Role of mesangial cell damage in progressive renal disease

Kidney and Blood Pressure Research

Volumn 22, Issue 1-2, 1999, Pages 5-12

  Shimizu, Fujio ^a   Kawachi, H ^a   Orikasa, M ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

ATS model; Mesangioproliferative glomerulonephritis; Monoclonal antibody; Progressive renal diseases; Thy 1.1 molecule

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL PROLIFERATION; FEMALE; KIDNEY DISEASE; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBODIES, MONOCLONAL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GLOMERULAR MESANGIUM; KIDNEY DISEASES;

EID: 0032978263     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000025903     Document Type: Article

References (34)

1. Kriz W, Gretz N, Lemley KV: Progression of glomerular diseases: Is the podocyte the culprit? Kidney Int 1998;54:687-697.
2. Floege J, Hackmann B, Kliem V, Kriz W, Alpers CE, Johnson RJ, Kühn KW, Koch KM, Brunkhorst R: Age-related glomeruloscherosis and interstitial fibrosis in Milan normotensive rats: A podocyte disease. Kidney Int 1997;51: 230-243.
3. Courser WG: Pathogenesis of glomerular damage in glomerulonephritis. Nephrol Dial Transplant 1998;13(suppl 1):10-15.
4. Floege J, Gröne HJ: Glomerular cells in the progression of human and experimental nephropathies; in Grunfeld JP, Bach JF, Kreis H, Maxwell MH (eds): Adv Nephrol. St. Louis, Mosby, 1997. vol 27, pp 15-37.
5. Wilson CB: Renal response to immunologic glomerular injury; in Brenner BM (ed): The Kidney. Philadelphia. Saunders, 1996. pp 1253-1391.
6. Sterzel RB, Rupprecht HD: Glomerular mesangial cells; in Neilson EG. Couser WG (eds): Immunologic Renal Diseases. Philadelphia, Lippincott-Raven, 1997. pp 595-626.
7. Kawachi H. Orikasa M. Matsui K, Iwanaga T, Toyabe S, Oite T, Shimizu F: Epitope-specific induction of mesangial lesions with proteinuria by a MoAb against mesangial cell surface. Clin Exp Immunol 1992;88:399-404.
8. Kawachi H. Orikasa M. Matsui K, Iwanaga T, Toyabe S, Morioka T. Oite T, Shimizu F: Induction of proteinuria and morphological changes in the rat by a monoclonal antibody against mesangial cell surface: in Oite T (ed): Structural Basis for Glomerular Dysfunction. Niigata. Nishimura. 1991, pp 105-112.
9. Orikasa M, Matsui K, Oite T, Shimizu F: Massive proteinuria induced in rats by a single intravenous injection of a monoclonal antibody. J Immunol 1988;141:807-814.
10. Oite T, Saito M, Suzuki Y. Arii T, Morioka T, Shimizu F: A specific Thy-1 molecular epitope expressed on rat mesangial cells. Exp Nephrol 1996;4:350-360.
11. Bagchus WM, Hoedemaeker PhJ, Rozing J, Bakker WW: Glomerulonephritis induced by monoclonal anti-Thy1.1 antibodies. Lab Invest 1986;55:680-687.
12. Kawachi H, Oite T, Shimizu F: Quantitative study of mesangial injury with proteinuria induced by monoclonal antibody 1-22-3. Clin Exp Immunol 1993;92:342-346.
13. Paul LC, Rennke HG, Milford EL, Carpenter CB: Thy-1.1 in glomeruli of rat kidneys. Kidney Int 1984;25:771-777.
14. 2+-independent mechanism. J Exp Med 1991;173:515-518.
15. Narisawa-Saito M, Yamanashi Y, Morioka T, Oite T, Shimizu F: Thy-1 molecule associates with protein tyrosine kinase(s) in rat mesangial cells. Clin Exp Immunol 1996;106:86-90.
16. Narisawa-Saito M, Kimura S, Fujiwara N, Oite T, Shimoji K, Shimizu F: Thy-1-mediated phosphatidylinositol turnover in cultured rat glomerular mesangial cell. J Cell Physiol 1996;168:705-710.
17. Gunter KC, Malek TR, Shevach EM: T cell-activating properties of an anti-Thy-1 monoclonal antibody: Possible analogy to CT3/LEV-4. J Exp Med 1984;159:716-730.
18. Dreverova L, Draber P: Functional expression of the endogenous Thy-1 gene and the transfected murine Thy-1. 2 gene in rat basophilic leukemia cells Eur J Immunol 1991;21:1583-1590.
19. Nakayama H, Oite T, Kawachi H, Morioka T, Kobayashi H, Orikasa M, Arakawa M, Shimizu F: Comparative nephritogenicity of two monoclonal antibodies that recognize different epitopes of rat Thy-1.1 molecule. Nephron 1998;78:453-463.
20. Kitamura M, Taylor S, Unwin R, Burton S, Shimizu F, Fine LG: Gene transfer into the rat renal glomerulus via a mesangial cell vector: Site-specific delivery, in situ amplification and sustained expression of an exogenous gene in vivo. J Clin Invest 1994;94:497-505.
21. Kawachi H, Iwanaga T, Toyabe S, Oite T, Shimizu F: Mesangial sclerotic change with persistent proteinuria in rats after two consecutive injections of monoclonal antibody 1-22-3. Clin Exp Immunol 1992;90:129-134.
22. Cheng QL, Orikasa M, Morioka T, Kawachi H, Chen XM. Oite T, Shimizu F: Progressive renal lesions induced by administration of monoclonal antibody 1-22-3 to unilaterally nephrectomized rats. Clin Exp Immunol 1995;102:181-185.
23. Shimizu F, Fukagawa M, Yamauchi S, Tanigawa M, Komemushi S, Margolin SB, Kurokawa K: Pirfenidone prevents the progression of irreversible glomerular sclerotic lesions in rats. Nephrology 1997;3:315-322.
24. Kawachi H, Kurihara H, Topham P, Brown D, Shia MA, Orikasa M. Shimizu F, Salant DJ: Slit diaphragm-reactive nephritogenic Mab 5-1-6 alters expression of ZO-1 in rat podocytes. Am J Physiol 1997;273:F984-F993.
25. Kawachi H, Kobayashi H, Natori Ya, Natori Yu, Yamamoto T, Takeya M, Orikasa M, Shimizu F: Monocyte accumulation attracted by MCP-1 have a beneficial role to prevent irreversible mesangial alterations (abstract). J Am Soc Nephrol 1998;9:459A.
26. Floege J, Alpers CE, Burns MW, Pritzl P, Gordon K, Couser WG, Johnson RJ: Glomerular cells, extracellular matrix accumulation and the development of glomerulosclerosis in the remnant kidney model. Lab Invest 1992;66: 485-497.
27. Floege J, Burns MW, Alpers CE, Yoshimura A, Pritzl P, Gordon K, Seifert RA, Bowen Pope DF, Couser WG, Johnson RJ: Glomerular cell proliferation and PDGF expression preceede glomerulosclerosis in the remnant kidney model. Kidney Int 1992;41:297-309.
28. Cattel V: Macrophages in acute glomerular inflammation. Kidney Int 1994;45:945-952.
29. Kobayashi H. Orikasa M, Naito M, Kawasaki K, Oite T, Kawachi H, Yamashita A, Takeya M, Nihei H, Shimizu F: Detailed analysis of phenotypes of macrophages infiltrating glomeruli in rat anti-Thy-1 nephritis. Nephron 1997;77:333-339.
30. Nakayama M. Okuda S. Tamaki K, Shimizu F, Kawachi H, Ando T, Yanagida T, Fujishima M: Roles of TGF-β and latent TGF-β-binding protein in glomerulosclerosis induced by two consecutive injections of monoclonal antibody 1-22-3 in rats. Nephron 1997;76:82-89.
31. Morita Y, Nomura A, Yuzawa Y, Nishikawa K, Hotta N. Shimizu F, Matsuo S: The role of complement in the pathogenesis of tubulointerstitial lesions in rat mesangial proliterative glomerulonephritis. J Am Soc Nephrol 1997;8: 1363-1372.
32. Nakamura T, Obata J, Onizuka M, Kimura H, Ohno S, Yoshida Y, Kawachi H, Shimizu F: Candersartan prevents the progression of mesangioproliferative nephritis in rats. Kidney Int 1997;52:S226-S228.
33. Nakamura T, Obata J, Kimura H, Ohno S, Yoshida Y, Kawachi H, Shimizu F: Blocking angiotensin-II ameliorates proteinuria and glomerular lesions in progressive mesangioproliferative glomerulonephritis. Kidney Int, in press.
34. Li P, Kawachi H, Orikasa M, SHI ZS, Shimizu F: Effect of Sairei-to on irreversible glomerular sclerotic lesions in rats. Nephrology 1998; 4:49-56.