Improved separation of bovine serum albumin and lactoferrin mixtures using charged ultrafiltration membranes

Separation and Purification Technology

Volumn 125, Issue , 2014, Pages 163-169

  Valiño, Virginia ^a   San Román, Ma Fresnedo ^a   Ibañez, Raquel ^a   Ortiz, Inmaculada ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

BSA; Charged membranes; Isoelectric point; LF; Membrane fouling; Protein separation

Indexed keywords

EID: 84894588569     PISSN: 13835866     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seppur.2014.01.023     Document Type: Article

References (49)

1. A. Saxena, B.P. Tripathi, M. Kumar, and V.K. Shahi Membrane-based techniques for the separation and purification of proteins: an overview Adv. Colloid Interface Sci. 145 2009 1 22
2. C. Boi, and G.C. Sarti Development and characterization of affinity membranes for immunoglobulin purification Sep. Sci. Technol. 42 2007 2987 3001 (Pubitemid 350093127)
3. T.R. Gaborski, J.L. Snyder, C.C. Striemer, D.Z. Fang, M. Hoffman, P.M. Fauchet, and J.L. McGrath High-performance separation of nanoparticles with ultrathin porous nanocrystalline silicon membranes ACS Nano. 4 2010 6973 6981
4. D. Lucas, M. Rabiller-Baudry, L. Millesime, B. Chaufer, and G. Daufin Extraction of α-lactalbumin from whey protein concentrate with modified inorganic membranes J. Membr. Sci. 148 1998 1 12 (Pubitemid 28529477)
5. B. Cheang, and A.L. Zydney Separation of α-lactalbumin and β-lactoglobulin using membrane ultrafiltration Biotechnol. Bioeng. 83 2003 201 209 (Pubitemid 36734133)
6. B. Cheang, and A.L. Zydney A two-stage ultrafiltration process for fractionation of whey protein isolate J. Membr. Sci. 231 2004 159 167 (Pubitemid 38221482)
7. L. Bazinet, D. Ippersiel, and B. Mahdavi Fractionation of whey proteins by bipolar membrane electroacidification Innovative Food Sci. Emerg. Technol. 5 2004 17 25 (Pubitemid 38304976)
8. S. Metsämuuronen, and M. Nyström Evaluation of six flat sheet ultrafiltration membranes for fractionation of whey proteins Desalination 200 2006 290 291 (Pubitemid 44173607)
9. S. Cowan, and S. Ritchie Modified polyethersulfone (PES) ultrafiltration membranes for enhanced filtration of whey proteins Sep. Sci. Technol. 42 2007 2405 2418 (Pubitemid 47567329)
10. S. Galier, and H.R.D. Balmann The electrophoretic membrane contactor: a mass-transfer-based methodology applied to the separation of whey proteins Sep. Purif. Technol. 77 2011 237 244
11. J. Toro-Sierra, A. Tolkach, and U. Kulozik Fractionation of α-lactalbumin and β-lactoglobulin from whey protein isolate using selective thermal aggregation, an optimized membrane separation procedure and resolubilization techniques at pilot plant scale Food Bioprocess Technol. 6 2013 1032 1043
12. P.S. Cheow, E.Z.C. Ting, M.Q. Tan, and C.S. Toh Transport and separation of proteins across platinum-coated nanoporous alumina membranes Electrochim. Acta 53 2008 4669 4673
13. R.W. Field, K.F. Md Yunos, and Z. Cui Separation of proteins using sandwich membranes Desalination 245 2009 597 605
14. K.F. Md Yunos, and R.W. Field Rejection amplification in the ultrafiltration of binary protein mixtures using sandwich configurations Chem. Eng. Process. 47 2008 1053 1060 (Pubitemid 351680309)
15. J.H. Cheng, Y. Li, T.S. Chung, S.B. Chen, and W.B. Krantz High-performance protein separation by ion exchange membrane portioned free-flow isoelectric focusing system Chem. Eng. Sci. 63 2008 2241 2251
16. S. Rao, and A.L. Zydney High-resolution protein separation using affinity ultrafiltration with small charged ligands J. Membr. Sci. 280 2006 781 789
17. R. van Reis, J.M. Brake, J. Charkoudian, D.B. Burns, and A.L. Zydney High-performance tangential filtration using charged membranes J. Membr. Sci. 159 1999 133 142 (Pubitemid 29243851)
18. M.M. Rohani, and A.L. Zydney Protein transport through zwitterionic ultrafiltration membranes J. Membr. Sci. 397-398 2012 1 8
19. M. Nyström, P. Aimar, S. Luque, M. Kulovaara, and S. Metsämuuronen Fractionation of model proteins using their physiochemical properties Colloids Surf. 138 1998 185 205 (Pubitemid 28267218)
20. N. Ndiaye, Y. Pouliot, L. Saucier, L. Beaulieu, and L. Bazinet Electroseparation of bovine lactoferrin from model and whey solutions Sep. Purif. Technol. 74 2010 93 99
21. L. Baró, J. Jiménez, A. Martínez-Pérez, and J. Bouza Péptidos y proteínas de la leche con propiedades funcionales Ars. Pharm. 42 2001 135 145
22. M.P. Mier, R. Ibañez, and I. Ortiz Influence of process variables on the production of bovine milk casein by electrodialysis with bipolar membranes Biochem. Eng. J. 40 2008 304 311
23. M.C. Almécija, R. Ibañez, A. Guadix, and E.M. Guadix Influence of pH in the recovery of lactoferrin from whey with ceramic membranes Desalination 200 2006 475 476 (Pubitemid 44173486)
24. L. Voswinkel, and U. Kulozik Fractionation of whey proteins by means of membrane adsorption chromatography Procedia Food Sci. 1 2011 900 907
25. G. Brisson, M. Britten, and Y. Pouliot Effect of iron saturation on the recovery of lactoferrin in rennet whey coming from hear-treated skin milk J. Dairy Sci. 90 2007 2655 2664 (Pubitemid 350049658)
26. J. Noel, A. Prokop, and R.D. Tanner Foam fractionation of a dilute solution of bovine lactoferrin Appl. Biochem. Biotechnol. 98-100 2002 395 402 (Pubitemid 34457436)
27. J.R. Ku, and P. Stroeve Protein diffusion in charged nanotubes: "On-Off" behavior of molecular transport Langmuir 20 2004 2030 2032
28. S.A. Moore, B.F. Anderson, C.R. Groom, M. Haridas, and E.N. Baker Three-dimensional structure of diferric bovine lactoferrin at 2.8 Å resolution J. Mol. Biol. 274 1997 222 236 (Pubitemid 27520608)
29. P.G. Thakurta, D. Choudhury, R. Dasgupta, and J.K. Dattagupta Tertiary structural changes associated with iron binding and release in hen serum transferrin: a crystallographic and spectroscopic study Biochem. Biophys. Res. Commun. 316 2004 1124 1131 (Pubitemid 38369069)
30. T. Arakawa, and Y. Kita Stabilizing effects of caprylate and acetyltryptophanate on heat-induced aggregation of bovine serum albumin Biochim. Biophys. Acta 1479 2000 32 36 (Pubitemid 30345621)
31. L. Sánchez, J.M. Peiró, R. Oria, H. Castillo, J.H. Brock, and M. Calvo Kinetic parameters for the heat denaturation of bovine lactoferrin in milk, and its effect on interaction with monocytes Adv. Exp. Med. Biol. 357 1994 253 257
32. H.A. Patel, Studies on Heat-and Pressure-Induced Interactions of Milk Proteins. PhD Thesis, Massey University. New Zealand, 2007.
33. V. Adam, O. Zitka, P. Dolezal, L. Zeman, A. Horna, J. Hubalek, J. Sileny, S. Krizkova, L. Trnkova, and R. Kivek Lactoferrin isolation using monolithic column coupled with spectrometric or micro-amperometric detector Sensors 8 2008 464 487
34. N.S. Pujar, and A.L. Zydney Electrostatic and Electrokinetic interactions during protein transport through narrow pore membranes Ind. Eng. Chem. Res. 33 1994 2473 2482
35. Zetasizer APS User Manual. December 2013. Manual on-< http://www.malvern.com >.
36. R. van Reis. Charged Filtration Membranes and uses Therefore, USA Patent WO 01/08792 A2, 2001.
37. C. Baldasso, T.C. Barros, and I.C. Tessaro Concentration and purification of whey proteins by ultrafiltration Desalination 278 2011 381 386
38. A. Rektor, and G. Vatai Membrane filtration of Mozzarella whey Desalination 162 2004 279 286 (Pubitemid 38473790)
39. R. Atra, G. Vatai, E. Bekassy-Molhar, and A. Balint Investigation of ultra and nanfiltration for utilization of whey protein and lactose J. Food Eng. 67 2005 325 332
40. K.W.K. Yee, D.E. Wiley, and J. Bao Whey protein concentrate production by continuous ultrafiltration: Operability under constant operating conditions J. Membr. Sci. 290 2007 125 137 (Pubitemid 46216633)
41. A. Salis, M. Boström, L. Medda, F. Cugia, B. Barse, D.F. Parsons, B.W. Ninham, and M. Monduzzi Measurements and Theoretical Interpretation of Points of Zero Charge/Potential of BSA Protein Langmuir 27 2011 11597 11604
42. F. Zhang, M.W.A. Skoda, R.M.J. Jacobs, R.A. Martin, C.M. Martin, and F. Schreibe Protein Interactions Studied by SAXS: Effect of Ionic Strength and Protein Concentration for BSA in Aqueous Solutions J. Phys. Chem. B. 111 2007 251 259 (Pubitemid 46277989)
43. I. Mela, E. Aumaitre, A.M. Williamson, and G.E. Yakubov Charge reversal by salt-induced aggregation in aqueous lactoferrin solutions Colloid Surf. B 78 2010 53 60
44. B. Jachimska, and A. Pajor Physico-chemical characterization of bovine serum albumin in solution and as deposited on surfaces Bioelectrochemistry 87 2012 138 146
45. B.D. Bowes, H. Koku, K.J. Czymmek, and A.M. Lenhoff Protein adsorption and transport in dextran-modified ionexchange media I. Adsorption J Chromatogr. A. 1216 2009 7774 7784
46. H.C. Mahler, W. Friess, U. Grauschopf, and S. Kiese Protein aggregation: pathways, induction factors and analysis J. Pharm. Sci. 98 2009 2909 2933
47. F. Lampreave, A. Piñeiro, J.H. Brock, H. Castillo, L. Sánchez, and M. Calvo Interaction of bovine lactoferrin with other proteins of milk whey Int. J. Biol. Macromol. 12 1990 2 5 (Pubitemid 20120020)
48. P.R. Babu, and V.G. Gaikar Membrane characteristics as determinant in fouling of UF membranes Sep. Purif. Technol. 24 2001 23 34 (Pubitemid 32787173)
49. A. Thekkedath, W.M. Naceur, K. Kecili, M. Sbai, A. Elana, L. Auret, H. Suty, C. Machinal, and M. Pontie Macroscopic and microscopic characterizations of a cellulosic ultrafiltration (UF) membrane fouled by a humic acid cake deposit: First step for intensification of reverse osmosis (RO) pre-treatments C. R. Chim. 10 2007 803 812