메뉴 건너뛰기




Volumn 15, Issue 3, 2013, Pages 267-279

Impact of bone marrow-derived mesenchymal stromal cells on experimental xenogeneic graft-versus-host disease

Author keywords

Graft versus host disease; GVHD; Mesenchymal stromal cells; MSCs; NOD SCID mice; NSG mice

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR GAMMA; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

EID: 84875426087     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1016/j.jcyt.2012.09.003     Document Type: Article
Times cited : (41)

References (45)
  • 1
    • 34248356010 scopus 로고    scopus 로고
    • How I treat refractory acute GVHD
    • Deeg HJ. How I treat refractory acute GVHD. Blood. 2007; 109:4119-26.
    • (2007) Blood. , vol.109 , pp. 4119-4126
    • Deeg, H.J.1
  • 2
    • 20144362213 scopus 로고    scopus 로고
    • Graft-versus-tumor effects after allogeneichematopoietic cell transplantation with nonmyeloablative conditioning
    • Baron F, Maris MB, Sandmaier BM, Storer BE, Sorror M, Diaconescu R, et al. Graft-versus-tumor effects after allogeneichematopoietic cell transplantation with nonmyeloablative conditioning. J Clin Oncol. 2005;23:1993-2003.
    • (2005) J Clin Oncol. , vol.23 , pp. 1993-2003
    • Baron, F.1    Maris, M.B.2    Sandmaier, B.M.3    Storer, B.E.4    Sorror, M.5    Diaconescu, R.6
  • 5
    • 0035760863 scopus 로고    scopus 로고
    • The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation
    • Ho VT, Soiffer RJ. The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation. Blood. 2001;98:3192-204.
    • (2001) Blood. , vol.98 , pp. 3192-3204
    • Ho, V.T.1    Soiffer, R.J.2
  • 8
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P, et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood. 2002;99:3838-43.
    • (2002) Blood. , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6
  • 9
    • 0042740515 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
    • Le Blanc K, Tammik L, Sundberg B, Haynesworth SE, Ringden O. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand J Immunol. 2003;57:11-20.
    • (2003) Scand J Immunol. , vol.57 , pp. 11-20
    • Le Blanc, K.1    Tammik, L.2    Sundberg, B.3    Haynesworth, S.E.4    Ringden, O.5
  • 10
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • Krampera M, Glennie S, Dyson J, Scott D, Laylor R, Simpson E, et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood. 2003;101:3722-9.
    • (2003) Blood. , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3    Scott, D.4    Laylor, R.5    Simpson, E.6
  • 11
    • 17444379357 scopus 로고    scopus 로고
    • Immunobiology of humanmesenchymal stem cells and future use in hematopoietic stem cell transplantation
    • LeBlancK,RingdenO. Immunobiology of humanmesenchymal stem cells and future use in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2005;11:321-34.
    • (2005) Biol Blood Marrow Transplant. , vol.11 , pp. 321-334
    • LeBlanc, K.1    Ringden, O.2
  • 12
    • 35448996504 scopus 로고    scopus 로고
    • Immunomodulation by mesenchymal stem cells and clinical experience
    • Le Blanc K, Ringden O. Immunomodulation by mesenchymal stem cells and clinical experience. J Intern Med. 2007; 262:509-25.
    • (2007) J Intern Med. , vol.262 , pp. 509-525
    • Le Blanc, K.1    Ringden, O.2
  • 13
    • 36348977575 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stromal cells
    • Nauta AJ, Fibbe WE. Immunomodulatory properties of mesenchymal stromal cells. Blood. 2007;110:3499-506.
    • (2007) Blood. , vol.110 , pp. 3499-3506
    • Nauta, A.J.1    Fibbe, W.E.2
  • 14
    • 0036142769 scopus 로고    scopus 로고
    • Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
    • Bartholomew A, Sturgeon C, Siatskas M, Ferrer K, McIntosh K, Patil S, et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol. 2002;30:42-8.
    • (2002) Exp Hematol. , vol.30 , pp. 42-48
    • Bartholomew, A.1    Sturgeon, C.2    Siatskas, M.3    Ferrer, K.4    McIntosh, K.5    Patil, S.6
  • 15
    • 33750559121 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease
    • Yanez R, Lamana ML, Garcia-Castro J, Colmenero I, Ramirez M, Bueren JA. Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease. Stem Cells. 2006;24:2582-91.
    • (2006) Stem Cells. , vol.24 , pp. 2582-2591
    • Yanez, R.1    Lamana, M.L.2    Garcia-Castro, J.3    Colmenero, I.4    Ramirez, M.5    Bueren, J.A.6
  • 16
    • 49649106257 scopus 로고    scopus 로고
    • IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
    • Polchert D, Sobinsky J, Douglas G, Kidd M, Moadsiri A, Reina E, et al. IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease. Eur J Immunol. 2008;38:1745-55.
    • (2008) Eur J Immunol. , vol.38 , pp. 1745-1755
    • Polchert, D.1    Sobinsky, J.2    Douglas, G.3    Kidd, M.4    Moadsiri, A.5    Reina, E.6
  • 17
    • 78649925438 scopus 로고    scopus 로고
    • Mesenchymal stromal cells transiently alter the inflammatory milieu post-transplant to delay graftversus-host disease
    • Christensen ME, Turner BE, Sinfield LJ, Kollar K, Cullup H, Waterhouse NJ, et al. Mesenchymal stromal cells transiently alter the inflammatory milieu post-transplant to delay graftversus-host disease. Haematologica. 2010;95:2102-10.
    • (2010) Haematologica. , vol.95 , pp. 2102-2110
    • Christensen, M.E.1    Turner, B.E.2    Sinfield, L.J.3    Kollar, K.4    Cullup, H.5    Waterhouse, N.J.6
  • 18
    • 33744917000 scopus 로고    scopus 로고
    • Bonemarrowmesenchymal stemcells suppress lymphocyte proliferation in vitro but fail to prevent graft-versushost disease in mice
    • Sudres M, Norol F, Trenado A, Gregoire S, Charlotte F, Levacher B, et al.Bonemarrowmesenchymal stemcells suppress lymphocyte proliferation in vitro but fail to prevent graft-versushost disease in mice. J Immunol. 2006;176:7761-7.
    • (2006) J Immunol. , vol.176 , pp. 7761-7767
    • Sudres, M.1    Norol, F.2    Trenado, A.3    Gregoire, S.4    Charlotte, F.5    Levacher, B.6
  • 19
    • 52049101144 scopus 로고    scopus 로고
    • Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation
    • PrigozhinaTB,Khitrin S, Elkin G, Eizik O,Morecki S, Slavin S. Mesenchymal stromal cells lose their immunosuppressive potential after allotransplantation. Exp Hematol. 2008;36: 1370-6.
    • (2008) Exp Hematol. , vol.36 , pp. 1370-1376
    • Prigozhina, T.B.1    Khitrin, S.2    Elkin, G.3    Eizik, O.4    Morecki, S.5    Slavin, S.6
  • 20
    • 40949106952 scopus 로고    scopus 로고
    • Murine bone marrow derived stromal progenitor cells fail to prevent or treat acute graft-versus-host disease
    • Badillo AT, Peranteau WH, Heaton TE, Quinn C, Flake AW. Murine bone marrow derived stromal progenitor cells fail to prevent or treat acute graft-versus-host disease. Br J Haematol. 2008;141:224-34.
    • (2008) Br J Haematol. , vol.141 , pp. 224-234
    • Badillo, A.T.1    Peranteau, W.H.2    Heaton, T.E.3    Quinn, C.4    Flake, A.W.5
  • 21
    • 79151475166 scopus 로고    scopus 로고
    • Mesenchymal stromal cells fail to prevent acute graft-versus-host disease and graft rejection after dogleukocyte-antigen haploidentical bone marrow transplantation
    • Mielcarek M, Storb R, Georges GE, Golubev L, Nikitine A, Hwang B, et al. Mesenchymal stromal cells fail to prevent acute graft-versus-host disease and graft rejection after dogleukocyte-antigen haploidentical bone marrow transplantation. Biol Blood Marrow Transplant. 2011;17:214-25.
    • (2011) Biol Blood Marrow Transplant. , vol.17 , pp. 214-225
    • Mielcarek, M.1    Storb, R.2    Georges, G.E.3    Golubev, L.4    Nikitine, A.5    Hwang, B.6
  • 22
    • 33745433769 scopus 로고    scopus 로고
    • Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation
    • Miura M, Miura Y, Padilla-Nash HM, Molinolo AA, Fu B, Patel V, et al. Accumulated chromosomal instability in murine bone marrow mesenchymal stem cells leads to malignant transformation. Stem Cells. 2006;24:1095-103.
    • (2006) Stem Cells. , vol.24 , pp. 1095-1103
    • Miura, M.1    Miura, Y.2    Padilla-Nash, H.M.3    Molinolo, A.A.4    Fu, B.5    Patel, V.6
  • 23
    • 85027941877 scopus 로고    scopus 로고
    • Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase
    • Meisel R, Brockers S, Heseler K, Degistirici O, Bulle H, Woite C, et al. Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase. Leukemia. 2011;25:648-54.
    • (2011) Leukemia. , vol.25 , pp. 648-654
    • Meisel, R.1    Brockers, S.2    Heseler, K.3    Degistirici, O.4    Bulle, H.5    Woite, C.6
  • 24
    • 34948892668 scopus 로고    scopus 로고
    • Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation
    • Ball LM, Bernardo ME, Roelofs H, Lankester A, Cometa A, Egeler RM, et al. Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation. Blood. 2007;110: 2764-7.
    • (2007) Blood. , vol.110 , pp. 2764-2767
    • Ball, L.M.1    Bernardo, M.E.2    Roelofs, H.3    Lankester, A.4    Cometa, A.5    Egeler, R.M.6
  • 25
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study
    • Le Blanc K, Frassoni F, Ball L, Locatelli F, Roelofs H, Lewis I, et al. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study. Lancet. 2008;371:1579-86.
    • (2008) Lancet. , vol.371 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3    Locatelli, F.4    Roelofs, H.5    Lewis, I.6
  • 26
    • 40749112327 scopus 로고    scopus 로고
    • The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: Outcome of a pilot clinical study
    • Ning H, Yang F, Jiang M, Hu L, Feng K, Zhang J, et al. The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: Outcome of a pilot clinical study. Leukemia. 2008;22: 593-9.
    • (2008) Leukemia. , vol.22 , pp. 593-599
    • Ning, H.1    Yang, F.2    Jiang, M.3    Hu, L.4    Feng, K.5    Zhang, J.6
  • 27
    • 79951679002 scopus 로고    scopus 로고
    • Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation
    • Bernardo ME, Ball LM, Cometa AM, Roelofs H, Zecca M, Avanzini MA, et al. Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation. Bone Marrow Transplant. 2011;46:200-7.
    • (2011) Bone Marrow Transplant. , vol.46 , pp. 200-207
    • Bernardo, M.E.1    Ball, L.M.2    Cometa, A.M.3    Roelofs, H.4    Zecca, M.5    Avanzini, M.A.6
  • 28
    • 77952584405 scopus 로고    scopus 로고
    • Cotransplantation of mesenchymal stem cells might prevent death from graft-versus-host disease (GVHD) without abrogating graft-versus-tumor effects after HLAmismatched allogeneic transplantation following nonmyeloablative conditioning
    • Baron F, Lechanteur C, Willems E, Bruck F, Baudoux E, Seidel L, et al. Cotransplantation of mesenchymal stem cells might prevent death from graft-versus-host disease (GVHD) without abrogating graft-versus-tumor effects after HLAmismatched allogeneic transplantation following nonmyeloablative conditioning. Biol Blood Marrow Transplant. 2010;16:838-47.
    • (2010) Biol Blood Marrow Transplant. , vol.16 , pp. 838-847
    • Baron, F.1    Lechanteur, C.2    Willems, E.3    Bruck, F.4    Baudoux, E.5    Seidel, L.6
  • 29
    • 77955518690 scopus 로고    scopus 로고
    • Prochymal improves response rates in patients with steroid-refractory acute graft versus host disease (SRGVHD) involving the liver and gut: Results of a randomized, placebo-controlled, multicenter phase III trial in GVHD
    • Martin PJ, Uberti JP, Soiffer RJ, Klingemann H, Waller EK, Daly AS, et al. Prochymal improves response rates in patients with steroid-refractory acute graft versus host disease (SRGVHD) involving the liver and gut: Results of a randomized, placebo-controlled, multicenter phase III trial in GVHD. Biol Blood Marrow Transplant. 2010;16(Suppl. 2): S169-70.
    • (2010) Biol Blood Marrow Transplant. , vol.16 , Issue.SUPPL. 2
    • Martin, P.J.1    Uberti, J.P.2    Soiffer, R.J.3    Klingemann, H.4    Waller, E.K.5    Daly, A.S.6
  • 31
    • 73949156395 scopus 로고    scopus 로고
    • Prolonged ex vivo culture of human bone marrow mesenchymal stem cells influences their supportive activity toward NOD/SCID-repopulating cells and committed progenitor cells of B lymphoid and myeloid lineages
    • Briquet A, Dubois S, Bekaert S, Dolhet M, Beguin Y, Gothot A. Prolonged ex vivo culture of human bone marrow mesenchymal stem cells influences their supportive activity toward NOD/SCID-repopulating cells and committed progenitor cells of B lymphoid and myeloid lineages. Haematologica. 2010;95:47-56.
    • (2010) Haematologica. , vol.95 , pp. 47-56
    • Briquet, A.1    Dubois, S.2    Bekaert, S.3    Dolhet, M.4    Beguin, Y.5    Gothot, A.6
  • 32
    • 33749062024 scopus 로고    scopus 로고
    • Despite inhibition of hematopoietic progenitor cell growth in vitro, the tyrosine kinase inhibitor 278 F. Bruck et al. imatinib does not impair engraftment of human CD133? cells into NOD/SCIDbeta2mNull mice
    • Pirson L, Baron F, Meuris N, Giet O, Castermans E, Greimers R, et al. Despite inhibition of hematopoietic progenitor cell growth in vitro, the tyrosine kinase inhibitor 278 F. Bruck et al. imatinib does not impair engraftment of human CD133? cells into NOD/SCIDbeta2mNull mice. Stem Cells. 2006;24: 1814-21.
    • (2006) Stem Cells. , vol.24 , pp. 1814-1821
    • Pirson, L.1    Baron, F.2    Meuris, N.3    Giet, O.4    Castermans, E.5    Greimers, R.6
  • 33
    • 0347898005 scopus 로고    scopus 로고
    • Quantitative analysis of fetal DNA in maternal plasma and serum: Implications for noninvasive prenatal diagnosis
    • Lo YM, Tein MS, Lau TK, Haines CJ, Leung TN, Poon PM, et al. Quantitative analysis of fetal DNA in maternal plasma and serum: Implications for noninvasive prenatal diagnosis. Am J Hum Genet. 1998;62:768-75.
    • (1998) Am J Hum Genet. , vol.62 , pp. 768-775
    • Lo, Y.M.1    Tein, M.S.2    Lau, T.K.3    Haines, C.J.4    Leung, T.N.5    Poon, P.M.6
  • 35
    • 79551646958 scopus 로고    scopus 로고
    • Thymic recovery after allogeneic hematopoietic cell transplantation with non-myeloablative conditioning is limited to patients younger than 60 years of age
    • Castermans E, Hannon M, Dutrieux J, Humblet-Baron S, Seidel L, Cheynier R, et al. Thymic recovery after allogeneic hematopoietic cell transplantation with non-myeloablative conditioning is limited to patients younger than 60 years of age. Haematologica. 2011;96:298-306.
    • (2011) Haematologica. , vol.96 , pp. 298-306
    • Castermans, E.1    Hannon, M.2    Dutrieux, J.3    Humblet-Baron, S.4    Seidel, L.5    Cheynier, R.6
  • 36
    • 18344410760 scopus 로고    scopus 로고
    • NOD/SCID/gamma(null)(c) mouse: An excellent recipient mouse model for engraftment of human cells
    • Ito M, Hiramatsu H, Kobayashi K, Suzue K, Kawahata M, Hioki K, et al. NOD/SCID/gamma(null)(c) mouse: An excellent recipient mouse model for engraftment of human cells. Blood. 2002;100:3175-82.
    • (2002) Blood. , vol.100 , pp. 3175-3182
    • Ito, M.1    Hiramatsu, H.2    Kobayashi, K.3    Suzue, K.4    Kawahata, M.5    Hioki, K.6
  • 37
    • 84860835823 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: A new tool against graft-versus-host disease?
    • Baron F, Storb R. Mesenchymal stromal cells: A new tool against graft-versus-host disease? Biol Blood Marrow Transplant. 2012;18:822-40.
    • (2012) Biol Blood Marrow Transplant. , vol.18 , pp. 822-840
    • Baron, F.1    Storb, R.2
  • 38
    • 0030813729 scopus 로고    scopus 로고
    • A model of human anti-T-cell monoclonal antibody therapy in SCID mice engrafted with human peripheral blood lymphocytes
    • Tsuchida M, Brown SA, Tutt LM, Tan J, Seehafer DL, Harris JP, et al. A model of human anti-T-cell monoclonal antibody therapy in SCID mice engrafted with human peripheral blood lymphocytes. Clin Transplant. 1997;11: 522-8.
    • (1997) Clin Transplant. , vol.11 , pp. 522-528
    • Tsuchida, M.1    Brown, S.A.2    Tutt, L.M.3    Tan, J.4    Seehafer, D.L.5    Harris, J.P.6
  • 39
    • 0029144933 scopus 로고
    • A human-model of xenogeneic graft-versus-host disease in SCID mice engrafted with human peripheral-blood lymphocytes
    • Sandhu JS, Gorczynski R, Shpitz B, Gallinger S, Nguyen HP, Hozumi N. A human-model of xenogeneic graft-versus-host disease in SCID mice engrafted with human peripheral-blood lymphocytes. Transplantation. 1995;60:179-84.
    • (1995) Transplantation. , vol.60 , pp. 179-184
    • Sandhu, J.S.1    Gorczynski, R.2    Shpitz, B.3    Gallinger, S.4    Nguyen, H.P.5    Hozumi, N.6
  • 40
    • 0042243661 scopus 로고    scopus 로고
    • Complete reconstitution of human lymphocytes from cord blood CD34(?) cells using the NOD/SCID/gamma c(null) mice model
    • Hiramatsu H, Nishikomori R, Heike T, Ito M, Kobayashi K, Katamura K, et al. Complete reconstitution of human lymphocytes from cord blood CD34(?) cells using the NOD/SCID/gamma c(null) mice model. Blood. 2003;102:873-80.
    • (2003) Blood. , vol.102 , pp. 873-880
    • Hiramatsu, H.1    Nishikomori, R.2    Heike, T.3    Ito, M.4    Kobayashi, K.5    Katamura, K.6
  • 41
    • 67649580473 scopus 로고    scopus 로고
    • Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice
    • Ito R, Katano I, Kawai K, Hirata H, Ogura T, Kamisako T, et al. Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice. Transplantation. 2009; 87:1654-8.
    • (2009) Transplantation. , vol.87 , pp. 1654-1658
    • Ito, R.1    Katano, I.2    Kawai, K.3    Hirata, H.4    Ogura, T.5    Kamisako, T.6
  • 42
    • 34548118697 scopus 로고    scopus 로고
    • Mesenchymal stem cells of cord blood origin are effective at preventing but not treating graft-versus-host disease
    • Tisato V, Naresh K, Girdlestone J, Navarrete C, Dazzi F. Mesenchymal stem cells of cord blood origin are effective at preventing but not treating graft-versus-host disease. Leukemia. 2007;21:1992-9.
    • (2007) Leukemia. , vol.21 , pp. 1992-1999
    • Tisato, V.1    Naresh, K.2    Girdlestone, J.3    Navarrete, C.4    Dazzi, F.5
  • 43
    • 85031152492 scopus 로고    scopus 로고
    • Rapamycin delays xenogeneic acute graft versus host disease (AGVHD) in NOD/SCID/Il2R gamma null (NSG) mice: Impact of regulatory T cells
    • Bruck F, Baron F, Dubois S, Briquet A, Hanon-Absil M, Belle L, et al. Rapamycin delays xenogeneic acute graft versus host disease (AGVHD) in NOD/SCID/Il2R gamma null (NSG) mice: Impact of regulatory T cells. Biol Blood Marrow Transplant. 2011;17:S332.
    • (2011) Biol Blood Marrow Transplant. , vol.17
    • Bruck, F.1    Baron, F.2    Dubois, S.3    Briquet, A.4    Hanon-Absil, M.5    Belle, L.6
  • 44
    • 77955349716 scopus 로고    scopus 로고
    • Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis
    • Yoshizaki A, Yanaba K, Yoshizaki A, Iwata Y, Komura K, Ogawa F, et al. Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis. Arthritis Rheum. 2010;62:2476-87.
    • (2010) Arthritis Rheum. , vol.62 , pp. 2476-2487
    • Yoshizaki, A.1    Yanaba, K.2    Yoshizaki, A.3    Iwata, Y.4    Komura, K.5    Ogawa, F.6
  • 45
    • 34248213189 scopus 로고    scopus 로고
    • IL-10-transduced bone marrow mesenchymal stem cells can attenuate the severity of acute graft-versus-host disease after experimental allogeneic stem cell transplantation
    • Min CK, Kim BG, Park G, Cho B, Oh IH. IL-10-transduced bone marrow mesenchymal stem cells can attenuate the severity of acute graft-versus-host disease after experimental allogeneic stem cell transplantation. Bone Marrow Transplant. 2007;39:637-45.
    • (2007) Bone Marrow Transplant. , vol.39 , pp. 637-645
    • Min, C.K.1    Kim, B.G.2    Park, G.3    Cho, B.4    Oh, I.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.