Recognition of the HIV capsid by the TRIM5α restriction factor is mediated by a subset of pre-existing conformations of the TRIM5α SPRY domain

Biochemistry

Volumn 53, Issue 9, 2014, Pages 1466-1476

  Kovalskyy, Dmytro B ^a   Ivanov, Dmitri N ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC LEVELS; BINDING MODES; HIGH-RESOLUTION MODELS; HOST-PATHOGEN INTERACTIONS; INTRINSIC DISORDER; KEY DETERMINANTS; REPLICA EXCHANGE MOLECULAR DYNAMICS; SYMMETRY AXIS;

ONCOGENIC VIRUSES;

BINDING ENERGY;

TRIPARTITE MOTIF PROTEIN 5;

ARTICLE; BINDING KINETICS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; SPRY DOMAIN; VIRUS CAPSID; VIRUS MUTANT;

CAPSID; CAPSID PROTEINS; CARRIER PROTEINS; HIV-1; HUMANS; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY;

EID: 84896091636     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi4014962     Document Type: Article

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