TNF-α induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways

Acta Pharmacologica Sinica

Volumn 35, Issue 3, 2014, Pages 339-350

  Lo, Huey Ming ^a,b   Lai, Tsung Hsuan ^a,c,d   Li, Chih Hung ^a   Wu, Wen Bin ^a  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^c CATHAY GENERAL HOSPITAL   (Taiwan)

^d NATIONAL CENTRAL UNIVERSITY   (Taiwan)

Author keywords

chemokine; CXCL1; dexamethasone; GRO ; JNK; monocyte; p38 MAPK; PI3K; TNF; vascular endothelial cell

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CXCL1 CHEMOKINE; DEXAMETHASONE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; THROMBIN; TUMOR NECROSIS FACTOR ALPHA; CXCL1 PROTEIN, HUMAN; MESSENGER RNA; PROTEIN KINASE INHIBITOR;

ARTICLE; CELL GROWTH ASSAY; CELL MIGRATION; CELL SIGNALING ASSAY; CELL VIABILITY ASSAY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; MONOCYTE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; COCULTURE; DOSE RESPONSE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS; SIGNAL TRANSDUCTION; TIME; UPREGULATION;

CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINE CXCL1; CHEMOTAXIS, LEUKOCYTE; COCULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASE; PROTEIN KINASE INHIBITORS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84895535173     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.182     Document Type: Article

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