Multiple levels of chemokine receptor regulation in the control of mouse natural killer cell development

Frontiers in Immunology

Volumn 5, Issue FEB, 2014, Pages

  Bernardini, Giovanni ^a   Benigni, Giorgia ^a   Antonangeli, Fabrizio ^a   Ponzetta, Andrea ^a   Santoni, Angela ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

Author keywords

Bone marrow; Chemokine receptor; Lymphocyte development and function; MicroRNA; NK cell; Transcription factors

Indexed keywords

ALPHA1 INTEGRIN; ALPHA2 INTEGRIN; CD11B ANTIGEN; CD16 ANTIGEN; CD69 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CCR9; CHEMOKINE RECEPTOR CX3CR1; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR6; CXCL16 CHEMOKINE; EOMESODERMIN; GAMMA INTERFERON; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 7 RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MICRORNA; MICRORNA 150; MICRORNA 155; MICRORNA 181; SECONDARY LYMPHOID TISSUE CHEMOKINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; TRANSCRIPTION FACTOR GATA 3; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

APOPTOSIS; BONE MARROW; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CYTOTOXICITY; GENE EXPRESSION; HOMEOSTASIS; HUMAN; MICROENVIRONMENT; NATURAL KILLER CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHORT SURVEY; SIGNAL TRANSDUCTION;

EID: 84895524609     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00044     Document Type: Short Survey

References (57)

1. Lanier LL. Up on the tightrope: natural killer cell activation and inhibition. Nat Immunol (2008) 9:495-502. doi: 10.1038/ni1581.
2. Dorfman JR, Raulet DH. Acquisition of Ly49 receptor expression by developing natural killer cells. J Exp Med (1998) 187:609-18. doi:10.1084/jem.187.4.609.
3. Rosmaraki EE, Douagi I, Roth C, Colucci F, Cumano A, Di Santo JP. Identification of committed NK cell progenitors in adult murine bone marrow. Eur J Immunol (2001) 31:1900-9. doi:10.1002/1521-4141(200106)31:6<::AID-IMMU1900>3.0.CO;2-M.
4. Di Santo JP. Natural killer cell developmental pathways: a question of balance. Annu Rev Immunol (2006) 24:257-86. doi:10.1146/annurev.immunol.24.021605.090700.
5. Carotta S, Pang SH, Nutt SL, Belz GT. Identification of the earliest NK-cell precursor in the mouse BM. Blood (2011) 117:5449-52. doi:10.1182/blood-2010-11-318956.
6. Fathman JW, Bhattacharya D, Inlay MA, Seita J, Karsunky H, Weissman IL. Identification of the earliest natural killer cell-committed progenitor in murine bone marrow. Blood (2011) 118:5439-47. doi:10.1182/blood-2011-04-348912.
7. Chiossone L, Chaix J, Fuseri N, Roth C, Vivier E, Walzer T. Maturation of mouse NK cells is a 4-stage developmental program. Blood (2009) 113:5488-96. doi:10.1182/blood-2008-10-187179.
8. Huntington ND, Tabarias H, Fairfax K, Brady J, Hayakawa Y, Degli-Esposti MA, et al. NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation. J Immunol (2007) 178:4764-70.
9. Sciume G, De Angelis G, Benigni G, Ponzetta A, Morrone S, Santoni A, et al. CX3CR1 expression defines 2 KLRG1+ mouse NK-cell subsets with distinct functional properties and positioning in the bone marrow. Blood (2011) 117:4467-75. doi:10.1182/blood-2010-07-297101.
10. Takeda K, Cretney E, Hayakawa Y, Ota T, Akiba H, Ogasawara K, et al. TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood (2005) 105:2082-9. doi:10.1182/blood-2004-08-3262.
11. Wu X, Chen Y, Wei H, Sun R, Tian Z. Development of murine hepatic NK cells during ontogeny: comparison with spleen NK cells. Clin Dev Immunol (2012) 2012:759765. doi:10.1155/2012/759765.
12. Peng H, Jiang X, Chen Y, Sojka DK, Wei H, Gao X, et al. Liver-resident NK cells confer adaptive immunity in skin-contact inflammation. J Clin Invest (2013) 123:1444-56. doi:10.1172/JCI66381.
13. Gordon SM, Chaix J, Rupp LJ, Wu J, Madera S, Sun JC, et al. The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity (2012) 36:55-67. doi:10.1016/j.immuni.2011.11.016.
14. Vosshenrich CA, Garcia-Ojeda ME, Samson-Villeger SI, Pasqualetto V, Enault L, Richard-Le Goff O, et al. A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127. Nat Immunol (2006) 7:1217-24. doi:10.1038/ni1395.
15. Stewart CA, Walzer T, Robbins SH, Malissen B, Vivier E, Prinz I. Germ-line and rearranged Tcrd transcription distinguish bona fide NK cells and NK-like gammadelta T cells. Eur J Immunol (2007) 37:1442-52. doi:10.1002/eji.200737354.
16. Luevano M, Madrigal A, Saudemont A. Transcription factors involved in the regulation of natural killer cell development and function: an update. Front Immunol (2012) 3:319. doi:10.3389/fimmu.2012.00319.
17. Huntington ND, Nutt SL, Carotta S. Regulation of murine natural killer cell commitment. Front Immunol (2013) 4:14. doi:10.3389/fimmu.2013.00014.
18. Bezman NA, Cedars E, Steiner DF, Blelloch R, Hesslein DG, Lanier LL. Distinct requirements of microRNAs in NK cell activation, survival, and function. J Immunol (2010) 185:3835-46. doi:10.4049/jimmunol.1000980.
19. Gascoyne DM, Long E, Veiga-Fernandes H, De Boer J, Williams O, Seddon B, et al. The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol (2009) 10:1118-24. doi:10.1038/ni.1787.
20. Boos MD, Yokota Y, Eberl G, Kee BL. Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity. J Exp Med (2007) 204:1119-30. doi:10.1084/jem.20061959.
21. Kim S, Iizuka K, Kang HS, Dokun A, French AR, Greco S, et al. In vivo developmental stages in murine natural killer cell maturation. Nat Immunol (2002) 3:523-8. doi:10.1038/ni796.
22. Jiang X, Chen Y, Peng H, Tian Z. Single line or parallel lines: NK cell differentiation driven by T-bet and Eomes. Cell Mol Immunol (2012) 9:193-4. doi:10.1038/cmi.2012.8.
23. Bezman NA, Chakraborty T, Bender T, Lanier LL. miR-150 regulates the development of NK and iNKT cells. J Exp Med (2011) 208:2717-31. doi:10.1084/jem.20111386.
24. Trotta R, Chen L, Ciarlariello D, Josyula S, Mao C, Costinean S, et al. miR-155 regulates IFN-gamma production in natural killer cells. Blood (2012) 119:3478-85. doi:10.1182/blood-2011-12-398099.
25. Zawislak CL, Beaulieu AM, Loeb GB, Karo J, Canner D, Bezman NA, et al. Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155. Proc Natl Acad Sci U S A (2013) 110:6967-72. doi:10.1073/pnas.1304410110.
26. Cichocki F, Felices M, McCullar V, Presnell SR, Al-Attar A, Lutz CT, et al. Cutting edge: microRNA-181 promotes human NK cell development by regulating Notch signaling. J Immunol (2011) 187:6171-5. doi:10.4049/jimmunol.1100835.
27. Bonecchi R, Galliera E, Borroni EM, Corsi MM, Locati M, Mantovani A. Chemokines and chemokine receptors: an overview. Front Biosci (Landmark Ed) (2009) 14:540-51. doi:10.2741/3261.
28. Cyster JG, Schwab SR. Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs. Annu Rev Immunol (2012) 30:69-94. doi:10.1146/annurev-immunol-020711-075011.
29. Ma Q, Jones D, Borghesani PR, Segal RA, Nagasawa T, Kishimoto T, et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4-and SDF-1-deficient mice. Proc Natl Acad Sci U S A (1998) 95:9448-53. doi:10.1073/pnas.95.16.9448.
30. Zou YR, Kottmann AH, Kuroda M, Taniuchi I, Littman DR. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature (1998) 393:595-9. doi:10.1038/31269.
31. Egawa T, Kawabata K, Kawamoto H, Amada K, Okamoto R, Fujii N, et al. The earliest stages of B cell development require a chemokine stromal cell-derived factor/pre-B cell growth-stimulating factor. Immunity (2001) 15:323-34. doi:10.1016/S1074-7613(01)00185-6.
32. Tokoyoda K, Egawa T, Sugiyama T, Choi BI, Nagasawa T. Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity (2004) 20:707-18. doi:10.1016/j.immuni.2004.05.001.
33. Nagasawa T. Microenvironmental niches in the bone marrow required for B-cell development. Nat Rev Immunol (2006) 6:107-16. doi:10.1038/nri1780.
34. Glodek AM, Honczarenko M, Le Y, Campbell JJ, Silberstein LE. Sustained activation of cell adhesion is a differentially regulated process in B lymphopoiesis. J Exp Med (2003) 197:461-73. doi:10.1084/jem.20021477.
35. Glodek AM, Le Y, Dykxhoorn DM, Park SY, Mostoslavsky G, Mulligan R, et al. Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells. Leukemia (2007) 21:1723-32. doi:10.1038/sj.leu.2404769.
36. Palmesino E, Moepps B, Gierschik P, Thelen M. Differences in CXCR4-mediated signaling in B cells. Immunobiology (2006) 211:377-89. doi:10.1016/j.imbio.2005.12.003.
37. Bunting MD, Comerford I, McColl SR. Finding their niche: chemokines directing cell migration in the thymus. Immunol Cell Biol (2011) 89:185-96. doi:10.1038/icb.2010.142.
38. Trampont PC, Tosello-Trampont AC, Shen Y, Duley AK, Sutherland AE, Bender TP, et al. CXCR4 acts as a costimulator during thymic beta-selection. Nat Immunol (2010) 11:162-70. doi:10.1038/ni.1830.
39. Janas ML, Varano G, Gudmundsson K, Noda M, Nagasawa T, Turner M. Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4. J Exp Med (2010) 207:247-61. doi:10.1084/jem.20091430.
40. Bunting MD, Comerford I, Seach N, Hammett MV, Asquith DL, Korner H, et al. CCX-CKR deficiency alters thymic stroma impairing thymocyte development and promoting autoimmunity. Blood (2013) 121:118-28. doi:10.1182/blood-2012-06-434886.
41. Germanov E, Veinotte L, Cullen R, Chamberlain E, Butcher EC, Johnston B. Critical role for the chemokine receptor CXCR6 in homeostasis and activation of CD1d-restricted NKT cells. J Immunol (2008) 181:81-91. doi:10.4049/jimmunol.0803520.
42. Bernardini G, Gismondi A, Santoni A. Chemokines and NK cells: regulators of development, trafficking and functions. Immunol Lett (2012) 145:39-46. doi:10.1016/j.imlet.2012.04.014.
43. Walzer T, Chiossone L, Chaix J, Calver A, Carozzo C, Garrigue-Antar L, et al. Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor. Nat Immunol (2007) 8:1337-44. doi:10.1038/ni1523.
44. Bernardini G, Sciume G, Bosisio D, Morrone S, Sozzani S, Santoni A. CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets. Blood (2008) 111:3626-34. doi:10.1182/blood-2007-08-106203.
45. Noda M, Omatsu Y, Sugiyama T, Oishi S, Fujii N, Nagasawa T. CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice. Blood (2011) 117:451-8. doi:10.1182/blood-2010-04-277897.
46. Mayol K, Biajoux V, Marvel J, Balabanian K, Walzer T. Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking. Blood (2011) 118:4863-71. doi:10.1182/blood-2011-06-362574.
47. Weiss ID, Shoham H, Wald O, Wald H, Beider K, Abraham M, et al. Ccr5 deficiency regulates the proliferation and trafficking of natural killer cells under physiological conditions. Cytokine (2011) 54:249-57. doi:10.1016/j.cyto.2011.01.011.
48. Ponzetta A, Sciume G, Benigni G, Antonangeli F, Morrone S, Santoni A, et al. CX3CR1 regulates the maintenance of KLRG1+ NK cells into the bone marrow by promoting their entry into circulation. J Immunol (2013) 191:5684-94. doi:10.4049/jimmunol.1300090.
49. Paust S, Gill HS, Wang BZ, Flynn MP, Moseman EA, Senman B, et al. Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses. Nat Immunol (2010) 11:1127-35. doi:10.1038/ni.1953.
50. Lisignoli G, Toneguzzi S, Pozzi C, Piacentini A, Grassi F, Ferruzzi A, et al. Chemokine expression by subchondral bone marrow stromal cells isolated from osteoarthritis (OA) and rheumatoid arthritis (RA) patients. Clin Exp Immunol (1999) 116:371-8. doi:10.1046/j.1365-2249.1999.00893.x.
51. Hoshino A, Iimura T, Ueha S, Hanada S, Maruoka Y, Mayahara M, et al. Deficiency of chemokine receptor CCR1 causes osteopenia due to impaired functions of osteoclasts and osteoblasts. J Biol Chem (2010) 285:28826-37. doi:10.1074/jbc.M109.099424.
52. Wald O, Weiss ID, Wald H, Shoham H, Bar-Shavit Y, Beider K, et al. IFN-gamma acts on T cells to induce NK cell mobilization and accumulation in target organs. J Immunol (2006) 176:4716-29.
53. Tano N, Kim HW, Ashraf M. microRNA-150 regulates mobilization and migration of bone marrow-derived mononuclear cells by targeting Cxcr4. PLoS One (2011) 6:e23114. doi:10.1371/journal.pone.0023114.
54. Henao-Mejia J, Williams A, Goff LA, Staron M, Licona-Limon P, Kaech SM, et al. The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis. Immunity (2013) 38:984-97. doi:10.1016/j.immuni.2013.02.021.
55. Jenne CN, Enders A, Rivera R, Watson SR, Bankovich AJ, Pereira JP, et al. T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. J Exp Med (2009) 206:2469-81. doi:10.1084/jem.20090525.
56. Kee BL. E and ID proteins branch out. Nat Rev Immunol (2009) 9:175-84. doi:10.1038/nri2507.
57. Jones-Mason ME, Zhao X, Kappes D, Lasorella A, Iavarone A, Zhuang Y. E protein transcription factors are required for the development of CD4(+) lineage T cells. Immunity (2012) 36:348-61. doi:10.1016/j.immuni.2012.02.010.