Bardoxolone methyl (BARD) ameliorates aristolochic acid (AA)-induced acute kidney injury through Nrf2 pathway

Toxicology

Volumn 318, Issue 1, 2014, Pages 22-31

  Wu, Juan ^a,b   Liu, Xinhui ^a,b   Fan, Jinjin ^a,b   Chen, Wenfang ^a   Wang, Juan ^a,b   Zeng, Youjia ^a,b   Feng, Xiaorang ^a,b   Yu, Xueqing ^a,b   Yang, Xiao ^a,b  

^a SUN YAT SEN UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

Acute kidney injury; Aristolochic acid; Bardoxolone methyl; Heme oxygenase 1; NAD(P)H quinone oxidoreductase 1; Nuclear factor erythroid 2 related factor 2

Indexed keywords

ARISTOLOCHIC ACID; BARDOXOLONE METHYL; CREATININE; HEME OXYGENASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYTOPLASM; DOWN REGULATION; DRUG STRUCTURE; GENE EXPRESSION; GLOMERULUS; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; KIDNEY CORTEX; KIDNEY DYSFUNCTION; KIDNEY PARENCHYMA; KIDNEY TUBULE; KIDNEY TUBULE DAMAGE; KIDNEY TUBULE NECROSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RENAL PROTECTION; SIGNAL TRANSDUCTION; UPREGULATION; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING;

ACUTE KIDNEY INJURY; ARISTOLOCHIC ACID; BARDOXOLONE METHYL; HEME OXYGENASE-1; NAD(P)H QUINONE OXIDOREDUCTASE-1; NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2;

ACUTE KIDNEY INJURY; ANIMALS; ARISTOLOCHIC ACIDS; CRYOPROTECTIVE AGENTS; DISEASE MODELS, ANIMAL; HEME OXYGENASE-1; KIDNEY; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; OLEANOLIC ACID;

EID: 84895739540     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.01.008     Document Type: Article

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