Low-dose of multi-glycoside of Tripterygium wilfordii Hook. f., a natural regulator of TGF-β1/Smad signaling activity improves adriamycin-induced glomerulosclerosis in vivo

Journal of Ethnopharmacology

Volumn 151, Issue 3, 2014, Pages 1079-1089

  Wan, Yi Gang ^a   Che, Xiao Yan ^a   Sun, Wei ^b   Huang, Yan Ru ^c   Meng, Xian Jie ^c   Chen, Hao Li ^c   Shi, Xi Miao ^c   Tu, Yue ^c   Wu, Wei ^a   Liu, Ying Lu ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b AFFILIATED HOSPITAL OF NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Adriamycin induced nephropathy; Glomerulosclerosis; Multi glycoside of Tripterygium wilfordii Hook. f.; Phosphorylated Smad2 3; Smad7; Transforming growth factor 1

Indexed keywords

ADR; ADRIAMYCIN; ADRIAMYCIN-INDUCED NEPHROPATHY; ADRN; ALB; BCA; BICINCHONINIC ACID; BLOOD UREA NITROGEN; BODY WEIGHT; BOVINE SERUM ALBUMIN; BSA; BUN; BW; CHRONIC KIDNEY DISEASE; CKD; ECM; EDTA; ETHYLENEDIAMINETETRAACETIC ACID; EXTRACELLULAR MATRIX; FITC; FLUORESCEINE ISOTHIOCYANATE; FOCAL SEGMENTAL GLOMERULOSCLEROSIS; FSGS; GLOMERULOSCLEROSIS; GS; GTW; IF; IMMUNOFLUORESCENCE; KIDNEY WEIGHT; KW; MC; MESANGIAL CELLS; MULTI-GLYCOSIDE OF TRIPTERYGIUM WILFORDII HOOK. F.; P-SMAD; PAS; PB; PBS; PERIODIC ACID-SCHIFF; PHOSPHATE BUFFER; PHOSPHATE BUFFER SOLUTION; PHOSPHORYLATED SMAD; PHOSPHORYLATED-SMAD2/3; PI; POLYVINYLIDENE FLUORIDE; PROTEASE INHIBITORS; PVDF; SCR; SDS-PAGE; SERUM ALBUMIN; SERUM CREATININE; SMAD7; SODIUM DODECYL SULFATE-POLYACRYLAMIDE GEL ELECTROPHORESIS; TCM; TGF-Β1; TRADITIONAL CHINESE MEDICINE; TRANSFORMING GROWTH FACTOR-Β1; UPRO; URINARY PROTEIN EXCRETION; Α-SMA; Α-SMOOTH MUSCLE ACTIN;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; DOXORUBICIN; FEMALE; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; GLYCOSIDES; KIDNEY GLOMERULUS; PHYTOTHERAPY; PROTEINURIA; RATS; RATS, WISTAR; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1; TRIPTERYGIUM;

EID: 84895070042     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.12.005     Document Type: Article

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