-
1
-
-
33746570647
-
Tracking STAT nuclear traffic
-
DOI 10.1038/nri1885, PII NRI1885
-
Reich N. C., Liu L., Tracking STAT nuclear traffic. Nature Reviews Immunology 2006 6 8 602 612 2-s2.0-33746570647 10.1038/nri1885 (Pubitemid 44134093)
-
(2006)
Nature Reviews Immunology
, vol.6
, Issue.8
, pp. 602-612
-
-
Reich, N.C.1
Liu, L.2
-
2
-
-
84865692047
-
Targeted therapies: STAT3 and EGFR target resistance
-
10.1038/nrclinonc.2012.140
-
Kirk R., Targeted therapies: STAT3 and EGFR target resistance. Nature Reviews Clinical Oncology 2012 9 489 10.1038/nrclinonc.2012.140
-
(2012)
Nature Reviews Clinical Oncology
, vol.9
, pp. 489
-
-
Kirk, R.1
-
3
-
-
34249660614
-
SOCS proteins, cytokine signalling and immune regulation
-
DOI 10.1038/nri2093, PII NRI2093
-
Yoshimura A., Naka T., Kubo M., SOCS proteins, cytokine signalling and immune regulation. Nature Reviews Immunology 2007 7 6 454 465 2-s2.0-34249660614 10.1038/nri2093 (Pubitemid 46834848)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.6
, pp. 454-465
-
-
Yoshimura, A.1
Naka, T.2
Kubo, M.3
-
4
-
-
70949094349
-
The JAK2 inhibitor AZD1480 potently blocks stat3 signaling and oncogenesis in solid tumors
-
2-s2.0-70949094349 10.1016/j.ccr.2009.10.015
-
Hedvat M., Huszar D., Herrmann A., Gozgit J. M., Schroeder A., Sheehy A., Buettner R., Proia D., Kowolik C. M., Xin H., Armstrong B., Bebernitz G., Weng S., Wang L., Ye M., McEachern K., Chen H., Morosini D., Bell K., Alimzhanov M., Ioannidis S., McCoon P., Cao Z. A., Yu H., Jove R., Zinda M., The JAK2 inhibitor AZD1480 potently blocks stat3 signaling and oncogenesis in solid tumors. Cancer Cell 2009 16 6 487 497 2-s2.0-70949094349 10.1016/j.ccr.2009.10.015
-
(2009)
Cancer Cell
, vol.16
, Issue.6
, pp. 487-497
-
-
Hedvat, M.1
Huszar, D.2
Herrmann, A.3
Gozgit, J.M.4
Schroeder, A.5
Sheehy, A.6
Buettner, R.7
Proia, D.8
Kowolik, C.M.9
Xin, H.10
Armstrong, B.11
Bebernitz, G.12
Weng, S.13
Wang, L.14
Ye, M.15
McEachern, K.16
Chen, H.17
Morosini, D.18
Bell, K.19
Alimzhanov, M.20
Ioannidis, S.21
McCoon, P.22
Cao, Z.A.23
Yu, H.24
Jove, R.25
Zinda, M.26
more..
-
5
-
-
58649119388
-
Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment
-
2-s2.0-58649119388 10.1016/j.ccr.2008.12.018
-
Kortylewski M., Xin H., Kujawski M., Lee H., Liu Y., Harris T., Drake C., Pardoll D., Yu H., Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment. Cancer Cell 2009 15 2 114 123 2-s2.0-58649119388 10.1016/j.ccr.2008.12.018
-
(2009)
Cancer Cell
, vol.15
, Issue.2
, pp. 114-123
-
-
Kortylewski, M.1
Xin, H.2
Kujawski, M.3
Lee, H.4
Liu, Y.5
Harris, T.6
Drake, C.7
Pardoll, D.8
Yu, H.9
-
6
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
2-s2.0-70350500225 10.1038/nrc2734
-
Yu H., Pardoll D., Jove R., STATs in cancer inflammation and immunity: a leading role for STAT3. Nature Reviews Cancer 2009 9 11 798 809 2-s2.0-70350500225 10.1038/nrc2734
-
(2009)
Nature Reviews Cancer
, vol.9
, Issue.11
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
7
-
-
63249092765
-
Persistently activated Stat3 maintains constitutive NF- B activity in tumors
-
2-s2.0-63249092765 10.1016/j.ccr.2009.02.015
-
Lee H., Herrmann A., Deng J.-H., Kujawski M., Niu G., Li Z., Forman S., Jove R., Pardoll D. M., Yu H., Persistently activated Stat3 maintains constitutive NF- B activity in tumors. Cancer Cell 2009 15 4 283 293 2-s2.0-63249092765 10.1016/j.ccr.2009.02.015
-
(2009)
Cancer Cell
, vol.15
, Issue.4
, pp. 283-293
-
-
Lee, H.1
Herrmann, A.2
Deng, J.-H.3
Kujawski, M.4
Niu, G.5
Li, Z.6
Forman, S.7
Jove, R.8
Pardoll, D.M.9
Yu, H.10
-
8
-
-
84865295971
-
STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma
-
Tu B., Du L., Fan Q. M., Tang Z., Tang T. T., STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma. Cancer Letters 2012 325 80 88
-
(2012)
Cancer Letters
, vol.325
, pp. 80-88
-
-
Tu, B.1
Du, L.2
Fan, Q.M.3
Tang, Z.4
Tang, T.T.5
-
9
-
-
78649982367
-
STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors
-
2-s2.0-78649982367 10.1038/nm.2250
-
Lee H., Deng J., Kujawski M., Yang C., Liu Y., Herrmann A., Kortylewski M., Horne D., Somlo G., Forman S., Jove R., Yu H., STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors. Nature Medicine 2010 16 12 1421 1428 2-s2.0-78649982367 10.1038/nm.2250
-
(2010)
Nature Medicine
, vol.16
, Issue.12
, pp. 1421-1428
-
-
Lee, H.1
Deng, J.2
Kujawski, M.3
Yang, C.4
Liu, Y.5
Herrmann, A.6
Kortylewski, M.7
Horne, D.8
Somlo, G.9
Forman, S.10
Jove, R.11
Yu, H.12
-
10
-
-
84861399789
-
S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites
-
Deng J., Liu Y., Lee H., S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites. Cancer Cell 2012 21 642 654
-
(2012)
Cancer Cell
, vol.21
, pp. 642-654
-
-
Deng, J.1
Liu, Y.2
Lee, H.3
-
11
-
-
80051926611
-
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
-
2-s2.0-80051926611 10.1038/nature10337
-
de Lau W., Barker N., Low T. Y., Koo B.-K., Li V. S. W., Teunissen H., Kujala P., Haegebarth A., Peters P. J., van de Wetering M., Stange D. E., van Es J., Guardavaccaro D., Schasfoort R. B. M., Mohri Y., Nishimori K., Mohammed S., Heck A. J. R., Clevers H., Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 2011 476 7360 293 297 2-s2.0-80051926611 10.1038/nature10337
-
(2011)
Nature
, vol.476
, Issue.7360
, pp. 293-297
-
-
De Lau, W.1
Barker, N.2
Low, T.Y.3
Koo, B.-K.4
Li, V.S.W.5
Teunissen, H.6
Kujala, P.7
Haegebarth, A.8
Peters, P.J.9
Van De Wetering, M.10
Stange, D.E.11
Van Es, J.12
Guardavaccaro, D.13
Schasfoort, R.B.M.14
Mohri, Y.15
Nishimori, K.16
Mohammed, S.17
Heck, A.J.R.18
Clevers, H.19
-
12
-
-
80053560465
-
LGR4 and LGR5 are R-spondin receptors mediating Wnt/ β -catenin and Wnt/PCP signalling
-
2-s2.0-80053560465 10.1038/embor.2011.175
-
Glinka A., Dolde C., Kirsch N., Huang Y.-L., Kazanskaya O., Ingelfinger D., Boutros M., Cruciat C.-M., Niehrs C., LGR4 and LGR5 are R-spondin receptors mediating Wnt/ β -catenin and Wnt/PCP signalling. EMBO Reports 2011 12 10 1055 1061 2-s2.0-80053560465 10.1038/embor.2011.175
-
(2011)
EMBO Reports
, vol.12
, Issue.10
, pp. 1055-1061
-
-
Glinka, A.1
Dolde, C.2
Kirsch, N.3
Huang, Y.-L.4
Kazanskaya, O.5
Ingelfinger, D.6
Boutros, M.7
Cruciat, C.-M.8
Niehrs, C.9
-
13
-
-
84870252814
-
The complex world of WNT receptor signalling
-
Niehrs C., The complex world of WNT receptor signalling. Nature Reviews Molecular Cell Biology 2012 13 767 779
-
(2012)
Nature Reviews Molecular Cell Biology
, vol.13
, pp. 767-779
-
-
Niehrs, C.1
-
14
-
-
84875420089
-
Lgr4-mediated Wnt/ β -catenin signaling in peritubular myoid cells is essential for spermatogenesis
-
Qian Y., Liu S., Guan Y., Lgr4-mediated Wnt/ β -catenin signaling in peritubular myoid cells is essential for spermatogenesis. Development 2013 140 1751 1761
-
(2013)
Development
, vol.140
, pp. 1751-1761
-
-
Qian, Y.1
Liu, S.2
Guan, Y.3
-
15
-
-
69049090918
-
Regulation of bone formation and remodeling by G-protein-coupled receptor 48
-
2-s2.0-69049090918 10.1242/dev.033571
-
Luo J., Zhou W., Zhou X., Li D., Weng J., Yi Z., Cho S. G., Li C., Yi T., Wu X., Li X.-Y., de Crombrugghe B., Höök M., Liu M., Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development 2009 136 16 2747 2756 2-s2.0-69049090918 10.1242/dev.033571
-
(2009)
Development
, vol.136
, Issue.16
, pp. 2747-2756
-
-
Luo, J.1
Zhou, W.2
Zhou, X.3
Li, D.4
Weng, J.5
Yi, Z.6
Cho, S.G.7
Li, C.8
Yi, T.9
Wu, X.10
Li, X.-Y.11
De Crombrugghe, B.12
Höök, M.13
Liu, M.14
-
16
-
-
49449109436
-
Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4
-
2-s2.0-49449109436 10.1002/dvdy.21639
-
Mohri Y., Kato S., Umezawa A., Okuyama R., Nishimori K., Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4. Developmental Dynamics 2008 237 8 2235 2242 2-s2.0-49449109436 10.1002/dvdy.21639
-
(2008)
Developmental Dynamics
, vol.237
, Issue.8
, pp. 2235-2242
-
-
Mohri, Y.1
Kato, S.2
Umezawa, A.3
Okuyama, R.4
Nishimori, K.5
-
17
-
-
43149099246
-
Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2
-
DOI 10.1073/pnas.0708257105
-
Weng J., Luo J., Cheng X., Jin C., Zhou X., Qu J., Tu L., Ai D., Li D., Wang J., Martin J. F., Amendt B. A., Liu M., Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2. Proceedings of the National Academy of Sciences of the United States of America 2008 105 16 6081 6086 2-s2.0-43149099246 10.1073/pnas.0708257105 (Pubitemid 351758402)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.16
, pp. 6081-6086
-
-
Weng, J.1
Luo, J.2
Cheng, X.3
Jin, C.4
Zhou, X.5
Qu, J.6
Tu, L.7
Ai, D.8
Li, D.9
Wang, J.10
Martin, J.F.11
Amendt, B.A.12
Liu, M.13
-
18
-
-
79960945902
-
Conditional knockout of Lgr4 leads to impaired ductal elongation and branching morphogenesis in mouse mammary glands
-
2-s2.0-79960945902 10.1159/000329476
-
Oyama K., Mohri Y., Sone M., Nawa A., Nishimori K., Conditional knockout of Lgr4 leads to impaired ductal elongation and branching morphogenesis in mouse mammary glands. Sexual Development 2011 5 4 205 212 2-s2.0-79960945902 10.1159/000329476
-
(2011)
Sexual Development
, vol.5
, Issue.4
, pp. 205-212
-
-
Oyama, K.1
Mohri, Y.2
Sone, M.3
Nawa, A.4
Nishimori, K.5
-
19
-
-
73649092120
-
G protein-coupled receptor 48 upregulates estrogen receptor α expression via cAMP/PKA signaling in the male reproductive tract
-
2-s2.0-73649092120 10.1242/dev.040659
-
Li X.-Y., Lu Y., Sun H.-Y., Wang J.-Q., Yang J., Zhang H.-J., Fan N.-G., Xu J., Jiang J.-J., Liu R.-Y., Li D.-L., Liu M.-Y., Ning G., G protein-coupled receptor 48 upregulates estrogen receptor α expression via cAMP/PKA signaling in the male reproductive tract. Development 2010 137 1 151 157 2-s2.0-73649092120 10.1242/dev.040659
-
(2010)
Development
, vol.137
, Issue.1
, pp. 151-157
-
-
Li, X.-Y.1
Lu, Y.2
Sun, H.-Y.3
Wang, J.-Q.4
Yang, J.5
Zhang, H.-J.6
Fan, N.-G.7
Xu, J.8
Jiang, J.-J.9
Liu, R.-Y.10
Li, D.-L.11
Liu, M.-Y.12
Ning, G.13
-
20
-
-
84879345191
-
Lgr4 in ocular evelopment and glaucoma
-
987494 10.1155/2013/987494
-
Siwko S., Lai L., Weng J., Liu M., Lgr4 in ocular evelopment and glaucoma. Journal of Ophthalmology 2013 2013 9 987494 10.1155/2013/987494
-
(2013)
Journal of Ophthalmology
, vol.2013
, pp. 9
-
-
Siwko, S.1
Lai, L.2
Weng, J.3
Liu, M.4
-
21
-
-
84878143904
-
Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits
-
Styrkarsdottir U., Thorleifsson G., Sulem P., Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits. Nature 2013 497 517 520
-
(2013)
Nature
, vol.497
, pp. 517-520
-
-
Styrkarsdottir, U.1
Thorleifsson, G.2
Sulem, P.3
-
22
-
-
33846209564
-
Kip1 enhances carcinoma cell invasiveness and metastasis
-
DOI 10.1158/0008-5472.CAN-06-2629
-
Gao Y., Kitagawa K., Hiramatsu Y., Kikuchi H., Isobe T., Shimada M., Uchida C., Hattori T., Oda T., Nakayama K., Nakayama K. I., Tanaka T., Konno H., Kitagawa M., Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis. Cancer Research 2006 66 24 11623 11631 2-s2.0-33846209564 10.1158/0008-5472.CAN-06-2629 (Pubitemid 46094173)
-
(2006)
Cancer Research
, vol.66
, Issue.24
, pp. 11623-11631
-
-
Gao, Y.1
Kitagawa, K.2
Hiramatsu, Y.3
Kikuchi, H.4
Isobe, T.5
Shimada, M.6
Uchida, C.7
Hattori, T.8
Oda, T.9
Nakayama, K.10
Nakayama, K.I.11
Tanaka, T.12
Konno, H.13
Kitagawa, M.14
-
23
-
-
84889045084
-
GPR48, a poor prognostic factor, promotes tumor metastasis and activates β -catenin/TCF signaling in colorectal cancer
-
10.1093/carcin/bgt229
-
Wu J., Xie N., Xie K., GPR48, a poor prognostic factor, promotes tumor metastasis and activates β -catenin/TCF signaling in colorectal cancer. Carcinogenesis 2013 34 12 2861 2869 10.1093/carcin/bgt229
-
(2013)
Carcinogenesis
, vol.34
, Issue.12
, pp. 2861-2869
-
-
Wu, J.1
Xie, N.2
Xie, K.3
-
24
-
-
84878233672
-
Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression
-
10.1074/jbc.M113.455535
-
Du B., Luo W., Li R., Lgr4/Gpr48 negatively regulates TLR2/4-associated pattern recognition and innate immunity by targeting CD14 expression. The Journal of Biological Chemistry 2013 288 15131 15141 10.1074/jbc.M113.455535
-
(2013)
The Journal of Biological Chemistry
, vol.288
, pp. 15131-15141
-
-
Du, B.1
Luo, W.2
Li, R.3
|