Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E 2 in the spinal cord

Pain

Volumn 153, Issue 1, 2012, Pages 86-94

  Marshall, Timothy M ^a   Herman, David S ^a,b   Largent Milnes, Tally M ^a   Badghisi, Hamid ^a   Zuber, Konstantina ^a,c   Holt, Shannon C ^a   Lai, Josephine ^a   Porreca, Frank ^a   Vanderah, Todd W ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b Cephalon   (United States)

^c ADVOCATE CHRIST MEDICAL CENTER   (United States)

Author keywords

Cholecystokinin; Descending facilitation; Microdialysis; Nerve injury; PGE 2; Rostral ventromedial medulla; Serotonin; Tactile hypersensitivity

Indexed keywords

1 [2,3 DIHYDRO 1 (2' METHYLPHENACYL) 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL] 3 (3 METHYLPHENYL)UREA; 5 HYDROXYINDOLEACETIC ACID; CHOLECYSTOKININ; NAPROXEN; ONDANSETRON; PROSTAGLANDIN E2; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG ACTIVITY; HYPERSENSITIVITY; LUMBAR SPINAL CORD; MALE; MICRODIALYSIS; NERVE INJURY; NERVE LIGATION; NONHUMAN; PAIN PARAMETERS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; ROSTRAL VENTROMEDIAL MEDULLA; SPINAL CORD; SPINAL NERVE; TACTILE STIMULATION;

ANIMALS; CHOLECYSTOKININ; DINOPROSTONE; HYPERALGESIA; MALE; MEDULLA OBLONGATA; PAIN; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL NERVES;

EID: 84155170905     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2011.09.021     Document Type: Article

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