Computational and experimental analysis of drug binding to the Influenza M2 channel

Biochimica et Biophysica Acta - Biomembranes

Volumn 1838, Issue 4, 2014, Pages 1068-1073

  Alhadeff, Raphael ^a   Assa, Dror ^a   Astrahan, Peleg ^a   Krugliak, Miriam ^a   Arkin, Isaiah T ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Anti flu agent; Cell based assay; Channel blocker; Potential of mean force

Indexed keywords

ANTIVIRUS AGENT; N [[[1 (1 ADAMANTYL)ETHYL]AMINO]CARBONOTHIOYL] 3 (2 THIENYL); N [[[1 (1 ADAMANTYL)ETHYL]AMINO]CARBONOTHIOYL] NICOTINAMIDE; PROTEIN M2; PYRIDINE DERIVATIVE; RIMANTADINE; UNCLASSIFIED DRUG;

ANTIVIRAL RESISTANCE; ARTICLE; BINDING ASSAY; CELL ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CONCENTRATION; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; EXPERIMENTAL STUDY; INFLUENZA A; MEDIAN EFFECTIVE CONCENTRATION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL;

ANTI-FLU AGENT; CELL BASED ASSAY; CHANNEL BLOCKER; POTENTIAL OF MEAN FORCE;

ANTIVIRAL AGENTS; DRUG RESISTANCE, VIRAL; MOLECULAR DYNAMICS SIMULATION; VIRAL MATRIX PROTEINS;

EID: 84895523813     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2013.07.033     Document Type: Article

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