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Volumn 16, Issue 3, 2014, Pages 298-308

Optimization of the therapeutic efficacy of human umbilical cord blood-mesenchymal stromal cells in an NSG mouse xenograft model of graft-versus-host disease

Author keywords

Graft versus host disease; Human umbilical cord blood mesenchymal stromal cells; NSG mice; Therapeutic effect

Indexed keywords

GRAFT-VERSUS-HOST DISEASE; HUMAN UMBILICAL CORD BLOOD-MESENCHYMAL STROMAL CELLS; NSG MICE; THERAPEUTIC EFFECT;

EID: 84895090610     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2013.10.012     Document Type: Article
Times cited : (30)

References (40)
  • 1
    • 0033152326 scopus 로고    scopus 로고
    • Factors associated with outcome after cord blood transplantation in children with acute leukemia: Eurocord-Cord Blood Transplant Group
    • Locatelli F., Rocha V., Chastang C., Arcese W., Michel G., Abecasis M., et al. Factors associated with outcome after cord blood transplantation in children with acute leukemia: Eurocord-Cord Blood Transplant Group. Blood 1999, 93:3662-3671.
    • (1999) Blood , vol.93 , pp. 3662-3671
    • Locatelli, F.1    Rocha, V.2    Chastang, C.3    Arcese, W.4    Michel, G.5    Abecasis, M.6
  • 2
    • 33947546893 scopus 로고    scopus 로고
    • Management of acute graft-versus-host disease
    • Bacigalupo A. Management of acute graft-versus-host disease. Br J Hematol 2007, 137:87-98.
    • (2007) Br J Hematol , vol.137 , pp. 87-98
    • Bacigalupo, A.1
  • 3
    • 0030861750 scopus 로고    scopus 로고
    • Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines
    • Hill G.R., Crawford J.M., Cooke K.R., Brinson Y.S., Pan L., Ferrara J.L. Total body irradiation and acute graft-versus-host disease: the role of gastrointestinal damage and inflammatory cytokines. Blood 1997, 90:3204-3213.
    • (1997) Blood , vol.90 , pp. 3204-3213
    • Hill, G.R.1    Crawford, J.M.2    Cooke, K.R.3    Brinson, Y.S.4    Pan, L.5    Ferrara, J.L.6
  • 4
    • 0035100518 scopus 로고    scopus 로고
    • Acute graft-versus-host disease: pathobiology and management
    • Goker H., Haznedaroglu I.C., Chao N.J. Acute graft-versus-host disease: pathobiology and management. Exp Hematol 2001, 29:259-277.
    • (2001) Exp Hematol , vol.29 , pp. 259-277
    • Goker, H.1    Haznedaroglu, I.C.2    Chao, N.J.3
  • 5
    • 27444434871 scopus 로고    scopus 로고
    • Recent advances in the treatment of graft-versus-host disease
    • Iwasaki T. Recent advances in the treatment of graft-versus-host disease. Clin Med Res 2004, 2:243-252.
    • (2004) Clin Med Res , vol.2 , pp. 243-252
    • Iwasaki, T.1
  • 6
    • 44249120602 scopus 로고    scopus 로고
    • Current and novel therapies in acute GVHD
    • Ho V.T., Cutler C. Current and novel therapies in acute GVHD. Best Pract Res Clin Haematol 2008, 21:223-237.
    • (2008) Best Pract Res Clin Haematol , vol.21 , pp. 223-237
    • Ho, V.T.1    Cutler, C.2
  • 7
    • 0036048349 scopus 로고    scopus 로고
    • Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems
    • MacMillan M.L., Weisdorf D.J., Wagner J.E., DeFor T.E., Burns L.J., Ramsay N.K., et al. Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems. Biol Blood Marrow Transplant 2002, 8:387-394.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 387-394
    • MacMillan, M.L.1    Weisdorf, D.J.2    Wagner, J.E.3    DeFor, T.E.4    Burns, L.J.5    Ramsay, N.K.6
  • 8
    • 17844362706 scopus 로고    scopus 로고
    • Treatment of steroid-resistant acute graft-versus-host disease with anti-thymocyte globulin
    • Khoury H., Kashyap A., Adkins D.R., Brown R.A., Miller G., Vij R., et al. Treatment of steroid-resistant acute graft-versus-host disease with anti-thymocyte globulin. Bone Marrow Transplant 2001, 27:1059-1064.
    • (2001) Bone Marrow Transplant , vol.27 , pp. 1059-1064
    • Khoury, H.1    Kashyap, A.2    Adkins, D.R.3    Brown, R.A.4    Miller, G.5    Vij, R.6
  • 9
    • 17444379357 scopus 로고    scopus 로고
    • Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation
    • Le Blanc K., Ringdén O. Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2005, 11:321-334.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 321-334
    • Le Blanc, K.1    Ringdén, O.2
  • 10
    • 79951699743 scopus 로고    scopus 로고
    • Treatment of graft-versus-host-disease with mesenchymal stromal cells
    • Kebriaei P., Robinson S. Treatment of graft-versus-host-disease with mesenchymal stromal cells. Cytotherapy 2011, 13:262-268.
    • (2011) Cytotherapy , vol.13 , pp. 262-268
    • Kebriaei, P.1    Robinson, S.2
  • 11
    • 79952639223 scopus 로고    scopus 로고
    • Mesenchymal stromal cells for graft-versus-host disease
    • Tolar J., Villeneuve P., Keating A. Mesenchymal stromal cells for graft-versus-host disease. Hum Gene Ther 2011, 22:257-262.
    • (2011) Hum Gene Ther , vol.22 , pp. 257-262
    • Tolar, J.1    Villeneuve, P.2    Keating, A.3
  • 12
    • 84855552728 scopus 로고    scopus 로고
    • Multipotent mesenchymal stromal cells for the prophylaxis of acute graft-versus-host disease: a phase II study
    • Kuzmina L.A., Petinati N.A., Parovichnikova E.N., Lubimova L.S., Gribanova E.O., Gaponova T.V., et al. Multipotent mesenchymal stromal cells for the prophylaxis of acute graft-versus-host disease: a phase II study. Stem Cells Int 2012, 2012:968213. http://dx.doi.org/10.1155/2012/968213.
    • (2012) Stem Cells Int , vol.2012 , pp. 968213
    • Kuzmina, L.A.1    Petinati, N.A.2    Parovichnikova, E.N.3    Lubimova, L.S.4    Gribanova, E.O.5    Gaponova, T.V.6
  • 13
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific Tcells to their cognate peptide
    • Krampera M., Glennie S., Dyson J., Scott D., Laylor R., Simpson E., et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific Tcells to their cognate peptide. Blood 2003, 101:3722-3729.
    • (2003) Blood , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3    Scott, D.4    Laylor, R.5    Simpson, E.6
  • 14
    • 1842483153 scopus 로고    scopus 로고
    • Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation
    • Maitra B., Szekely E., Gjini K., Laughlin M.J., Dennis J., Haynesworth S.E., et al. Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation. Bone Marrow Transplant 2004, 33:597-604.
    • (2004) Bone Marrow Transplant , vol.33 , pp. 597-604
    • Maitra, B.1    Szekely, E.2    Gjini, K.3    Laughlin, M.J.4    Dennis, J.5    Haynesworth, S.E.6
  • 15
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S., Pittenger M.F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005, 105:1815-1822.
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 16
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M., Carlo-Stella C., Magni M., Milanesi M., Longoni P.D., Matteucci P., et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002, 99:3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6
  • 17
    • 34548118697 scopus 로고    scopus 로고
    • Mesenchymal stem cells of cord blood origin are effective at preventing but not treating graft-versus-host disease
    • Tisato V., Naresh K., Girdlestone J., Navarrete C., Dazzi F. Mesenchymal stem cells of cord blood origin are effective at preventing but not treating graft-versus-host disease. Leukemia 2007, 21:1992-1999.
    • (2007) Leukemia , vol.21 , pp. 1992-1999
    • Tisato, V.1    Naresh, K.2    Girdlestone, J.3    Navarrete, C.4    Dazzi, F.5
  • 18
    • 49649106257 scopus 로고    scopus 로고
    • IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
    • Polchert D., Sobinsky J., Douglas G., Kidd M., Moadsiri A., Reina E., et al. IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease. Eur J Immunol 2008, 38:1745-1755.
    • (2008) Eur J Immunol , vol.38 , pp. 1745-1755
    • Polchert, D.1    Sobinsky, J.2    Douglas, G.3    Kidd, M.4    Moadsiri, A.5    Reina, E.6
  • 19
    • 77950550604 scopus 로고    scopus 로고
    • Mesenchymal stromal cells inhibit graft-versus-host disease of mice in a dose-dependent manner
    • Joo S.Y., Cho K.A., Jung Y.J., Kim H.S., Park S.Y., Choi Y.B., et al. Mesenchymal stromal cells inhibit graft-versus-host disease of mice in a dose-dependent manner. Cytotherapy 2010, 12:361-370.
    • (2010) Cytotherapy , vol.12 , pp. 361-370
    • Joo, S.Y.1    Cho, K.A.2    Jung, Y.J.3    Kim, H.S.4    Park, S.Y.5    Choi, Y.B.6
  • 20
    • 70149119503 scopus 로고    scopus 로고
    • Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming
    • Highfill S.L., Kelly R.M., O'Shaughnessy M.J., Zhou Q., Xia L., Panoskaltsis-Mortari A., et al. Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming. Blood 2009, 114:693-701.
    • (2009) Blood , vol.114 , pp. 693-701
    • Highfill, S.L.1    Kelly, R.M.2    O'Shaughnessy, M.J.3    Zhou, Q.4    Xia, L.5    Panoskaltsis-Mortari, A.6
  • 21
    • 7244247149 scopus 로고    scopus 로고
    • Mesenchymal stem/progenitor cells developed in cultures from UC blood
    • Yang S.E., Ha C.W., Jung M., Jin H.J., Lee M., Song H., et al. Mesenchymal stem/progenitor cells developed in cultures from UC blood. Cytotherapy 2004, 6:476-486.
    • (2004) Cytotherapy , vol.6 , pp. 476-486
    • Yang, S.E.1    Ha, C.W.2    Jung, M.3    Jin, H.J.4    Lee, M.5    Song, H.6
  • 22
    • 0029909099 scopus 로고    scopus 로고
    • An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation, I: the roles of minor H antigens and endotoxin
    • Cooke K.R., Kobzik L., Martin T.R., Brewer J., Delmonte J., Crawford J.M., et al. An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation, I: the roles of minor H antigens and endotoxin. Blood 1996, 888:3230-3239.
    • (1996) Blood , vol.888 , pp. 3230-3239
    • Cooke, K.R.1    Kobzik, L.2    Martin, T.R.3    Brewer, J.4    Delmonte, J.5    Crawford, J.M.6
  • 23
    • 67649580473 scopus 로고    scopus 로고
    • Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice
    • Ito R., Katano I., Kawai K., Hirata H., Ogura T., Kamisako T., et al. Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice. Transplantation 2009, 87:1654-1658.
    • (2009) Transplantation , vol.87 , pp. 1654-1658
    • Ito, R.1    Katano, I.2    Kawai, K.3    Hirata, H.4    Ogura, T.5    Kamisako, T.6
  • 24
    • 34248213189 scopus 로고    scopus 로고
    • IL-10-transduced bone marrow mesenchymal stem cells can attenuate the severity of acute graft-versus-host disease after experimental allogeneic stem cell transplantation
    • Min C.K., Kim B.G., Park G., Cho B., Oh I.H. IL-10-transduced bone marrow mesenchymal stem cells can attenuate the severity of acute graft-versus-host disease after experimental allogeneic stem cell transplantation. Bone Marrow Transplant 2007, 39:637-645.
    • (2007) Bone Marrow Transplant , vol.39 , pp. 637-645
    • Min, C.K.1    Kim, B.G.2    Park, G.3    Cho, B.4    Oh, I.H.5
  • 25
    • 84862841834 scopus 로고    scopus 로고
    • Therapeutic efficacy of cord blood-derived mesenchymal stromal cells for the prevention of acute graft-versus-host disease in a xenogenic mouse model
    • Gregoire-Gauthier J., Selleri S., Fontaine F., Dieng M.M., Patey N., Despars G., et al. Therapeutic efficacy of cord blood-derived mesenchymal stromal cells for the prevention of acute graft-versus-host disease in a xenogenic mouse model. Stem Cells Dev 2012, 21:1616-1626.
    • (2012) Stem Cells Dev , vol.21 , pp. 1616-1626
    • Gregoire-Gauthier, J.1    Selleri, S.2    Fontaine, F.3    Dieng, M.M.4    Patey, N.5    Despars, G.6
  • 26
    • 0036142769 scopus 로고    scopus 로고
    • Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
    • Bartholomew A., Sturgeon C., Siatskas M., Ferrer K., McIntosh K., Patil S., et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol 2002, 30:42-48.
    • (2002) Exp Hematol , vol.30 , pp. 42-48
    • Bartholomew, A.1    Sturgeon, C.2    Siatskas, M.3    Ferrer, K.4    McIntosh, K.5    Patil, S.6
  • 27
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K., Rasmusson I., Sundberg B., Götherström C., Hassan M., Uzunel M., et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004, 363:1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3    Götherström, C.4    Hassan, M.5    Uzunel, M.6
  • 28
    • 84862777467 scopus 로고    scopus 로고
    • CXCR4-transduced mesenchymal stem cells protect mice against graft-versus-host disease
    • Chen W., Li M., Li Z., Yan Z., Cheng H., Pan B., et al. CXCR4-transduced mesenchymal stem cells protect mice against graft-versus-host disease. Immunol Lett 2012, 143:161-169.
    • (2012) Immunol Lett , vol.143 , pp. 161-169
    • Chen, W.1    Li, M.2    Li, Z.3    Yan, Z.4    Cheng, H.5    Pan, B.6
  • 29
    • 18444374992 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice
    • Noort W.A., Kruisselbrink A.B., in't Anker P.S., Kruger M., van Bezooijen R.L., de Paus R.A., et al. Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol 2002, 30:870-878.
    • (2002) Exp Hematol , vol.30 , pp. 870-878
    • Noort, W.A.1    Kruisselbrink, A.B.2    in't Anker, P.S.3    Kruger, M.4    van Bezooijen, R.L.5    de Paus, R.A.6
  • 30
    • 24744434734 scopus 로고    scopus 로고
    • Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction
    • Kraitchman D.L., Tatsumi M., Gilson W.D., Ishimori T., Kedziorek D., Walczak P., et al. Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation 2005, 112:1451-1461.
    • (2005) Circulation , vol.112 , pp. 1451-1461
    • Kraitchman, D.L.1    Tatsumi, M.2    Gilson, W.D.3    Ishimori, T.4    Kedziorek, D.5    Walczak, P.6
  • 31
    • 84863385503 scopus 로고    scopus 로고
    • Marrow stromal cell infusion rescues hematopoiesis in lethally irradiated mice despite rapid clearance after infusion
    • Yang X., Balakrishnan I., Torok-Storb B., Pillai M.M. Marrow stromal cell infusion rescues hematopoiesis in lethally irradiated mice despite rapid clearance after infusion. Adv Hematol 2012, 2012:142530. http://dx.doi.org/10.1155/2012/142530.
    • (2012) Adv Hematol , vol.2012 , pp. 142530
    • Yang, X.1    Balakrishnan, I.2    Torok-Storb, B.3    Pillai, M.M.4
  • 32
    • 84876086426 scopus 로고    scopus 로고
    • Human mesenchymal stem cells suppress donor CD4(+) T cell proliferation and reduce pathology in a humanized mouse model of acute graft-versus-host disease
    • Tobin L.M., Healy M.E., English K., Mahon B.P. Human mesenchymal stem cells suppress donor CD4(+) T cell proliferation and reduce pathology in a humanized mouse model of acute graft-versus-host disease. Clin Exp Immunol 2013, 172:333-348.
    • (2013) Clin Exp Immunol , vol.172 , pp. 333-348
    • Tobin, L.M.1    Healy, M.E.2    English, K.3    Mahon, B.P.4
  • 33
    • 84875426087 scopus 로고    scopus 로고
    • Impact of bone marrow-derived mesenchymal stromal cells on experimental xenogeneic graft-versus-host disease
    • Bruck F., Belle L., Lechanteur C., de Leval L., Hannon M., Dubois S., et al. Impact of bone marrow-derived mesenchymal stromal cells on experimental xenogeneic graft-versus-host disease. Cytotherapy 2013, 15:267-279.
    • (2013) Cytotherapy , vol.15 , pp. 267-279
    • Bruck, F.1    Belle, L.2    Lechanteur, C.3    de Leval, L.4    Hannon, M.5    Dubois, S.6
  • 34
    • 7244224904 scopus 로고    scopus 로고
    • Asmall proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow
    • Wynn R.F., Hart C.A., Corradi-Perini C., O'Neill L., Evans C.A., Wraith J.E., et al. Asmall proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow. Blood 2004, 104:2643-2645.
    • (2004) Blood , vol.104 , pp. 2643-2645
    • Wynn, R.F.1    Hart, C.A.2    Corradi-Perini, C.3    O'Neill, L.4    Evans, C.A.5    Wraith, J.E.6
  • 35
    • 34548768335 scopus 로고    scopus 로고
    • Differential regulation of hypoxia-induced CXCR4 triggering during B-cell development and lymphomagenesis
    • Piovan E., Tosello V., Indraccolo S., Masiero M., Persano L., Esposito G., et al. Differential regulation of hypoxia-induced CXCR4 triggering during B-cell development and lymphomagenesis. Cancer Res 2007, 67:8605-8614.
    • (2007) Cancer Res , vol.67 , pp. 8605-8614
    • Piovan, E.1    Tosello, V.2    Indraccolo, S.3    Masiero, M.4    Persano, L.5    Esposito, G.6
  • 37
    • 4043184065 scopus 로고    scopus 로고
    • Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
    • Ceradini D.J., Kulkarni A.R., Callaghan M.J., Tepper O.M., Bastidas N., Kleinman M.E., et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 2004, 10:858-864.
    • (2004) Nat Med , vol.10 , pp. 858-864
    • Ceradini, D.J.1    Kulkarni, A.R.2    Callaghan, M.J.3    Tepper, O.M.4    Bastidas, N.5    Kleinman, M.E.6
  • 38
    • 43049173715 scopus 로고    scopus 로고
    • Hypoxia enhances CXCR4 expression favoring microglia migration via HIF-1alpha activation
    • Wang X., Li C., Chen Y., Hao Y., Zhou W., Chen C., et al. Hypoxia enhances CXCR4 expression favoring microglia migration via HIF-1alpha activation. Biochem Biophys Res Commun 2008, 371:283-288.
    • (2008) Biochem Biophys Res Commun , vol.371 , pp. 283-288
    • Wang, X.1    Li, C.2    Chen, Y.3    Hao, Y.4    Zhou, W.5    Chen, C.6
  • 39
    • 34548739439 scopus 로고    scopus 로고
    • Short-term exposure of multipotent stromal cells to low oxygen increases their expression of CX3CR1 and CXCR4 and their engraftment in vivo
    • Hung S.C., Pochampally R.R., Hsu S.C., Sanchez C., Chen S.C., Spees J., et al. Short-term exposure of multipotent stromal cells to low oxygen increases their expression of CX3CR1 and CXCR4 and their engraftment in vivo. PLoS One 2007, 2:e416.
    • (2007) PLoS One , vol.2
    • Hung, S.C.1    Pochampally, R.R.2    Hsu, S.C.3    Sanchez, C.4    Chen, S.C.5    Spees, J.6
  • 40
    • 34548174756 scopus 로고    scopus 로고
    • Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis
    • Hu X., Dai S., Wu W.J., Tan W., Zhu X., Mu J., et al. Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis. Circulation 2007, 116:654-663.
    • (2007) Circulation , vol.116 , pp. 654-663
    • Hu, X.1    Dai, S.2    Wu, W.J.3    Tan, W.4    Zhu, X.5    Mu, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.