-
1
-
-
77951107086
-
Synthetic biology: applications come of age
-
Khalil A.S., Collins J.J. Synthetic biology: applications come of age. Nat Rev Genet 2010, 11:367-379.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 367-379
-
-
Khalil, A.S.1
Collins, J.J.2
-
2
-
-
84867218981
-
Innovation at the intersection of synthetic and systems biology
-
Lanza A.M., Crook N.C., Alper H.S. Innovation at the intersection of synthetic and systems biology. Curr Opin Biotechnol 2012, 23:712-717.
-
(2012)
Curr Opin Biotechnol
, vol.23
, pp. 712-717
-
-
Lanza, A.M.1
Crook, N.C.2
Alper, H.S.3
-
3
-
-
84880938470
-
TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins
-
Doyle E.L., Stoddard B.L., Voytas D.F., Bogdanove A.J. TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins. Trends Cell Biol 2013.
-
(2013)
Trends Cell Biol
-
-
Doyle, E.L.1
Stoddard, B.L.2
Voytas, D.F.3
Bogdanove, A.J.4
-
4
-
-
84884856342
-
Cas9 as a versatile tool for engineering biology
-
Mali P., Esvelt K.M., Church G.M. Cas9 as a versatile tool for engineering biology. Nat Methods 2013, 10:957-963.
-
(2013)
Nat Methods
, vol.10
, pp. 957-963
-
-
Mali, P.1
Esvelt, K.M.2
Church, G.M.3
-
5
-
-
36749058357
-
Engineers meet small RNA
-
Rusk N. Engineers meet small RNA. Nat Methods 2007, 4:986-987.
-
(2007)
Nat Methods
, vol.4
, pp. 986-987
-
-
Rusk, N.1
-
6
-
-
78651270582
-
TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
-
Li T., Huang S., Jiang W.Z., Wright D., Spalding M.H., Weeks D.P., Yang B. TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain. Nucleic Acids Res 2011, 39:359-372.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 359-372
-
-
Li, T.1
Huang, S.2
Jiang, W.Z.3
Wright, D.4
Spalding, M.H.5
Weeks, D.P.6
Yang, B.7
-
7
-
-
79960558872
-
Targeted genome editing across species using ZFNs and TALENs
-
Wood A.J., Lo T.-W., Zeitler B., Pickle C.S., Ralston E.J., Lee A.H., Amora R., Miller J.C., Leung E., Meng X., et al. Targeted genome editing across species using ZFNs and TALENs. Science 2011, 333:307.
-
(2011)
Science
, vol.333
, pp. 307
-
-
Wood, A.J.1
Lo, T.-W.2
Zeitler, B.3
Pickle, C.S.4
Ralston, E.J.5
Lee, A.H.6
Amora, R.7
Miller, J.C.8
Leung, E.9
Meng, X.10
-
8
-
-
79952302385
-
De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
-
Mahfouz M.M., Li L., Shamimuzzaman M., Wibowo A., Fang X., Zhu J.-K. De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks. Proc Natl Acad Sci U S A 2011, 108:2623-2628.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 2623-2628
-
-
Mahfouz, M.M.1
Li, L.2
Shamimuzzaman, M.3
Wibowo, A.4
Fang, X.5
Zhu, J.-K.6
-
9
-
-
78650739853
-
Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors
-
Morbitzer R., Römer P., Boch J., Lahaye T. Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors. Proc Natl Acad Sci U S A 2010, 107:21617-21622.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21617-21622
-
-
Morbitzer, R.1
Römer, P.2
Boch, J.3
Lahaye, T.4
-
10
-
-
79961185942
-
Heritable gene targeting in zebrafish using customized TALENs
-
Huang P., Xiao A., Zhou M.G., Zhu Z.Y., Lin S., Zhang B. Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol 2011, 29:699-700.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 699-700
-
-
Huang, P.1
Xiao, A.2
Zhou, M.G.3
Zhu, Z.Y.4
Lin, S.5
Zhang, B.6
-
11
-
-
79961192836
-
Targeted gene disruption in somatic zebrafish cells using engineered TALENs
-
Sander J.D., Cade L., Khayter C., Reyon D., Peterson R.T., Joung J.K., Yeh J.R.J. Targeted gene disruption in somatic zebrafish cells using engineered TALENs. Nat Biotechnol 2011, 29:697-698.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 697-698
-
-
Sander, J.D.1
Cade, L.2
Khayter, C.3
Reyon, D.4
Peterson, R.T.5
Joung, J.K.6
Yeh, J.R.J.7
-
12
-
-
84888866065
-
Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish
-
Hruscha A., Krawitz P., Rechenberg A., Heinrich V., Hecht J., Haass C., Schmid B. Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish. Development 2013, 140:4982-4987.
-
(2013)
Development
, vol.140
, pp. 4982-4987
-
-
Hruscha, A.1
Krawitz, P.2
Rechenberg, A.3
Heinrich, V.4
Hecht, J.5
Haass, C.6
Schmid, B.7
-
13
-
-
84888781186
-
Repurposing CRISPR/Cas9 for in situ functional assays
-
Malina A., Mills J.R., Cencic R., Yan Y., Fraser J., Schippers L.M., Paquet M., Dostie J., Pelletier J. Repurposing CRISPR/Cas9 for in situ functional assays. Genes Dev 2013, 27:2602-2614.
-
(2013)
Genes Dev
, vol.27
, pp. 2602-2614
-
-
Malina, A.1
Mills, J.R.2
Cencic, R.3
Yan, Y.4
Fraser, J.5
Schippers, L.M.6
Paquet, M.7
Dostie, J.8
Pelletier, J.9
-
14
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong L., Ran F.A., Cox D., Lin S., Barretto R., Habib N., Hsu P.D., Wu X., Jiang W., Marraffini L.A., et al. Multiplex genome engineering using CRISPR/Cas systems. Science 2013, 339:819-823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
-
15
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
Hockemeyer D., Wang H., Kiani S., Lai C.S., Gao Q., Cassady J.P., Cost G.J., Zhang L., Santiago Y., Miller J.C., et al. Genetic engineering of human pluripotent cells using TALE nucleases. Nat Biotechnol 2011, 29:731-734.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 731-734
-
-
Hockemeyer, D.1
Wang, H.2
Kiani, S.3
Lai, C.S.4
Gao, Q.5
Cassady, J.P.6
Cost, G.J.7
Zhang, L.8
Santiago, Y.9
Miller, J.C.10
-
16
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
Miller J.C., Tan S., Qiao G., Barlow K.A., Wang J., Xia D.F., Meng X., Paschon D.E., Leung E., Hinkley S.J., et al. A TALE nuclease architecture for efficient genome editing. Nat Biotechnol 2011, 29:143-148.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 143-148
-
-
Miller, J.C.1
Tan, S.2
Qiao, G.3
Barlow, K.A.4
Wang, J.5
Xia, D.F.6
Meng, X.7
Paschon, D.E.8
Leung, E.9
Hinkley, S.J.10
-
17
-
-
84870786425
-
Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression
-
Li Y., Moore R., Guinn M., Bleris L. Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression. Sci Rep 2012, 2:897.
-
(2012)
Sci Rep
, vol.2
, pp. 897
-
-
Li, Y.1
Moore, R.2
Guinn, M.3
Bleris, L.4
-
18
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali P., Yang L., Esvelt K.M., Aach J., Guell M., DiCarlo J.E., Norville J.E., Church G.M. RNA-guided human genome engineering via Cas9. Science 2013, 339:823-826.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
19
-
-
84884160273
-
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
-
Mali P., Aach J., Stranges P.B., Esvelt K.M., Moosburner M., Kosuri S., Yang L., Church G.M. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat Biotechnol 2013.
-
(2013)
Nat Biotechnol
-
-
Mali, P.1
Aach, J.2
Stranges, P.B.3
Esvelt, K.M.4
Moosburner, M.5
Kosuri, S.6
Yang, L.7
Church, G.M.8
-
20
-
-
84878936806
-
CRISPR-mediated adaptive immune systems in bacteria and archaea
-
Sorek R., Lawrence C.M., Wiedenheft B. CRISPR-mediated adaptive immune systems in bacteria and archaea. Annu Rev Biochem 2013, 82:237-266.
-
(2013)
Annu Rev Biochem
, vol.82
, pp. 237-266
-
-
Sorek, R.1
Lawrence, C.M.2
Wiedenheft, B.3
-
21
-
-
4344682527
-
The small RNA regulators of Escherichia coli: roles and mechanisms
-
Gottesman S. The small RNA regulators of Escherichia coli: roles and mechanisms. Annu Rev Microbiol 2004, 58:303-328.
-
(2004)
Annu Rev Microbiol
, vol.58
, pp. 303-328
-
-
Gottesman, S.1
-
22
-
-
77956126894
-
Xanthomonas AvrBs3 family-type III effectors: discovery and function
-
Boch J., Bonas U. Xanthomonas AvrBs3 family-type III effectors: discovery and function. Annu Rev Phytopathol 2010, 48:419-436.
-
(2010)
Annu Rev Phytopathol
, vol.48
, pp. 419-436
-
-
Boch, J.1
Bonas, U.2
-
24
-
-
84873522297
-
TAL effectors: function, structure, engineering and applications
-
Mak A.N.-S., Bradley P., Bogdanove A.J., Stoddard B.L. TAL effectors: function, structure, engineering and applications. Curr Opin Struct Biol 2013, 23:93-99.
-
(2013)
Curr Opin Struct Biol
, vol.23
, pp. 93-99
-
-
Mak, A.N.-S.1
Bradley, P.2
Bogdanove, A.J.3
Stoddard, B.L.4
-
25
-
-
72149110399
-
Breaking the code of DNA binding specificity of TAL-type III effectors
-
Boch J., Scholze H., Schornack S., Landgraf A., Hahn S., Kay S., Lahaye T., Nickstadt A., Bonas U. Breaking the code of DNA binding specificity of TAL-type III effectors. Science 2009, 326:1509-1512.
-
(2009)
Science
, vol.326
, pp. 1509-1512
-
-
Boch, J.1
Scholze, H.2
Schornack, S.3
Landgraf, A.4
Hahn, S.5
Kay, S.6
Lahaye, T.7
Nickstadt, A.8
Bonas, U.9
-
26
-
-
72149090954
-
A simple cipher governs DNA recognition by TAL effectors
-
Moscou M.J., Bogdanove A.J. A simple cipher governs DNA recognition by TAL effectors. Science 2009, 326:1501.
-
(2009)
Science
, vol.326
, pp. 1501
-
-
Moscou, M.J.1
Bogdanove, A.J.2
-
27
-
-
84883588736
-
Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism
-
Stella S., Molina R., Yefimenko I., Prieto J., Silva G., Bertonati C., Juillerat A., Duchateau P., Montoya G. Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism. Acta Crystallogr D Biol Crystallogr 2013, 69:1707-1716.
-
(2013)
Acta Crystallogr D Biol Crystallogr
, vol.69
, pp. 1707-1716
-
-
Stella, S.1
Molina, R.2
Yefimenko, I.3
Prieto, J.4
Silva, G.5
Bertonati, C.6
Juillerat, A.7
Duchateau, P.8
Montoya, G.9
-
28
-
-
84857032466
-
Structural basis for sequence-specific recognition of DNA by TAL effectors
-
Deng D., Yan C., Pan X., Mahfouz M., Wang J., Zhu J.-K., Shi Y., Yan N. Structural basis for sequence-specific recognition of DNA by TAL effectors. Science 2012, 335:720-723.
-
(2012)
Science
, vol.335
, pp. 720-723
-
-
Deng, D.1
Yan, C.2
Pan, X.3
Mahfouz, M.4
Wang, J.5
Zhu, J.-K.6
Shi, Y.7
Yan, N.8
-
29
-
-
84857029597
-
The crystal structure of TAL effector PthXo1 bound to its DNA target
-
Mak A.N., Bradley P., Cernadas R.A., Bogdanove A.J., Stoddard B.L. The crystal structure of TAL effector PthXo1 bound to its DNA target. Science 2012, 335:716-719.
-
(2012)
Science
, vol.335
, pp. 716-719
-
-
Mak, A.N.1
Bradley, P.2
Cernadas, R.A.3
Bogdanove, A.J.4
Stoddard, B.L.5
-
30
-
-
84876591961
-
Artificial repressors for controlling gene expression in bacteria
-
Politz M.C., Copeland M.F., Pfleger B.F. Artificial repressors for controlling gene expression in bacteria. Chem Commun (Camb) 2013, 49:4325-4327.
-
(2013)
Chem Commun (Camb)
, vol.49
, pp. 4325-4327
-
-
Politz, M.C.1
Copeland, M.F.2
Pfleger, B.F.3
-
31
-
-
0028960228
-
Inhibition of transcription initiation by lac repressor
-
Schlax P.J., Capp M.W., Record M.T. Inhibition of transcription initiation by lac repressor. J Mol Biol 1995, 245:331-350.
-
(1995)
J Mol Biol
, vol.245
, pp. 331-350
-
-
Schlax, P.J.1
Capp, M.W.2
Record, M.T.3
-
32
-
-
1842591130
-
The regulation of bacterial transcription initiation
-
Browning D.F., Busby S.J.W. The regulation of bacterial transcription initiation. Nat Rev Microbiol 2004, 2:57-65.
-
(2004)
Nat Rev Microbiol
, vol.2
, pp. 57-65
-
-
Browning, D.F.1
Busby, S.J.W.2
-
33
-
-
84890091231
-
Directed evolution of the TALE N-terminal domain for recognition of all 5' bases
-
Lamb B.M., Mercer A.C., Barbas C.F. Directed evolution of the TALE N-terminal domain for recognition of all 5' bases. Nucleic Acids Res 2013.
-
(2013)
Nucleic Acids Res
-
-
Lamb, B.M.1
Mercer, A.C.2
Barbas, C.F.3
-
34
-
-
84876557961
-
Quantitative analysis of TALE-DNA interactions suggests polarity effects
-
Meckler J.F., Bhakta M.S., Kim M.-S., Ovadia R., Habrian C.H., Zykovich A., Yu A., Lockwood S.H., Morbitzer R., Elsäesser J., et al. Quantitative analysis of TALE-DNA interactions suggests polarity effects. Nucleic Acids Res 2013, 41:4118-4128.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 4118-4128
-
-
Meckler, J.F.1
Bhakta, M.S.2
Kim, M.-S.3
Ovadia, R.4
Habrian, C.H.5
Zykovich, A.6
Yu, A.7
Lockwood, S.H.8
Morbitzer, R.9
Elsäesser, J.10
-
35
-
-
84866721599
-
Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues
-
Christian M.L., Demorest Z.L., Starker C.G., Osborn M.J., Nyquist M.D., Zhang Y., Carlson D.F., Bradley P., Bogdanove A.J., Voytas D.F. Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues. PLoS ONE 2012, 7:e45383.
-
(2012)
PLoS ONE
, vol.7
-
-
Christian, M.L.1
Demorest, Z.L.2
Starker, C.G.3
Osborn, M.J.4
Nyquist, M.D.5
Zhang, Y.6
Carlson, D.F.7
Bradley, P.8
Bogdanove, A.J.9
Voytas, D.F.10
-
36
-
-
84864856835
-
Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains
-
Cong L., Zhou R.H., Kuo Y.C., Cunniff M., Zhang F. Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Nat Commun 2012, 3.
-
(2012)
Nat Commun
, pp. 3
-
-
Cong, L.1
Zhou, R.H.2
Kuo, Y.C.3
Cunniff, M.4
Zhang, F.5
-
37
-
-
84863678546
-
TAL effector RVD specificities and efficiencies
-
Streubel J., Blücher C., Landgraf A., Boch J. TAL effector RVD specificities and efficiencies. Nat Biotechnol 2012, 30:593-595.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 593-595
-
-
Streubel, J.1
Blücher, C.2
Landgraf, A.3
Boch, J.4
-
38
-
-
79751487297
-
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
-
Zhang F., Cong L., Lodato S., Kosuri S., Church G.M., Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nat Biotechnol 2011, 29:149-153.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 149-153
-
-
Zhang, F.1
Cong, L.2
Lodato, S.3
Kosuri, S.4
Church, G.M.5
Arlotta, P.6
-
40
-
-
84885879232
-
A ligation-independent cloning technique for high-throughput assembly of transcription activator-like effector genes
-
Schmid-Burgk J.L., Schmidt T., Kaiser V., Höning K., Hornung V. A ligation-independent cloning technique for high-throughput assembly of transcription activator-like effector genes. Nat Biotechnol 2012.
-
(2012)
Nat Biotechnol
-
-
Schmid-Burgk, J.L.1
Schmidt, T.2
Kaiser, V.3
Höning, K.4
Hornung, V.5
-
41
-
-
84866879789
-
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers
-
Briggs A.W., Rios X., Chari R., Yang L., Zhang F., Mali P., Church G.M. Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res 2012.
-
(2012)
Nucleic Acids Res
-
-
Briggs, A.W.1
Rios, X.2
Chari, R.3
Yang, L.4
Zhang, F.5
Mali, P.6
Church, G.M.7
-
43
-
-
74249095519
-
CRISPR/Cas, the immune system of bacteria and Archaea
-
Horvath P., Barrangou R. CRISPR/Cas, the immune system of bacteria and Archaea. Science 2010, 327:167-170.
-
(2010)
Science
, vol.327
, pp. 167-170
-
-
Horvath, P.1
Barrangou, R.2
-
44
-
-
84857097177
-
RNA-guided genetic silencing systems in bacteria and archaea
-
Wiedenheft B., Sternberg S.H., Doudna J.A. RNA-guided genetic silencing systems in bacteria and archaea. Nature 2012, 482:331-338.
-
(2012)
Nature
, vol.482
, pp. 331-338
-
-
Wiedenheft, B.1
Sternberg, S.H.2
Doudna, J.A.3
-
45
-
-
79953250082
-
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
-
Deltcheva E., Chylinski K., Sharma C.M., Gonzales K., Chao Y., Pirzada Z.A., Eckert M.R., Vogel J., Charpentier E. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature 2011, 471:602-607.
-
(2011)
Nature
, vol.471
, pp. 602-607
-
-
Deltcheva, E.1
Chylinski, K.2
Sharma, C.M.3
Gonzales, K.4
Chao, Y.5
Pirzada, Z.A.6
Eckert, M.R.7
Vogel, J.8
Charpentier, E.9
-
46
-
-
84884906690
-
RNA-guided gene activation by CRISPR-Cas9-based transcription factors
-
Perez-Pinera P., Kocak D.D., Vockley C.M., Adler A.F., Kabadi A.M., Polstein L.R., Thakore P.I., Glass K.A., Ousterout D.G., Leong K.W., et al. RNA-guided gene activation by CRISPR-Cas9-based transcription factors. Nat Methods 2013, 10:973-976.
-
(2013)
Nat Methods
, vol.10
, pp. 973-976
-
-
Perez-Pinera, P.1
Kocak, D.D.2
Vockley, C.M.3
Adler, A.F.4
Kabadi, A.M.5
Polstein, L.R.6
Thakore, P.I.7
Glass, K.A.8
Ousterout, D.G.9
Leong, K.W.10
-
47
-
-
84884907424
-
CRISPR RNA-guided activation of endogenous human genes
-
Maeder M.L., Linder S.J., Cascio V.M., Fu Y., Ho Q.H., Joung J.K. CRISPR RNA-guided activation of endogenous human genes. Nat Methods 2013, 10:977-979.
-
(2013)
Nat Methods
, vol.10
, pp. 977-979
-
-
Maeder, M.L.1
Linder, S.J.2
Cascio, V.M.3
Fu, Y.4
Ho, Q.H.5
Joung, J.K.6
-
48
-
-
84874687019
-
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
-
Qi L.S., Larson M.H., Gilbert L.A., Doudna J.A., Weissman J.S., Arkin A.P., Lim W.A. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 2013, 152:1173-1183.
-
(2013)
Cell
, vol.152
, pp. 1173-1183
-
-
Qi, L.S.1
Larson, M.H.2
Gilbert, L.A.3
Doudna, J.A.4
Weissman, J.S.5
Arkin, A.P.6
Lim, W.A.7
-
49
-
-
84882986957
-
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system
-
Bikard D., Jiang W., Samai P., Hochschild A., Zhang F., Marraffini L.A. Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Res 2013.
-
(2013)
Nucleic Acids Res
-
-
Bikard, D.1
Jiang, W.2
Samai, P.3
Hochschild, A.4
Zhang, F.5
Marraffini, L.A.6
-
50
-
-
84865070369
-
DNA programmable dual-RNA-guided, endonuclease in adaptive bacterial immunity
-
Jinek M., Chylinski K., Fonfara I., Hauer M., Doudna J.A., Charpentier E: A. DNA programmable dual-RNA-guided, endonuclease in adaptive bacterial immunity. Science 2012, 337:816-821.
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.A.6
-
51
-
-
84886993480
-
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
-
Larson M.H., Gilbert L.A., Wang X., Lim W.A., Weissman J.S., Qi L.S. CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nat Protoc 2013, 8:2180-2196.
-
(2013)
Nat Protoc
, vol.8
, pp. 2180-2196
-
-
Larson, M.H.1
Gilbert, L.A.2
Wang, X.3
Lim, W.A.4
Weissman, J.S.5
Qi, L.S.6
-
52
-
-
64049118040
-
Short motif sequences determine the targets of the prokaryotic CRISPR defence system
-
Mojica F.J., Diez-Villasenor C., Garcia-Martinez J., Almendros C. Short motif sequences determine the targets of the prokaryotic CRISPR defence system. Microbiology 2009, 155:733-740.
-
(2009)
Microbiology
, vol.155
, pp. 733-740
-
-
Mojica, F.J.1
Diez-Villasenor, C.2
Garcia-Martinez, J.3
Almendros, C.4
-
53
-
-
79959963663
-
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
-
Semenova E., Jore M.M., Datsenko K.A., Semenova A., Westra E.R., Wanner B., van der Oost J., Brouns S.J., Severinov K. Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence. Proc Natl Acad Sci U S A 2011, 108:10098-10103.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 10098-10103
-
-
Semenova, E.1
Jore, M.M.2
Datsenko, K.A.3
Semenova, A.4
Westra, E.R.5
Wanner, B.6
van der Oost, J.7
Brouns, S.J.8
Severinov, K.9
-
54
-
-
84884161677
-
Staying on target with CRISPR-Cas
-
Carroll D. Staying on target with CRISPR-Cas. Nat Biotech 2013, 31:807-809.
-
(2013)
Nat Biotech
, vol.31
, pp. 807-809
-
-
Carroll, D.1
-
55
-
-
20644462362
-
Micros for microbes: non-coding regulatory RNAs in bacteria
-
Gottesman S. Micros for microbes: non-coding regulatory RNAs in bacteria. Trends Genet 2005, 21:399-404.
-
(2005)
Trends Genet
, vol.21
, pp. 399-404
-
-
Gottesman, S.1
-
56
-
-
84875457350
-
Bacterial small RNA-based negative regulation: Hfq and its accomplices
-
De Lay N., Schu D.J., Gottesman S. Bacterial small RNA-based negative regulation: Hfq and its accomplices. J Biol Chem 2013, 288:7996-8003.
-
(2013)
J Biol Chem
, vol.288
, pp. 7996-8003
-
-
De Lay, N.1
Schu, D.J.2
Gottesman, S.3
-
57
-
-
35548995356
-
The RNA degradosome of Escherichia coli: an mRNA-degrading machine assembled on RNase E
-
Carpousis A.J. The RNA degradosome of Escherichia coli: an mRNA-degrading machine assembled on RNase E. Annu Rev Microbiol 2007, 61:71-87.
-
(2007)
Annu Rev Microbiol
, vol.61
, pp. 71-87
-
-
Carpousis, A.J.1
-
58
-
-
0036440529
-
Identification of essential genes in Staphylococcus aureus using inducible antisense RNA
-
Ji Y., Woodnutt G., Rosenberg M., Burnham M.K.R. Identification of essential genes in Staphylococcus aureus using inducible antisense RNA. Methods Enzymol 2002, 358:123-128.
-
(2002)
Methods Enzymol
, vol.358
, pp. 123-128
-
-
Ji, Y.1
Woodnutt, G.2
Rosenberg, M.3
Burnham, M.K.R.4
-
59
-
-
84872401866
-
Knockdown of recA gene expression by artificial small RNAs in Escherichia coli
-
Sharma V., Sakai Y., Smythe K.A., Yokobayashi Y. Knockdown of recA gene expression by artificial small RNAs in Escherichia coli. Biochem Biophys Res Commun 2013, 430:256-259.
-
(2013)
Biochem Biophys Res Commun
, vol.430
, pp. 256-259
-
-
Sharma, V.1
Sakai, Y.2
Smythe, K.A.3
Yokobayashi, Y.4
-
60
-
-
84856536610
-
Small RNA RyhB as a potential tool used for metabolic engineering in Escherichia coli
-
Kang Z., Wang X., Li Y., Wang Q., Qi Q. Small RNA RyhB as a potential tool used for metabolic engineering in Escherichia coli. Biotechnol Lett 2012, 34:527-531.
-
(2012)
Biotechnol Lett
, vol.34
, pp. 527-531
-
-
Kang, Z.1
Wang, X.2
Li, Y.3
Wang, Q.4
Qi, Q.5
-
61
-
-
0037337740
-
Design of antisense RNA constructs for downregulation of the acetone formation pathway of Clostridium acetobutylicum
-
Tummala S.B., Welker N.E., Papoutsakis E.T. Design of antisense RNA constructs for downregulation of the acetone formation pathway of Clostridium acetobutylicum. J Bacteriol 2003, 185:1923-1934.
-
(2003)
J Bacteriol
, vol.185
, pp. 1923-1934
-
-
Tummala, S.B.1
Welker, N.E.2
Papoutsakis, E.T.3
-
62
-
-
84873596341
-
Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs
-
Na D., Yoo S.M., Chung H., Park H., Park J.H., Lee S.Y. Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs. Nat Biotechnol 2013, 31:170-174.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 170-174
-
-
Na, D.1
Yoo, S.M.2
Chung, H.3
Park, H.4
Park, J.H.5
Lee, S.Y.6
-
63
-
-
84867191934
-
Engineering artificial small RNAs for conditional gene silencing in Escherichia coli
-
Sharma V., Yamamura A., Yokobayashi Y. Engineering artificial small RNAs for conditional gene silencing in Escherichia coli. ACS Synth Biol 2012, 1:6-13.
-
(2012)
ACS Synth Biol
, vol.1
, pp. 6-13
-
-
Sharma, V.1
Yamamura, A.2
Yokobayashi, Y.3
-
64
-
-
79955607368
-
Artificial trans-encoded small non-coding RNAs specifically silence the selected gene expression in bacteria
-
Man S., Cheng R., Miao C., Gong Q., Gu Y., Lu X., Han F., Yu W. Artificial trans-encoded small non-coding RNAs specifically silence the selected gene expression in bacteria. Nucleic Acids Res 2011, 39:e50.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Man, S.1
Cheng, R.2
Miao, C.3
Gong, Q.4
Gu, Y.5
Lu, X.6
Han, F.7
Yu, W.8
-
65
-
-
84883419083
-
Design and use of synthetic regulatory small RNAs to control gene expression in Escherichia coli
-
Yoo S.M., Na D., Lee S.Y. Design and use of synthetic regulatory small RNAs to control gene expression in Escherichia coli. UNKNOWN 2013, 8:1694-1707.
-
(2013)
UNKNOWN
, vol.8
, pp. 1694-1707
-
-
Yoo, S.M.1
Na, D.2
Lee, S.Y.3
-
66
-
-
79951540365
-
The stoichiometry of the Escherichia coli Hfq protein bound to RNA
-
Updegrove T.B., Correia J.J., Chen Y., Terry C., Wartell R.M. The stoichiometry of the Escherichia coli Hfq protein bound to RNA. RNA 2011, 17:489-500.
-
(2011)
RNA
, vol.17
, pp. 489-500
-
-
Updegrove, T.B.1
Correia, J.J.2
Chen, Y.3
Terry, C.4
Wartell, R.M.5
-
67
-
-
84874616818
-
Synergistic and tunable human gene activation by combinations of synthetic transcription factors
-
Perez-Pinera P., Ousterout D.G., Brunger J.M., Farin A.M., Glass K.A., Guilak F., Crawford G.E., Hartemink A.J., Gersbach C.A. Synergistic and tunable human gene activation by combinations of synthetic transcription factors. Nat Methods 2013, 10:239-242.
-
(2013)
Nat Methods
, vol.10
, pp. 239-242
-
-
Perez-Pinera, P.1
Ousterout, D.G.2
Brunger, J.M.3
Farin, A.M.4
Glass, K.A.5
Guilak, F.6
Crawford, G.E.7
Hartemink, A.J.8
Gersbach, C.A.9
-
68
-
-
84867389802
-
RNA processing enables predictable programming of gene expression
-
1002-+
-
Qi L., Haurwitz R.E., Shao W.J., Doudna J.A., Arkin A.P. RNA processing enables predictable programming of gene expression. Nat Biotechnol 2012, 30. 1002-+.
-
(2012)
Nat Biotechnol
, vol.30
-
-
Qi, L.1
Haurwitz, R.E.2
Shao, W.J.3
Doudna, J.A.4
Arkin, A.P.5
-
69
-
-
84887104139
-
Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
-
Esvelt K.M., Mali P., Braff J.L., Moosburner M., Yaung S.J., Church G.M. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nat Methods 2013, 10:1116-1121.
-
(2013)
Nat Methods
, vol.10
, pp. 1116-1121
-
-
Esvelt, K.M.1
Mali, P.2
Braff, J.L.3
Moosburner, M.4
Yaung, S.J.5
Church, G.M.6
-
70
-
-
34548668642
-
Quantitative characteristics of gene regulation by small RNA
-
Levine E., Zhang Z., Kuhlman T., Hwa T. Quantitative characteristics of gene regulation by small RNA. PLoS Biol 2007, 5:1998-2010.
-
(2007)
PLoS Biol
, vol.5
, pp. 1998-2010
-
-
Levine, E.1
Zhang, Z.2
Kuhlman, T.3
Hwa, T.4
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