Insight into structure-function relationship in phenol-soluble modulins using an alanine screen of the phenol-soluble modulin (PSM) α3 peptide

FASEB Journal

Volumn 28, Issue 1, 2014, Pages 153-161

  Cheung, Gordon Y C ^a   Kretschmer, Dorothee ^b   Queck, Shu Y ^a,d   Joo, Hwang Soo ^a   Wang, Rong ^a,e   Duong, Anthony C ^a   Nguyen, Thuan H ^a   Bach, Thanh Huy L ^a   Porter, Adeline R ^c   DeLeo, Frank R ^c   Peschel, Andreas ^b   Otto, Michael ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d U S MEAT ANIMAL RESEARCH CENTER   (United States)

^e Biomerieux Singapore Pte Ltd   (Singapore)

Author keywords

Biofilm; Hemolysis; Inflammation; Neutrophils; Staphylococcus aureus; Toxins

Indexed keywords

ALANINE; AMINO ACID; LYSINE; PEPTIDE; PHENOL DERIVATIVE; PHENOL SOLUBLE MODULIN ALPHA3 PEPTIDE; RECEPTOR; UNCLASSIFIED DRUG; PHENOL; TOXIN; VIRULENCE FACTOR;

ALPHA HELIX; ANIMAL EXPERIMENT; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL VIRULENCE; BIOFILM; CONTROLLED STUDY; CYTOLYSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL CULTURE; CHEMISTRY; CIRCULAR DICHROISM; DRUG EFFECT; FLOW CYTOMETRY; HEMOLYSIS; INFLAMMATION; METABOLISM; MICROBIOLOGY; NEUTROPHIL; PATHOGENICITY; PERITONITIS;

BIOFILM; HEMOLYSIS; INFLAMMATION; NEUTROPHILS; STAPHYLOCOCCUS AUREUS; TOXINS;

ANIMALS; BIOFILMS; CELLS, CULTURED; CIRCULAR DICHROISM; FLOW CYTOMETRY; HEMOLYSIS; HUMANS; MICE; NEUTROPHILS; PEPTIDES; PERITONITIS; PHENOL; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRULENCE FACTORS;

EID: 84894564599     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-232041     Document Type: Article

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