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Volumn 47, Issue 2, 2014, Pages 134-140

Pemphigus vulgaris autoimmune globulin induces Src-dependent tyrosine-phosphorylation of plakophilin 3 and its detachment from desmoglein 3

Author keywords

Acantholysis; Desmosome; Keratinocytes; Pemphigus vulgaris; Plakophilin 3; Src kinase

Indexed keywords

AUTOANTIBODIES; CELL ADHESION; CELL COMMUNICATION; CELL LINE; DESMOGLEIN 3; EPIDERMIS; GENE EXPRESSION REGULATION; HUMANS; IMMUNOGLOBULIN G; KERATINOCYTES; PEMPHIGUS; PHOSPHORYLATION; PLAKOPHILINS; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TYROSINE;

EID: 84894534807     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.3109/08916934.2013.866100     Document Type: Article
Times cited : (25)

References (39)
  • 1
    • 84984774604 scopus 로고    scopus 로고
    • Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome
    • McGrath, J. A., J. R. McMillan, C. S. Shemanko, et al. (1997). Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome. Nat. Genet. 17: 240-244.
    • (1997) Nat. Genet. , vol.17 , pp. 240-244
    • McGrath, J.A.1    McMillan, J.R.2    Shemanko, C.S.3
  • 2
    • 84894554026 scopus 로고    scopus 로고
    • Pathophysiology of the desmosome
    • Trivandrum, India.
    • Cirillo, N. (2009). Pathophysiology of the desmosome. Research Signpost, Trivandrum, India. pp. 202.
    • (2009) Research Signpost , pp. 202
    • Cirillo, N.1
  • 3
    • 33644854767 scopus 로고    scopus 로고
    • Identification of the junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules
    • Hofmann, I., M. Casella, M. Schnolzer, et al. (2006). Identification of the junctional plaque protein plakophilin 3 in cytoplasmic particles containing RNA-binding proteins and the recruitment of plakophilins 1 and 3 to stress granules. Mol. Biol. Cell. 17: 1388-1398.
    • (2006) Mol. Biol. Cell. , vol.17 , pp. 1388-1398
    • Hofmann, I.1    Casella, M.2    Schnolzer, M.3
  • 4
    • 70349878700 scopus 로고    scopus 로고
    • Desmosomal interactome in keratinocytes: A systems biology approach leading to an understanding of the pathogenesis of skin disease
    • Cirillo, N., and S. S. Prime. (2009). Desmosomal interactome in keratinocytes: A systems biology approach leading to an understanding of the pathogenesis of skin disease. Cell. Mol. Life Sci. 66: 3517-3533.
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 3517-3533
    • Cirillo, N.1    Prime, S.S.2
  • 5
    • 43749116674 scopus 로고    scopus 로고
    • Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation
    • Sklyarova, T., S. Bonné, P. DHooge, et al. (2008). Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation. J. Invest. Dermatol. 128: 1375-1385.
    • (2008) J. Invest. Dermatol. , vol.128 , pp. 1375-1385
    • Sklyarova, T.1    Bonné, S.2    Dhooge, P.3
  • 6
    • 34250354415 scopus 로고    scopus 로고
    • Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: Characterization of novel signaling pathways downstream of pemphigus vulgaris antigens
    • Chernyavsky, A. I., J. Arredondo, Y. Kitajima, et al. (2007). Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: Characterization of novel signaling pathways downstream of pemphigus vulgaris antigens. J. Biol. Chem. 282: 13804-13812.
    • (2007) J. Biol. Chem. , vol.282 , pp. 13804-13812
    • Chernyavsky, A.I.1    Arredondo, J.2    Kitajima, Y.3
  • 7
    • 79551488771 scopus 로고    scopus 로고
    • Deregulation of PERK in the autoimmune disease pemphigus vulgaris occurs via IgG-independent mechanisms
    • Lanza, A., M. Lanza, R. Santoro, et al. (2011). Deregulation of PERK in the autoimmune disease pemphigus vulgaris occurs via IgG-independent mechanisms. Br. J. Dermatol. 164: 336-343.
    • (2011) Br. J. Dermatol. , vol.164 , pp. 336-343
    • Lanza, A.1    Lanza, M.2    Santoro, R.3
  • 9
    • 0347087440 scopus 로고    scopus 로고
    • Pemphigus vulgaris IgG and methylprednisolone exhibit reciprocal effects on keratinocytes
    • Nguyen, V. T., J. Arredondo, A. I. Chernyavsky, et al. (2004). Pemphigus vulgaris IgG and methylprednisolone exhibit reciprocal effects on keratinocytes. J. Biol. Chem. 279: 2135-2146.
    • (2004) J. Biol. Chem. , vol.279 , pp. 2135-2146
    • Nguyen, V.T.1    Arredondo, J.2    Chernyavsky, A.I.3
  • 10
    • 41249092968 scopus 로고    scopus 로고
    • Differential coupling of M1 muscarinic and alpha7 nicotinic receptors to inhibition of pemphigus acantholysis
    • Chernyavsky, A. I., J. Arredondo, T. Piser, et al. (2008). Differential coupling of M1 muscarinic and alpha7 nicotinic receptors to inhibition of pemphigus acantholysis. J. Biol. Chem. 283: 3401-3408.
    • (2008) J. Biol. Chem. , vol.283 , pp. 3401-3408
    • Chernyavsky, A.I.1    Arredondo, J.2    Piser, T.3
  • 11
    • 34248232439 scopus 로고    scopus 로고
    • Defining the involvement of proteinases in pemphigus vulgaris: Evidence of matrix metalloproteinase-9 overexpression in experimental models of disease
    • Cirillo N., M. Lanza, L. Rossiello, et al. (2007). Defining the involvement of proteinases in pemphigus vulgaris: Evidence of matrix metalloproteinase-9 overexpression in experimental models of disease. J. Cell. Physiol. 212: 36-41.
    • (2007) J. Cell. Physiol. , vol.212 , pp. 36-41
    • Cirillo, N.1    Lanza, M.2    Rossiello, L.3
  • 12
    • 34547950565 scopus 로고    scopus 로고
    • If pemphigus vulgaris IgG are the cause of acantholysis, new IgG-independent mechanisms are the concause
    • Cirillo, N., M. Lanza, F. Femiano, et al. (2007). If pemphigus vulgaris IgG are the cause of acantholysis, new IgG-independent mechanisms are the concause. J. Cell. Physiol. 212: 563-567.
    • (2007) J. Cell. Physiol. , vol.212 , pp. 563-567
    • Cirillo, N.1    Lanza, M.2    Femiano, F.3
  • 13
    • 34249310581 scopus 로고    scopus 로고
    • Pemphigus vulgaris immunoglobulin G can recognize a 130 000 MWantigen other than desmoglein 3 on peripheral blood mononuclear cell surface
    • Cirillo, N., F. Gombos, and A. Lanza. (2007). Pemphigus vulgaris immunoglobulin G can recognize a 130 000 MWantigen other than desmoglein 3 on peripheral blood mononuclear cell surface. Immunology 121: 377-382.
    • (2007) Immunology , vol.121 , pp. 377-382
    • Cirillo, N.1    Gombos, F.2    Lanza, A.3
  • 14
    • 0023852747 scopus 로고
    • Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line
    • Boukamp, P., R. T. Petrussevska, D. Breitkreutz, et al. (1988). Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell. Biol. 106: 761-771.
    • (1988) J. Cell. Biol. , vol.106 , pp. 761-771
    • Boukamp, P.1    Petrussevska, R.T.2    Breitkreutz, D.3
  • 15
    • 28244492845 scopus 로고    scopus 로고
    • Novel mechanisms of target cell death and survival and of therapeutic action of IVIg in Pemphigus
    • Arredondo, J., A. I. Chernyavsky, A. Karaouni, and S. A. Grando. (2005). Novel mechanisms of target cell death and survival and of therapeutic action of IVIg in Pemphigus. Am. J. Pathol. 167: 1531-1544.
    • (2005) Am. J. Pathol. , vol.167 , pp. 1531-1544
    • Arredondo, J.1    Chernyavsky, A.I.2    Karaouni, A.3    Grando, S.A.4
  • 16
    • 38649137691 scopus 로고    scopus 로고
    • The most widespread desmosomal cadherin, desmoglein 2, is a novel target of caspase 3-mediated apoptotic machinery
    • Cirillo, N., M. Lanza, A. De Rosa, et al. (2008). The most widespread desmosomal cadherin, desmoglein 2, is a novel target of caspase 3-mediated apoptotic machinery. J. Cell. Biochem. 103: 598-606.
    • (2008) J. Cell. Biochem. , vol.103 , pp. 598-606
    • Cirillo, N.1    Lanza, M.2    De Rosa, A.3
  • 17
    • 0032526941 scopus 로고    scopus 로고
    • Tyrosine phosphorylation and Src-family kinases control keratinocyte cell-cell adhesion
    • Calautti, E., S. Cabodi, P. L. Stein, et al. (1998). Tyrosine phosphorylation and Src-family kinases control keratinocyte cell-cell adhesion. J. Cell. Biol. 141: 1449-1465.
    • (1998) J. Cell. Biol. , vol.141 , pp. 1449-1465
    • Calautti, E.1    Cabodi, S.2    Stein, P.L.3
  • 18
    • 79951518111 scopus 로고    scopus 로고
    • Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3
    • Jennings, J. M., D. K. Tucker, M. D. Kottke, et al. (2011). Desmosome disassembly in response to pemphigus vulgaris IgG occurs in distinct phases and can be reversed by expression of exogenous Dsg3. J. Invest. Dermatol. 131: 706-718.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 706-718
    • Jennings, J.M.1    Tucker, D.K.2    Kottke, M.D.3
  • 19
    • 0035858871 scopus 로고    scopus 로고
    • A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris
    • Caldelari, R., A. De Bruin, D. Baumann, et al. (2001). A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris. J. Cell. Biol. 153: 823-834.
    • (2001) J. Cell. Biol. , vol.153 , pp. 823-834
    • Caldelari, R.1    De Bruin, A.2    Baumann, D.3
  • 20
    • 84859302584 scopus 로고    scopus 로고
    • Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues
    • Munoz, W. A., M. Kloc, K. Cho, et al. (2012). Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues. PLoS One 7: E34342.
    • (2012) PLoS One , vol.7
    • Munoz, W.A.1    Kloc, M.2    Cho, K.3
  • 21
    • 84862023922 scopus 로고    scopus 로고
    • Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis
    • Khapare, N., S. T. Kundu, L. Sehgal, et al. (2012). Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis. PLoS One 7: E38561.
    • (2012) PLoS One , vol.7
    • Khapare, N.1    Kundu, S.T.2    Sehgal, L.3
  • 22
    • 0029894045 scopus 로고    scopus 로고
    • A Ras-GTPaseactivating protein SH3-domain-binding protein
    • Parker F., F. Maurier, I. Delumeau, et al. (1996). A Ras-GTPaseactivating protein SH3-domain-binding protein. Mol. Cell. Biol. l16: 2561-2569.
    • (1996) Mol. Cell. Biol. L , vol.16 , pp. 2561-2569
    • Parker, F.1    Maurier, F.2    Delumeau, I.3
  • 23
    • 0344758983 scopus 로고    scopus 로고
    • Starting the protein synthesis machine: Eukaryotic translation initiation
    • Preiss, T., and Hentze, M. W. (2003). Starting the protein synthesis machine: Eukaryotic translation initiation. Bioessays 25: 1201-1211.
    • (2003) Bioessays , vol.25 , pp. 1201-1211
    • Preiss, T.1    Hentze, M.W.2
  • 24
    • 5044229348 scopus 로고    scopus 로고
    • Molecular mechanisms of translational control
    • Gebauer, F., and Hentze, M. W. (2004). Molecular mechanisms of translational control. Nat. Rev. Mol. Cell Biol. 5: 827-835.
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 827-835
    • Gebauer, F.1    Hentze, M.W.2
  • 25
    • 2342584183 scopus 로고    scopus 로고
    • EIF4E-from translation to transformation
    • Mamane, Y., Petroulakis, E., Rong, L., et al. (2004). eIF4E-from translation to transformation. Oncogene 23: 3172-3179.
    • (2004) Oncogene , vol.23 , pp. 3172-3179
    • Mamane, Y.1    Petroulakis, E.2    Rong, L.3
  • 26
    • 13444259647 scopus 로고    scopus 로고
    • Regulation of capdependent translation by eIF4E inhibitory proteins
    • Richter, J. D., and N. Sonenberg. (2005). Regulation of capdependent translation by eIF4E inhibitory proteins. Nature 433: 477-480.
    • (2005) Nature , vol.433 , pp. 477-480
    • Richter, J.D.1    Sonenberg, N.2
  • 27
    • 13144276292 scopus 로고    scopus 로고
    • Rasputin, more promiscuous than ever: A review of G3BP
    • Irvine, K., R. Stirling, D. Hume, and D. Kennedy. (2004). Rasputin, more promiscuous than ever: A review of G3BP. Int. J. Dev. Biol. 48: 1065-1077.
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 1065-1077
    • Irvine, K.1    Stirling, R.2    Hume, D.3    Kennedy, D.4
  • 28
    • 0034996465 scopus 로고    scopus 로고
    • Expression ofkeratins in normal, immortalized and malignant oral epithelia in organotypic culture
    • Hansson, A., B. K. Bloor, Y. Haig, et al. (2001). Expression ofkeratins in normal, immortalized and malignant oral epithelia in organotypic culture. Oral Oncol. 37: 419-430.
    • (2001) Oral Oncol. , vol.37 , pp. 419-430
    • Hansson, A.1    Bloor, B.K.2    Haig, Y.3
  • 29
    • 0038069525 scopus 로고    scopus 로고
    • Defining desmosomal plakophilin-3 interactions
    • Bonné, S., B. Gilbert, M. Hatzfeld, et al. (2003). Defining desmosomal plakophilin-3 interactions. J. Cell. Biol. 161: 403-416.
    • (2003) J. Cell. Biol. , vol.161 , pp. 403-416
    • Bonné, S.1    Gilbert, B.2    Hatzfeld, M.3
  • 30
    • 51949092571 scopus 로고    scopus 로고
    • Cleavage of desmoglein 3 can explain its depletion from keratinocytes in pemphigus vulgaris
    • Cirillo, N., G. Campisi, F. Gombos, et al. (2008). Cleavage of desmoglein 3 can explain its depletion from keratinocytes in pemphigus vulgaris. Exp. Dermatol. 17: 858-863.
    • (2008) Exp. Dermatol. , vol.17 , pp. 858-863
    • Cirillo, N.1    Campisi, G.2    Gombos, F.3
  • 31
    • 32644452893 scopus 로고    scopus 로고
    • A novel explanation for acantholysis in pemphigus vulgaris: The basal cell shrinkage hypothesis
    • Bystryn, J. C., and S. A. Grando. (2006). A novel explanation for acantholysis in pemphigus vulgaris: The basal cell shrinkage hypothesis. J. Am. Acad. Dermatol. 54: 513-516.
    • (2006) J. Am. Acad. Dermatol. , vol.54 , pp. 513-516
    • Bystryn, J.C.1    Grando, S.A.2
  • 32
    • 84856457013 scopus 로고    scopus 로고
    • Pemphigus autoimmunity: Hypotheses and realities
    • Grando, S. A. (2012). Pemphigus autoimmunity: Hypotheses and realities. Autoimmunity 45: 7-35.
    • (2012) Autoimmunity , vol.45 , pp. 7-35
    • Grando, S.A.1
  • 33
    • 84867095467 scopus 로고    scopus 로고
    • Specific immunoglobulin isotypes correlate with disease activity, morphology, duration and HLA association in Pemphigus vulgaris
    • Dhandha, M. M., K. Seiffert-Sinha, and A. A. Sinha. (2012). Specific immunoglobulin isotypes correlate with disease activity, morphology, duration and HLA association in Pemphigus vulgaris. Autoimmunity 45: 516-526.
    • (2012) Autoimmunity , vol.45 , pp. 516-526
    • Dhandha, M.M.1    Seiffert-Sinha, K.2    Sinha, A.A.3
  • 34
    • 84856504376 scopus 로고    scopus 로고
    • Constructing immunoprofiles to deconstruct disease complexity in pemphigus
    • Sinha, A. A. (2012). Constructing immunoprofiles to deconstruct disease complexity in pemphigus. Autoimmunity 45: 36-43.
    • (2012) Autoimmunity , vol.45 , pp. 36-43
    • Sinha, A.A.1
  • 35
    • 84875948406 scopus 로고    scopus 로고
    • Desmosomal adhesion and pemphigus vulgaris: The first half of the story
    • Cirillo, N., and B. A. Al-Jandan. (2013). Desmosomal adhesion and pemphigus vulgaris: The first half of the story. Cell Commun. Adhes. 20: 1-10.
    • (2013) Cell Commun. Adhes. , vol.20 , pp. 1-10
    • Cirillo, N.1    Al-Jandan, B.A.2
  • 36
    • 84858451814 scopus 로고    scopus 로고
    • Inhibition of FAK prevents blisterformation in the neonatal mouse model of pemphigus vulgaris
    • Gil, M. P., T. Modol, A. Espana, and M. J. López-Zabalza. (2012). Inhibition of FAK prevents blisterformation in the neonatal mouse model of pemphigus vulgaris. Exp. Dermatol. 21: 254-259.
    • (2012) Exp. Dermatol. , vol.21 , pp. 254-259
    • Gil, M.P.1    Modol, T.2    Espana, A.3    López-Zabalza, M.J.4
  • 37
    • 0035200869 scopus 로고    scopus 로고
    • Dynamic expression and nuclear accumulation of beta-cateninduring the development of hair follicle-derived structures
    • Ridanpaa, M., R. Fodde, and M. Kielman. (2001). Dynamic expression and nuclear accumulation of beta-cateninduring the development of hair follicle-derived structures. Mech. Dev. 109: 173-181.
    • (2001) Mech. Dev. , vol.109 , pp. 173-181
    • Ridanpaa, M.1    Fodde, R.2    Kielman, M.3
  • 38
    • 77952848685 scopus 로고    scopus 로고
    • Role of E-Cadherin in epithelial architecture maintenance
    • Izaguirre, M. F., D. Larrea, J. F. Adur, et al. (2010). Role of E-Cadherin in epithelial architecture maintenance. Cell. Commun. Adhes. 17: 1-12.
    • (2010) Cell. Commun. Adhes. , vol.17 , pp. 1-12
    • Izaguirre, M.F.1    Larrea, D.2    Adur, J.F.3
  • 39
    • 0042168696 scopus 로고    scopus 로고
    • Identification of genes differentially expressed in mouse mammary epithelium transformed by an activated beta-catenin
    • Renou, J. P., B. Bierie, K. Miyoshi, et al. (2003). Identification of genes differentially expressed in mouse mammary epithelium transformed by an activated beta-catenin. Oncogene 22: 4594-4610.
    • (2003) Oncogene , vol.22 , pp. 4594-4610
    • Renou, J.P.1    Bierie, B.2    Miyoshi, K.3


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