MiR-342-5p decreases ankyrin G levels in Alzheimer's disease transgenic mouse models

Cell Reports

Volumn 6, Issue 2, 2014, Pages 264-270

  Sun, Xiaqin ^a   Wu, Yu ^a   Gu, Mingxue ^a   Zhang, Yan ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANKYRINS; AXONS; BETA CATENIN; CELLS, CULTURED; HUMANS; INTERFERON-STIMULATED GENE FACTOR 3, GAMMA SUBUNIT; MICE; MICRORNAS; PRESENILIN-1; PROTO-ONCOGENE PROTEINS C-MYC;

ANKYRIN; ANKYRIN G; BETA CATENIN; INTERFERON REGULATORY FACTOR 9; MESSENGER RNA; MICRORNA; MIR 342 5P; MYC PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; MOLECULAR PATHOLOGY; MOUSE; NEUROPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

MUS; MUS MUSCULUS;

EID: 84895907973     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.12.028     Document Type: Article

References (50)

1. Ashraf S.I., McLoon A.L., Sclarsic S.M., Kunes S. Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila. Cell 2006, 124:191-205.
2. Baek D., Villén J., Shin C., Camargo F.D., Gygi S.P., Bartel D.P. The impact of microRNAs on protein output. Nature 2008, 455:64-71.
3. Bayer T.A., Wirths O., Majtényi K., Hartmann T., Multhaup G., Beyreuther K., Czech C. Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport. Brain Pathol. 2001, 11:1-11.
4. Bennett V., Chen L. Ankyrins and cellular targeting of diverse membrane proteins to physiological sites. Curr. Opin. Cell Biol. 2001, 13:61-67.
5. Buffington S.A., Rasband M.N. The axon initial segment in nervous system disease and injury. Eur. J. Neurosci. 2011, 34:1609-1619.
6. Chan A.W., Kocerha J. The path to microRNA therapeutics in psychiatric and neurodegenerative disorders. Front Genet 2012, 3:82.
7. Cogswell J.P., Ward J., Taylor I.A., Waters M., Shi Y., Cannon B., Kelnar K., Kemppainen J., Brown D., Chen C., et al. Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J.Alzheimers Dis. 2008, 14:27-41.
8. Cui J., Wang Y., Dong Q., Wu S., Xiao X., Hu J., Chai Z., Zhang Y. Morphine protects against intracellular amyloid toxicity by inducing estradiol release and upregulation of Hsp70. J.Neurosci. 2011, 31:16227-16240.
9. De Marchis M.L., Ballarino M., Salvatori B., Puzzolo M.C., Bozzoni I., Fatica A. A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells. Leukemia 2009, 23:856-862.
10. Delay C., Hébert S.S. MicroRNAs and Alzheimer's disease mouse models: current insights and future research avenues. Int. J. Alzheimers Dis. 2011, 2011:894938.
11. Delay C., Mandemakers W., Hébert S.S. MicroRNAs in Alzheimer's disease. Neurobiol. Dis. 2012, 46:285-290.
12. Elmén J., Lindow M., Schütz S., Lawrence M., Petri A., Obad S., Lindholm M., Hedtjärn M., Hansen H.F., Berger U., et al. LNA-mediated microRNA silencing in non-human primates. Nature 2008, 452:896-899.
13. Eulalio A., Huntzinger E., Nishihara T., Rehwinkel J., Fauser M., Izaurralde E. Deadenylation is a widespread effect of miRNA regulation. RNA 2009, 15:21-32.
14. Grady W.M., Parkin R.K., Mitchell P.S., Lee J.H., Kim Y.H., Tsuchiya K.D., Washington M.K., Paraskeva C., Willson J.K., Kaz A.M., et al. Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer. Oncogene 2008, 27:3880-3888.
15. Hébert S.S., Horré K., Nicolaï L., Papadopoulou A.S., Mandemakers W., Silahtaroglu A.N., Kauppinen S., Delacourte A., De Strooper B. Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc. Natl. Acad. Sci. USA 2008, 105:6415-6420.
16. Hedstrom K.L., Ogawa Y., Rasband M.N. AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity. J.Cell Biol. 2008, 183:635-640.
17. Hollander J.A., Im H.I., Amelio A.L., Kocerha J., Bali P., Lu Q., Willoughby D., Wahlestedt C., Conkright M.D., Kenny P.J. Striatal microRNA controls cocaine intake through CREB signalling. Nature 2010, 466:197-202.
18. Jin P., Zarnescu D.C., Ceman S., Nakamoto M., Mowrey J., Jongens T.A., Nelson D.L., Moses K., Warren S.T. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat. Neurosci. 2004, 7:113-117.
19. Kapfhamer D., Miller D.E., Lambert S., Bennett V., Glover T.W., Burmeister M. Chromosomal localization of the ankyrinG gene (ANK3/Ank3) to human 10q21 and mouse 10. Genomics 1995, 27:189-191.
20. Kordeli E., Lambert S., Bennett V. AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier. J.Biol. Chem. 1995, 270:2352-2359.
21. Krichevsky A.M., King K.S., Donahue C.P., Khrapko K., Kosik K.S. A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 2003, 9:1274-1281.
22. Lagos-Quintana M., Rauhut R., Lendeckel W., Tuschl T. Identification of novel genes coding for small expressed RNAs. Science 2001, 294:853-858.
23. Lazarov O., Morfini G.A., Pigino G., Gadadhar A., Chen X., Robinson J., Ho H., Brady S.T., Sisodia S.S. Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1. J.Neurosci. 2007, 27:7011-7020.
24. Li Y.Y., Cui J.G., Hill J.M., Bhattacharjee S., Zhao Y., Lukiw W.J. Increased expression of miRNA-146a in Alzheimer's disease transgenic mouse models. Neurosci. Lett. 2011, 487:94-98.
25. Lukiw W.J. Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 2007, 18:297-300.
26. Lukiw W.J., Zhao Y., Cui J.G. An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells. J.Biol. Chem. 2008, 283:31315-31322.
27. Meister G. miRNAs get an early start on translational silencing. Cell 2007, 131:25-28.
28. Nelson P.T., Wang W.X. MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study. J.Alzheimers Dis. 2010, 21:75-79.
29. Nunez-Iglesias J., Liu C.C., Morgan T.E., Finch C.E., Zhou X.J. Joint genome-wide profiling of miRNA and mRNA expression in Alzheimer's disease cortex reveals altered miRNA regulation. PLoS ONE 2010, 5:e8898.
30. Pan Z., Kao T., Horvath Z., Lemos J., Sul J.Y., Cranstoun S.D., Bennett V., Scherer S.S., Cooper E.C. A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon. J.Neurosci. 2006, 26:2599-2613.
31. Peters L., Meister G. Argonaute proteins: mediators of RNA silencing. Mol. Cell 2007, 26:611-623.
32. Price D.L., Sisodia S.S., Gandy S.E. Amyloid beta amyloidosis in Alzheimer's disease. Curr. Opin. Neurol. 1995, 8:268-274.
33. Rasband M.N. The axon initial segment and the maintenance of neuronal polarity. Nat. Rev. Neurosci. 2010, 11:552-562.
34. Roy S., Zhang B., Lee V.M., Trojanowski J.Q. Axonal transport defects: a common theme in neurodegenerative diseases. Acta Neuropathol. 2005, 109:5-13.
35. Schafer D.P., Jha S., Liu F., Akella T., McCullough L.D., Rasband M.N. Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury. J.Neurosci. 2009, 29:13242-13254.
36. Schipper H.M., Maes O.C., Chertkow H.M., Wang E. MicroRNA expression in Alzheimer blood mononuclear cells. Gene Regul Syst Bio 2007, 1:263-274.
37. Seitz V., Butzhammer P., Hirsch B., Hecht J., Gütgemann I., Ehlers A., Lenze D., Oker E., Sommerfeld A., von der Wall E., et al. Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma. PLoS ONE 2011, 6:e26837.
38. Selbach M., Schwanhäusser B., Thierfelder N., Fang Z., Khanin R., Rajewsky N. Widespread changes in protein synthesis induced by microRNAs. Nature 2008, 455:58-63.
39. Shioya M., Obayashi S., Tabunoki H., Arima K., Saito Y., Ishida T., Satoh J. Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3. Neuropathol. Appl. Neurobiol. 2010, 36:320-330.
40. Smalley M.J., Dale T.C. Wnt signalling in mammalian development and cancer. Cancer Metastasis Rev. 1999, 18:215-230.
41. Sobotzik J.M., Sie J.M., Politi C., Del Turco D., Bennett V., Deller T., Schultz C. AnkyrinG is required to maintain axo-dendritic polarity invivo. Proc. Natl. Acad. Sci. USA 2009, 106:17564-17569.
42. Song A.H., Wang D., Chen G., Li Y., Luo J., Duan S., Poo M.M. A selective filter for cytoplasmic transport at the axon initial segment. Cell 2009, 136:1148-1160.
43. Soriano S., Kang D.E., Fu M., Pestell R., Chevallier N., Zheng H., Koo E.H. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing. J.Cell Biol. 2001, 152:785-794.
44. Szu-Yu Ho T., Rasband M.N. Maintenance of neuronal polarity. Dev. Neurobiol. 2011, 71:474-482.
45. Wang W.X., Rajeev B.W., Stromberg A.J., Ren N., Tang G., Huang Q., Rigoutsos I., Nelson P.T. The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J.Neurosci. 2008, 28:1213-1223.
46. Wang X., Liu P., Zhu H., Xu Y., Ma C., Dai X., Huang L., Liu Y., Zhang L., Qin C. miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation. Brain Res. Bull. 2009, 80:268-273.
47. Westholm J.O., Lai E.C. Mirtrons: microRNA biogenesis via splicing. Biochimie 2011, 93:1897-1904.
48. Wirths O., Weis J., Szczygielski J., Multhaup G., Bayer T.A. Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer's disease. Acta Neuropathol. 2006, 111:312-319.
49. Yagishita S. Morphological investigations on axonal swellings and spheroids in various human diseases. Virchows Arch. A Pathol. Anat. Histol. 1978, 378:181-197.
50. Yao J., Hennessey T., Flynt A., Lai E., Beal M.F., Lin M.T. MicroRNA-related cofilin abnormality in Alzheimer's disease. PLoS ONE 2010, 5:e15546.