, Richstone L, Saar M, Scherr DS, Siemer S, Stoeckle M, Wallen EM, et al. Comparison of outcomes between intra-corporeal and extra-corporeal urinary diversion after robot-assisted radical cystectomy - the IRCC results. American Urological Association Annual Meeting: 19-23 May 2012; Atlanta
51. Pruthi RS, Nix J, McRackan D, Hickerson A, Nielsen ME, Raynor M, Wallen EM. Robotic-assisted laparoscopic intracorporeal urinary diversion. Eur Urol 2010, 57:1013-21. 10.1016/j.eururo.2009.12.028, 20079567.
52. Guru K, Seixas-Mikelus SA, Hussain A, Blumenfeld AJ, Nyquist J, Chandrasekhar R, Wilding GE. Robot-assisted intracorporeal ileal conduit: marionette technique and initial experience at Roswell Park Cancer Institute. Urology 2010, 76:866-71. 10.1016/j.urology.2009.12.082, 20451963.
53. Jonsson MN, Adding LC, Hosseini A, Schumacher MC, Volz D, Nilsson A, Carlsson S, Wiklund NP. Robot-assisted radical cystectomy with intracorporeal urinary diversion in patients with transitional cell carcinoma of the bladder. Eur Urol 2011, 60:1066-73. 10.1016/j.eururo.2011.07.035, 21852033.
54. Jonsson MN, Adding LC, Hosseini A, Schumacher MC, Volz D, Nilsson A, Carlsson S, Wiklund NP. Robot-assisted radical cystectomy with intracorporeal urinary diversion in patients with transitional cell carcinoma of the bladder. Eur Urol 2011, 60:1066-73. 10.1016/j.eururo.2011.07.035, 21852033.
55. Open vs robotic-assisted radical cystectomy: a randomized trial. , http://clinicaltrials.gov NCT01157676
56. Bladder cancer: open versus laparoscopic or robotic cystectomy. , http://www.controlled-trials.com ISRCTN38528926
57. Efstathiou JA, Spiegel DY, Shipley WU, Heney NM, Kaufman DS, Niemierko A, Coen JJ, Skowronski RY, Paly JJ, McGovern FJ, Zietman AL. Long-term outcomes of selective bladder preservation by combined-modality therapy for invasive bladder cancer: the MGH experience. Eur Urol 2012, 61:705-711. 10.1016/j.eururo.2011.11.010, 22101114.