Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia

Neuroscience

Volumn 265, Issue , 2014, Pages 147-157

  Singh, V ^a,e   Bhatia, H S ^a   Kumar, A ^a,b   de Oliveira, A C P ^a,c   Fiebich, B L ^a,d  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^d VIVACELL BIOTECHNOLOGY GMBH   (Germany)

^e LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Cyclooxygenase 2; Histone deacetylase inhibitors; Microglia; Microsomal prostaglandin E synthase 1; Prostaglandin

Indexed keywords

8 ISOPROSTAGLANDIN F2 ALPHA; BUTYRIC ACID; CYCLOOXYGENASE 2; HISTONE DEACETYLASE; HISTONE H3; HISTONE H3 K18; I KAPPA B ALPHA; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROSTAGLANDIN; PROSTAGLANDIN D2; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; COX 2 GENE; CYTOKINE RELEASE; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME MODIFICATION; GENE; GENE EXPRESSION REGULATION; HISTONE ACETYLATION; IMMUNOREACTIVITY; IN VITRO STUDY; MICROGLIA; MOUSE; MPGES 1 GENE; NERVE REGENERATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; TRANSCRIPTION REGULATION; UPREGULATION;

EID: 84895451543     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.01.037     Document Type: Article

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