A high-content, multiplexed screen in human breast cancer cells identifies profilin-1 inducers with anti-migratory activities

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Joy, Marion E ^a   Vollmer, Laura L ^c   Hulkower, Keren ^e,f   Stern, Andrew M ^b,c   Peterson, Cameron K ^c   Boltz, R C ^b,c   Roy, Partha ^a,b,d   Vogt, Andreas ^b,c  

^a University of Pittsburgh   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e Platypus Technologies LLC   (United States)

^f North Carolina   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMETASTATIC AGENT; CYTOCHALASIN D; PROFILIN; PROFILIN I; PURVALANOL; SMALL INTERFERING RNA; TYRPHOSTIN A9; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL ASSAY; CELL MIGRATION; CELL MOTILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG SCREENING; GENE SILENCING; HUMAN; HUMAN CELL; METASTASIS INHIBITION; PROTEIN EXPRESSION; PROTEIN INDUCTION; UPREGULATION; WESTERN BLOTTING;

ADENINE; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MIGRATION ASSAYS; CELL MOVEMENT; FEMALE; GENE KNOCKDOWN TECHNIQUES; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; PROFILINS; REPRODUCIBILITY OF RESULTS; SMALL MOLECULE LIBRARIES; TYRPHOSTINS;

EID: 84895811941     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088350     Document Type: Article

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