Washing older blood units before transfusion reduces plasma iron and improves outcomes in experimental canine pneumonia

Blood

Volumn 123, Issue 9, 2014, Pages 1403-1411

  Corteś Puch, Irene ^a   Wang, Dong ^a   Sun, Junfeng ^a   Solomon, Steven B ^a   Remy, Kenneth E ^a   Fernandez, Melinda ^a   Feng, Jing ^a   Kanias, Tamir ^b   Bellavia, Landon ^c   Sinchar, Derek ^b   Perlegas, Andreas ^c   Solomon, Michael A ^a,d   Kelley, Walter E ^e   Popovsky, Mark A ^f   Gladwin, Mark T ^b,g   Kim Shapiro, Daniel B ^c   Klein, Harvey G ^h   Natanson, Charles ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c WAKE FOREST UNIVERSITY   (United States)

^d NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^e Oklahoma Blood Institute   (United States)

^f HAEMONETICS CORPORATION   (United States)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^h NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL FREE HEMOGLOBIN; HAPTOGLOBIN; HEMOGLOBIN; UNCLASSIFIED DRUG; IRON;

ANIMAL EXPERIMENT; ARTICLE; BEAGLE; CONTROLLED STUDY; ERYTHROCYTE TRANSFUSION; EXCHANGE BLOOD TRANSFUSION; HEART FUNCTION; HEMATOLOGICAL PROCEDURE; HEMOGLOBIN BLOOD LEVEL; IN VITRO STUDY; IRON BLOOD LEVEL; LIVER FUNCTION; LUNG INJURY; NONHUMAN; ORGAN INJURY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SHOCK; STAPHYLOCOCCAL PNEUMONIA; SURVIVAL RATE; WASHING OLDER RED BLOOD CELL; ACUTE LUNG INJURY; ANIMAL; BLOOD; BLOOD SAMPLING; BLOOD STORAGE; CHEMISTRY; CONTROLLED CLINICAL TRIAL; CYTOLOGY; DISEASE MODEL; DOG; DOWN REGULATION; ERYTHROCYTE; ISOLATION AND PURIFICATION; METHODOLOGY; MORTALITY; PLASMA; TREATMENT OUTCOME;

ACUTE LUNG INJURY; ANIMALS; BLOOD PRESERVATION; BLOOD SPECIMEN COLLECTION; DISEASE MODELS, ANIMAL; DOGS; DOWN-REGULATION; ERYTHROCYTE TRANSFUSION; ERYTHROCYTES; IRON; PLASMA; PNEUMONIA, STAPHYLOCOCCAL; TREATMENT OUTCOME;

EID: 84896057236     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-11-539353     Document Type: Article

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