Anthocyanins Protect against Kainic Acid-induced Excitotoxicity and Apoptosis via ROS-activated AMPK Pathway in Hippocampal Neurons

CNS Neuroscience and Therapeutics

Volumn 20, Issue 4, 2014, Pages 327-338

  Ullah, Ikram ^a   Park, Hyun Young ^b   Kim, Myeong Ok ^a  

^a Gyeongsang National University   (South Korea)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Anthocyanins; Excitotoxicity; Kainic acid; Neurodegeneration; Neuroprotection

Indexed keywords

ADENYLATE KINASE; ANTHOCYANIN; CALCIUM; CASPASE 3; COMPOUND C; CYTOCHROME C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; KAINIC ACID; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR STIMULATING AGENT; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; EXCITOTOXICITY; FEMALE; HIPPOCAMPAL NEURONAL CULTURE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; HIPPOCAMPUS; METABOLISM; MITOCHONDRION; NERVE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TOXICITY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTHOCYANINS; APOPTOSIS; CALCIUM; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; KAINIC ACID; MICE; MITOCHONDRIA; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 84896054199     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12218     Document Type: Article

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