The HIF-1 transcription complex is essential for translational control of myeloid hematopoietic cell function by maintaining mTOR phosphorylation

Cellular and Molecular Life Sciences

Volumn 71, Issue 4, 2014, Pages 699-710

  Yasinska, Inna M ^a   Gibbs, Bernhard F ^a   Lall, Gurprit S ^a   Sumbayev, Vadim V ^a  

^a MEDWAY SCHOOL OF PHARMACY   (United Kingdom)

Author keywords

HIF 1 transcription complex; Inflammation; mTOR (mammalian target of rapamycin); Myeloid cells

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR 1; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE; TLR2 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 2;

ANIMAL; BLOOD CELL; BONE MARROW CELL; CELL LINE; ENZYME ACTIVATION; GENETICS; HUMAN; MALE; METABOLISM; MOUSE; PHOSPHORYLATION; RNA INTERFERENCE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BLOOD CELLS; CELL LINE; ENZYME ACTIVATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; MALE; MICE; MYELOID CELLS; PHOSPHORYLATION; RNA INTERFERENCE; RNA, SMALL INTERFERING; TOLL-LIKE RECEPTOR 2; TOR SERINE-THREONINE KINASES;

EID: 84895144471     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1421-2     Document Type: Review

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