Spinal transient receptor potential ankyrin 1 channel induces mechanical hypersensitivity, increases cutaneous blood flow, and mediates the pronociceptive action of dynorphin A

Journal of Physiology and Pharmacology

Volumn 64, Issue 3, 2013, Pages

  Wei, H ^a   Saarnilehto, M ^b   Falck, L ^b   Viisanen, H ^a   Lasierra, M ^a   Koivisto, A ^b   Pertovaara, Antti ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b ORION CORPORATION   (Finland)

Author keywords

Blood flow; Cinnamaldehyde; Cutaneous circulation; Dynorphin A; Pain hypersensitivity; Spinal dorsal horn; Transient receptor potential ankyrin 1

Indexed keywords

A 967079; BICUCULLINE; CARBENOXOLONE; CHEMBRIDGE 5861528; CHOLECYSTOKININ; CINNAMALDEHYDE; DIZOCILPINE; DYNORPHIN A; MINOCYCLINE; PROSTAGLANDIN F2 ALPHA; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL AFFECTING AGENT; UNCLASSIFIED DRUG; ACROLEIN; ANALGESIC AGENT; DYNORPHIN; NERVE PROTEIN; OXIME; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRPA1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDROMIC STIMULATION; ANTINOCICEPTION; ARTICLE; BEHAVIORAL SCIENCE; CELL ACTIVATION; CONTROLLED STUDY; DRUG MECHANISM; GAP JUNCTION; HEAT SENSITIVITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MECHANICAL PAIN HYPERSENSITIVITY; MICROGLIA; MOLECULAR INTERACTION; NEUROGENIC INFLAMMATION; NOCICEPTION; NONHUMAN; PAIN ASSESSMENT; RAT; SENSORY NERVE; SKIN BLOOD FLOW; SYNAPTIC TRANSMISSION; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL BEHAVIOR; ANTAGONISTS AND INHIBITORS; BACK PAIN; BLOOD FLOW; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; HYPERALGESIA; INTRASPINAL DRUG ADMINISTRATION; METABOLISM; POSTERIOR HORN CELL; SKIN; STIMULATION; VASCULARIZATION; WISTAR RAT;

ACROLEIN; ANALGESICS, NON-NARCOTIC; ANIMALS; BACK PAIN; BEHAVIOR, ANIMAL; CHOLECYSTOKININ; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; DYNORPHINS; HYPERALGESIA; INJECTIONS, SPINAL; MALE; MINOCYCLINE; NERVE TISSUE PROTEINS; OXIMES; PHYSICAL STIMULATION; POSTERIOR HORN CELLS; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; SKIN; TRPC CATION CHANNELS;

EID: 84895914733     PISSN: 08675910     EISSN: 18991505     Source Type: Journal    
DOI: None     Document Type: Article

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