Effect of diet on expression of genes involved in lipid metabolism, oxidative stress, and inflammation in mouse liver-insights into mechanisms of hepatic steatosis

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Renaud, Helen J ^a   Cui, Julia Y ^a   Lu, Hong ^b   Klaassen, Curtis D ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; FRUCTOSE; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROGENIC DIET; BILE ACID SYNTHESIS; CHOLESTEROL DIET; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DIET RESTRICTION; DIETARY INTAKE; FATTY ACID METABOLISM; FATTY LIVER; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ANALYSIS; GLUTATHIONE METABOLISM; HEPATITIS; IMMUNE RESPONSE; LIPID DIET; LIPID METABOLISM; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRINCIPAL COMPONENT ANALYSIS; SUGAR INTAKE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOSYNTHETIC PATHWAYS; CHOLESTEROL; CLUSTER ANALYSIS; DIET; FATTY ACIDS; FATTY LIVER; GENE EXPRESSION REGULATION; HOMEOSTASIS; INFLAMMATION; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PRINCIPAL COMPONENT ANALYSIS; SIGNAL TRANSDUCTION; SOFTWARE; TRANSCRIPTOME;

EID: 84895797524     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088584     Document Type: Article

References (60)

1. Agatston AS (2005) The end of the diet debates? All fats and carbs are not created equal. Cleve Clin J Med 72: 946-950.
2. Cordain L, Eaton SB, Sebastian A, Mann N, Lindeberg S, et al. (2005) Origins and evolution of the Western diet: health implications for the 21st century. Am J Clin Nutr 81: 341-354. (Pubitemid 43078368)
3. Siri-Tarino PW, Sun Q, Hu FB, Krauss RM (2010) Saturated fat, carbohydrate, and cardiovascular disease. Am J Clin Nutr 91: 502-509.
4. Moussavi N, Gavino V, Receveur O (2008) Could the quality of dietary fat, and not just its quantity, be related to risk of obesity? Obesity (Silver Spring) 16: 7-15. (Pubitemid 351271943)
5. Poudyal H, Panchal SK, Ward LC, Waanders J, Brown L (2012) Chronic high-carbohydrate, high-fat feeding in rats induces reversible metabolic, cardiovascular, and liver changes. Am J Physiol Endocrinol Metab 302: E1472-1482.
6. Tiniakos DG, Vos MB, Brunt EM (2010) Nonalcoholic fatty liver disease: pathology and pathogenesis. Annu Rev Pathol 5: 145-171.
7. Holloszy JO, Fontana L (2007) Caloric restriction in humans. Exp Gerontol 42: 709-712. (Pubitemid 47058857)
8. Schenk S, McCurdy CE, Philp A, Chen MZ, Holliday MJ, et al. (2011) Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J Clin Invest 121: 4281-4288.
9. Cordain L, Eades MR, Eades MD (2003) Hyperinsulinemic diseases of civilization: more than just Syndrome X. Comp Biochem Physiol A Mol Integr Physiol 136: 95-112. (Pubitemid 37289410)
10. Esposito K, Chiodini P, Colao A, Lenzi A, Giugliano D (2012) Metabolic syndrome and risk of cancer: a systematic review and meta-analysis. Diabetes Care 35: 2402-2411.
11. Mozumdar A, Liguori G (2011) Persistent increase of prevalence of metabolic syndrome among U.S. adults: NHANES III to NHANES 1999-2006. Diabetes Care 34: 216-219.
12. Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, et al. (2001) Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 50: 1844-1850. (Pubitemid 33641605)
13. Marchesini G, Moscatiello S, Di Domizio S, Forlani G (2008) Obesity-associated liver disease. J Clin Endocrinol Metab 93: S74-80.
14. Farrell GC, Larter CZ (2006) Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 43: S99-S112.
15. Saadeh S (2007) Nonalcoholic Fatty liver disease and obesity. Nutr Clin Pract 22: 1-10.
16. Day CP, James OF (1998) Steatohepatitis: a tale of two "hits"? Gastroenterology 114: 842-845.
17. Salt WB 2nd (2004) Nonalcoholic fatty liver disease (NAFLD): a comprehensive review. J Insur Med 36: 27-41.
18. Allard JP, Aghdassi E, Mohammed S, Raman M, Avand G, et al. (2008) Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD): a cross-sectional study. J Hepatol 48: 300-307.
19. Sanyal AJ, Campbell-Sargent C, Mirshahi F, Rizzo WB, Contos MJ, et al. (2001) Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 120: 1183-1192. (Pubitemid 32246672)
20. Levant B, Ozias MK, Carlson SE (2006) Diet (n-3) polyunsaturated fatty acid content and parity interact to alter maternal rat brain phospholipid fatty acid composition. J Nutr 136: 2236-2242. (Pubitemid 44156831)
21. Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al. (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80.
22. Smyth GK, Michaud J, Scott HS (2005) Use of within-array replicate spots for assessing differential expression in microarray experiments. Bioinformatics 21: 2067-2075. (Pubitemid 40668046)
23. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102: 15545-15550. (Pubitemid 41528093)
24. Raychaudhuri S, Stuart JM, Altman RB (2000) Principal components analysis to summarize microarray experiments: application to sporulation time series. Pac Symp Biocomput: 455-466.
25. Schneider CA, Rasband WS, Eliceiri KW (2012) NIH Image to ImageJ: 25 years of image analysis. Nat Methods 9: 671-675.
26. Atshaves BP, Martin GG, Hostetler HA, McIntosh AL, Kier AB, et al. (2010) Liver fatty acid-binding protein and obesity. J Nutr Biochem 21: 1015-1032.
27. Storch J, Corsico B (2008) The emerging functions and mechanisms of mammalian fatty acid-binding proteins. Annu Rev Nutr 28: 73-95.
28. Maeda K, Cao H, Kono K, Gorgun CZ, Furuhashi M, et al. (2005) Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metab 1: 107-119. (Pubitemid 43960591)
29. Bu L, Salto LM, De Leon KJ, De Leon M (2011) Polymorphisms in fatty acid binding protein 5 show association with type 2 diabetes. Diabetes Res Clin Pract 92: 82-91.
30. Oka K, Ishimura-Oka K, Chu MJ, Sullivan M, Krushkal J, et al. (1994) Mouse very-low-density-lipoprotein receptor (VLDLR) cDNA cloning, tissue-specific expression and evolutionary relationship with the low-density-lipoprotein receptor. Eur J Biochem 224: 975-982. (Pubitemid 24288861)
31. Jo H, Choe SS, Shin KC, Jang H, Lee JH, et al. (2013) ER stress induces hepatic steatosis via increased expression of the hepatic VLDL receptor. Hepatology 57: 1366-1377.
32. Wu KC, Cui JY, Klaassen CD (2012) Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver. PLoS One 7: e39006.
33. Klaassen CD, Reisman SA (2010) Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver. Toxicol Appl Pharmacol 244: 57-65.
34. Desmots F, Rissel M, Pigeon C, Loyer P, Loreal O, et al. (2002) Differential effects of iron overload on GST isoform expression in mouse liver and kidney and correlation between GSTA4 induction and overproduction of free radicles. Free Radic Biol Med 32: 93-101. (Pubitemid 34045141)
35. Larson-Meyer DE, Newcomer BR, Heilbronn LK, Volaufova J, Smith SR, et al. (2008) Effect of 6-month calorie restriction and exercise on serum and liver lipids and markers of liver function. Obesity (Silver Spring) 16: 1355-1362. (Pubitemid 351770499)
36. Beher WT, Baker GD, Penney DG (1963) A comparative study of the effects of bile acids and cholesterol on cholesterol metabolism in the mouse, rat, hamster and guinea pig. J Nutr 79: 523-530.
37. Nishina PM, Verstuyft J, Paigen B (1990) Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J Lipid Res 31: 859-869. (Pubitemid 20175012)
38. Murphy C, Parini P, Wang J, Bjorkhem I, Eggertsen G, et al. (2005) Cholic acid as key regulator of cholesterol synthesis, intestinal absorption and hepatic storage in mice. Biochim Biophys Acta 1735: 167-175. (Pubitemid 41140426)
39. Li T, Francl JM, Boehme S, Ochoa A, Zhang Y, et al. (2012) Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity. J Biol Chem 287: 1861-1873.
40. Arteel GE (2012) Beyond reasonable doubt: Who is the culprit in lipotoxicity in NAFLD/NASH? Hepatology 55: 2030-2032.
41. Enjoji M, Nakamuta M (2010) Is the control of dietary cholesterol intake sufficiently effective to ameliorate nonalcoholic fatty liver disease? World J Gastroenterol 16: 800-803.
42. Subramanian S, Goodspeed L, Wang S, Kim J, Zeng L, et al. (2011) Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. J Lipid Res 52: 1626-1635.
43. Zadravec D, Brolinson A, Fisher RM, Carneheim C, Csikasz RI, et al. (2010) Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity. FASEB J 24: 4366-4377.
44. Thornton SJ, Wong E, Lee SD, Wasan KM (2008) Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism. Lipids Health Dis 7: 21.
45. Tang W, Jia L, Ma Y, Xie P, Haywood J, et al. (2011) Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liver. Biochim Biophys Acta 1811: 549-555.
46. Hoekstra M, Stitzinger M, van Wanrooij EJ, Michon IN, Kruijt JK, et al. (2006) Microarray analysis indicates an important role for FABP5 and putative novel FABPs on a Western-type diet. J Lipid Res 47: 2198-2207. (Pubitemid 44936130)
47. Reilich P, Horvath R, Krause S, Schramm N, Turnbull DM, et al. (2011) The phenotypic spectrum of neutral lipid storage myopathy due to mutations in the PNPLA2 gene. J Neurol 258: 1987-1997.
48. Haynes P, Liangpunsakul S, Chalasani N (2004) Nonalcoholic fatty liver disease in individuals with severe obesity. Clin Liver Dis 8: 535-547, viii. (Pubitemid 39141141)
49. Rolo AP, Teodoro JS, Palmeira CM (2012) Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis. Free Radic Biol Med 52: 59-69.
50. Wu G, Fang YZ, Yang S, Lupton JR, Turner ND (2004) Glutathione metabolism and its implications for health. J Nutr 134: 489-492. (Pubitemid 38298485)
51. Leonard MO, Kieran NE, Howell K, Burne MJ, Varadarajan R, et al. (2006) Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury. FASEB J 20: 2624-2626.
52. Sohal RS, Orr WC (2012) The redox stress hypothesis of aging. Free Radic Biol Med 52: 539-555.
53. Walsh ME, Shi Y, Van Remmen H (2013) The effects of dietary restriction on oxidative stress in rodents. Free Radic Biol Med.
54. Desai MS, Mariscalco MM, Tawil A, Vallejo JG, Smith CW (2008) Atherogenic diet-induced hepatitis is partially dependent on murine TLR4. J Leukoc Biol 83: 1336-1344. (Pubitemid 351960312)
55. Vergnes L, Phan J, Strauss M, Tafuri S, Reue K (2003) Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression. J Biol Chem 278: 42774-42784. (Pubitemid 37345887)
56. Wang Q, Perrard XD, Perrard JL, Mansoori A, Raya JL, et al. (2011) Differential effect of weight loss with low-fat diet or high-fat diet restriction on inflammation in the liver and adipose tissue of mice with diet-induced obesity. Atherosclerosis 219: 100-108.
57. Friend PS, Fernandes G, Good RA, Michael AF, Yunis EJ (1978) Dietary restrictions early and late: effects on the nephropathy of the NZB X NZW mouse. Lab Invest 38: 629-632. (Pubitemid 8372919)
58. Sun D, Krishnan A, Su J, Lawrence R, Zaman K, et al. (2004) Regulation of immune function by calorie restriction and cyclophosphamide treatment in lupus-prone NZB/NZW F1 mice. Cell Immunol 228: 54-65. (Pubitemid 38760123)
59. O'Brien RM, Granner DK (1991) Regulation of gene expression by insulin. Biochem J 278 (Pt 3): 609-619.
60. Towle HC, Kaytor EN, Shih HM (1997) Regulation of the expression of lipogenic enzyme genes by carbohydrate. Annu Rev Nutr 17: 405-433. (Pubitemid 27328807)