Jolkinolide B inhibits RANKL-induced osteoclastogenesis by suppressing the activation NF-κB and MAPK signaling pathways

Biochemical and Biophysical Research Communications

Volumn 445, Issue 2, 2014, Pages 282-288

  Ma, Xiaojun ^a   Liu, Yupeng ^a   Zhang, Yao ^a   Yu, Xiaobing ^a   Wang, Weiming ^a   Zhao, Dewei ^a  

^a DALIAN UNIVERSITY   (China)

Author keywords

Bone resorption; Jolkinolide B; MAPKs; NF B; Osteoclast

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CALCITONIN RECEPTOR; CATHEPSIN K; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JOLKINOLIDE B; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; OSTEOCLAST DIFFERENTIATION FACTOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; EUPHORBIA; EUPHORBIA FISCHERIANA; GIANT CELL; MACROPHAGE; MARKER GENE; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EUPHORBIA FISCHERIANA;

BONE RESORPTION; JOLKINOLIDE B; MAPKS; NF-ΚB; OSTEOCLAST;

ANIMALS; BONE RESORPTION; CELL DIFFERENTIATION; CELLS, CULTURED; DITERPENES; DRUGS, CHINESE HERBAL; EUPHORBIA; MICE; MICE, INBRED C57BL; NF-KAPPA B; OSTEOCLASTS; RANK LIGAND; SIGNAL TRANSDUCTION;

EID: 84896086571     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.01.145     Document Type: Article

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