A canine model of septic shock: Balancing animal welfare and scientific relevance

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 293, Issue 4, 2007, Pages

  Minneci, Peter C ^a,d   Deans, Katherine J ^a,d   Hansen, Bernie ^b   Parent, Chantal ^a   Romines, Chris ^a   Gonzales, Denise A ^a   Ying, Sai Xia ^c   Munson, Peter ^c   Suffredini, Anthony F ^a   Feng, Jing ^a   Solomon, Michael A ^a   Banks, Steven M ^a   Kern, Steven J ^a   Danner, Robert L ^a   Eichacker, Peter Q ^a   Natanson, Charles ^a   Solomon, Steven B ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Dog; Sepsis; Staphylococcus aureus

Indexed keywords

ANALGESIC AGENT; ANTIBIOTIC AGENT; CYTOKINE; FENTANYL; HYPERTENSIVE FACTOR; INTERLEUKIN 1; LACTIC ACID; LIVER ENZYME; MEDETOMIDINE; MIDAZOLAM; SEDATIVE AGENT; SODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL WELFARE; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; DISEASE SEVERITY; DOG; LEUKOCYTE COUNT; LUNG ARTERY PRESSURE; LUNG HEMODYNAMICS; LUNG INJURY; METABOLISM; NONHUMAN; PH; PNEUMONIA; PRIORITY JOURNAL; SEDATION; SEPTIC SHOCK; SODIUM BLOOD LEVEL; STAPHYLOCOCCUS AUREUS; SURVIVAL RATE; THROMBOCYTE COUNT; URINE VOLUME; VALIDATION PROCESS;

ANALGESICS; ANIMAL WELFARE; ANIMALS; ANTI-BACTERIAL AGENTS; BIOMEDICAL RESEARCH; BLOOD CHEMICAL ANALYSIS; BLOOD PROTEINS; CYTOKINES; DISEASE MODELS, ANIMAL; DOGS; FLUID THERAPY; HEMATOLOGIC TESTS; HYPNOTICS AND SEDATIVES; KIDNEY DISEASES; KIDNEY FUNCTION TESTS; LIVER DISEASES; LIVER FUNCTION TESTS; PNEUMONIA, STAPHYLOCOCCAL; REPRODUCIBILITY OF RESULTS; RESPIRATION, ARTIFICIAL; SEVERITY OF ILLNESS INDEX; SHOCK, SEPTIC; STAPHYLOCOCCUS AUREUS; TIME FACTORS; VASOCONSTRICTOR AGENTS;

EID: 35348973516     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00589.2007     Document Type: Article

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