Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase C

British Journal of Pharmacology

Volumn 171, Issue 5, 2014, Pages 1330-1340

  Illing, Susann ^a   Mann, Anika ^a   Schulz, Stefan ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

analgesia; MOR; morphine; opioid receptor; phosphorylation; PKC; tolerance

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 3 [8 [(DIMETHYLAMINO)METHYL] 6,7,8,9 TETRAHYDROPYRIDO[1,2 A]INDOL 10 YL] 4 (1 METHYL 1H INDOL 3 YL) 1H PYRROLE 2,5 DIONE; BISINDOLYLMALEIMIDE; MU OPIATE RECEPTOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHORBOL ESTER; POLYCLONAL ANTIBODY; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C INHIBITOR; RUBOXISTAURIN; SMALL INTERFERING RNA; SUBSTANCE P RECEPTOR;

ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; GENE SILENCING; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

ANALGESIA; MOR; MORPHINE; OPIOID RECEPTOR; PHOSPHORYLATION; PKC; TOLERANCE;

ANALGESICS, OPIOID; ANIMALS; BRAIN; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN KINASE C; RECEPTORS, OPIOID, MU; TETRADECANOYLPHORBOL ACETATE;

EID: 84895151259     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12546     Document Type: Article

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