메뉴 건너뛰기




Volumn 164, Issue 2, 2011, Pages 336-343

Deregulation of PERK in the autoimmune disease pemphigus vulgaris occurs via IgG-independent mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; INITIATION FACTOR 2ALPHA; PROTEIN KINASE; PROTEIN KINASE R LIKE ENDOPLASMIC RETICULUM KINASE; UNCLASSIFIED DRUG;

EID: 79551488771     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2010.10084.x     Document Type: Article
Times cited : (15)

References (44)
  • 3
    • 47849103273 scopus 로고    scopus 로고
    • Bullous pemphigoid and pemphigus vulgaris - Incidence and mortality in the UK: Population based cohort study
    • Langan SM, Smeeth L, Hubbard R, et al. Bullous pemphigoid and pemphigus vulgaris-incidence and mortality in the UK: population based cohort study. BMJ 2008; 337: a180.
    • (2008) BMJ , vol.337
    • Langan, S.M.1    Smeeth, L.2    Hubbard, R.3
  • 4
    • 34548544117 scopus 로고    scopus 로고
    • Randomized controlled open-label trial of four treatment regimens for pemphigus vulgaris
    • Chams-Davatchi C, Esmaili N, Daneshpazhooh M, et al. Randomized controlled open-label trial of four treatment regimens for pemphigus vulgaris. J Am Acad Dermatol 2007; 57: 622-8.
    • (2007) J Am Acad Dermatol , vol.57 , pp. 622-628
    • Chams-Davatchi, C.1    Esmaili, N.2    Daneshpazhooh, M.3
  • 5
    • 0029923133 scopus 로고    scopus 로고
    • Influence of treatment on the clinical course of pemphigus vulgaris
    • Carson PJ, Hameed A, Ahmed AR,. Influence of treatment on the clinical course of pemphigus vulgaris. J Am Acad Dermatol 1996; 34: 645-52.
    • (1996) J Am Acad Dermatol , vol.34 , pp. 645-652
    • Carson, P.J.1    Hameed, A.2    Ahmed, A.R.3
  • 6
    • 0033911628 scopus 로고    scopus 로고
    • Patterns of remission in pemphigus vulgaris
    • Herbst A, Bystryn JC,. Patterns of remission in pemphigus vulgaris. J Am Acad Dermatol 2000; 42: 422-7.
    • (2000) J Am Acad Dermatol , vol.42 , pp. 422-427
    • Herbst, A.1    Bystryn, J.C.2
  • 7
    • 0029017682 scopus 로고
    • The treatment of pemphigus vulgaris. Experience with 48 patients seen over an 11-year period
    • Mourellou O, Chaidemenos GC, Koussidou T, Kapetis E,. The treatment of pemphigus vulgaris. Experience with 48 patients seen over an 11-year period. Br J Dermatol 1995; 133: 83-7.
    • (1995) Br J Dermatol , vol.133 , pp. 83-87
    • Mourellou, O.1    Chaidemenos, G.C.2    Koussidou, T.3    Kapetis, E.4
  • 8
    • 44449092953 scopus 로고    scopus 로고
    • The desmosome and pemphigus
    • Waschke J,. The desmosome and pemphigus. Histochem Cell Biol 2008; 130: 21-54.
    • (2008) Histochem Cell Biol , vol.130 , pp. 21-54
    • Waschke, J.1
  • 9
    • 34547113086 scopus 로고    scopus 로고
    • Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity
    • Yamamoto Y, Aoyama Y, Shu E, et al. Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity. J Biol Chem 2007; 282: 17866-76.
    • (2007) J Biol Chem , vol.282 , pp. 17866-17876
    • Yamamoto, Y.1    Aoyama, Y.2    Shu, E.3
  • 10
    • 33646592529 scopus 로고    scopus 로고
    • Serum from pemphigus vulgaris reduces desmoglein 3 half-life and perturbs its de novo assembly to desmosomal sites in cultured keratinocytes
    • Cirillo N, Femiano F, Gombos F, Lanza A,. Serum from pemphigus vulgaris reduces desmoglein 3 half-life and perturbs its de novo assembly to desmosomal sites in cultured keratinocytes. FEBS Lett 2006; 580: 3276-81.
    • (2006) FEBS Lett , vol.580 , pp. 3276-3281
    • Cirillo, N.1    Femiano, F.2    Gombos, F.3    Lanza, A.4
  • 11
    • 41849087707 scopus 로고    scopus 로고
    • At least three phosphorylation events induced by pemphigus vulgaris sera are pathogenically involved in keratinocyte acantholysis
    • Cirillo N, Lanza M, De Rosa A, et al. At least three phosphorylation events induced by pemphigus vulgaris sera are pathogenically involved in keratinocyte acantholysis. Int J Immunopathol Pharmacol 2008; 21: 189-95.
    • (2008) Int J Immunopathol Pharmacol , vol.21 , pp. 189-195
    • Cirillo, N.1    Lanza, M.2    De Rosa, A.3
  • 12
    • 0347087440 scopus 로고    scopus 로고
    • Pemphigus vulgaris IgG and methylprednisolone exhibit reciprocal effects on keratinocytes
    • Nguyen VT, Arredondo J, Chernyavsky AI, et al. Pemphigus vulgaris IgG and methylprednisolone exhibit reciprocal effects on keratinocytes. J Biol Chem 2004; 279: 2135-46.
    • (2004) J Biol Chem , vol.279 , pp. 2135-2146
    • Nguyen, V.T.1    Arredondo, J.2    Chernyavsky, A.I.3
  • 13
    • 77950590873 scopus 로고    scopus 로고
    • P38MAPK signaling and desmoglein-3 internalization are linked events in pemphigus acantholysis
    • Jolly PS, Berkowitz P, Bektas M, et al. p38MAPK signaling and desmoglein-3 internalization are linked events in pemphigus acantholysis. J Biol Chem 2010; 285: 8936-41.
    • (2010) J Biol Chem , vol.285 , pp. 8936-8941
    • Jolly, P.S.1    Berkowitz, P.2    Bektas, M.3
  • 14
    • 34250354415 scopus 로고    scopus 로고
    • Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: Characterization of novel signaling pathways downstream of pemphigus vulgaris antigens
    • Chernyavsky AI, Arredondo J, Kitajima Y, et al. Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: characterization of novel signaling pathways downstream of pemphigus vulgaris antigens. J Biol Chem 2007; 282: 13804-12.
    • (2007) J Biol Chem , vol.282 , pp. 13804-13812
    • Chernyavsky, A.I.1    Arredondo, J.2    Kitajima, Y.3
  • 15
    • 34547950565 scopus 로고    scopus 로고
    • If pemphigus vulgaris IgG are the cause of acantholysis, new IgG-independent mechanisms are the concause
    • Cirillo N, Lanza M, Femiano F, et al. If pemphigus vulgaris IgG are the cause of acantholysis, new IgG-independent mechanisms are the concause. J Cell Physiol 2007; 212: 563-7.
    • (2007) J Cell Physiol , vol.212 , pp. 563-567
    • Cirillo, N.1    Lanza, M.2    Femiano, F.3
  • 16
    • 69149094112 scopus 로고    scopus 로고
    • Apoptolysis: A novel mechanism of skin blistering in pemphigus vulgaris linking the apoptotic pathways to basal cell shrinkage and suprabasal acantholysis
    • Grando SA, Bystryn JC, Chernyavsky AI, et al. Apoptolysis: a novel mechanism of skin blistering in pemphigus vulgaris linking the apoptotic pathways to basal cell shrinkage and suprabasal acantholysis. Exp Dermatol 2009; 18: 764-70.
    • (2009) Exp Dermatol , vol.18 , pp. 764-770
    • Grando, S.A.1    Bystryn, J.C.2    Chernyavsky, A.I.3
  • 17
    • 41249092968 scopus 로고    scopus 로고
    • Differential coupling of M1 muscarinic and alpha7 nicotinic receptors to inhibition of pemphigus acantholysis
    • Chernyavsky AI, Arredondo J, Piser T, et al. Differential coupling of M1 muscarinic and alpha7 nicotinic receptors to inhibition of pemphigus acantholysis. J Biol Chem 2008; 283: 3401-8.
    • (2008) J Biol Chem , vol.283 , pp. 3401-3408
    • Chernyavsky, A.I.1    Arredondo, J.2    Piser, T.3
  • 18
    • 43749105814 scopus 로고    scopus 로고
    • Evidence of key role of Cdk2 overexpression in pemphigus vulgaris
    • Lanza A, Cirillo N, Rossiello R, et al. Evidence of key role of Cdk2 overexpression in pemphigus vulgaris. J Biol Chem 2008; 283: 8736-45.
    • (2008) J Biol Chem , vol.283 , pp. 8736-8745
    • Lanza, A.1    Cirillo, N.2    Rossiello, R.3
  • 19
    • 33748069469 scopus 로고    scopus 로고
    • P38MAPK inhibition prevents disease in pemphigus vulgaris mice
    • Berkowitz P, Hu P, Warren S, et al. p38MAPK inhibition prevents disease in pemphigus vulgaris mice. Proc Natl Acad Sci USA 2006; 103: 12855-60.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12855-12860
    • Berkowitz, P.1    Hu, P.2    Warren, S.3
  • 20
    • 0023852747 scopus 로고
    • Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line
    • Boukamp P, Petrussevska RT, Breitkreutz D, et al. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 1988; 106: 761-71.
    • (1988) J Cell Biol , vol.106 , pp. 761-771
    • Boukamp, P.1    Petrussevska, R.T.2    Breitkreutz, D.3
  • 21
    • 0032526941 scopus 로고    scopus 로고
    • Tyrosine phosphorylation and Src-family kinases control keratinocyte cell-cell adhesion
    • Calautti E, Cabodi S, Stein PL, et al. Tyrosine phosphorylation and Src-family kinases control keratinocyte cell-cell adhesion. J Cell Biol 1998; 141: 1449-65.
    • (1998) J Cell Biol , vol.141 , pp. 1449-1465
    • Calautti, E.1    Cabodi, S.2    Stein, P.L.3
  • 22
    • 77449142413 scopus 로고    scopus 로고
    • Induction of hyper-adhesion attenuates autoimmune-induced keratinocyte cell-cell detachment and processing of adhesion molecules via mechanisms that involve PKC
    • Cirillo N, Lanza A, Prime SS,. Induction of hyper-adhesion attenuates autoimmune-induced keratinocyte cell-cell detachment and processing of adhesion molecules via mechanisms that involve PKC. Exp Cell Res 2010; 316: 580-92.
    • (2010) Exp Cell Res , vol.316 , pp. 580-592
    • Cirillo, N.1    Lanza, A.2    Prime, S.S.3
  • 23
    • 0037238398 scopus 로고    scopus 로고
    • Fas ligand in pemphigus sera induces keratinocyte apoptosis through the activation of caspase-8
    • Puviani M, Marconi A, Cozzani E, Pincelli C,. Fas ligand in pemphigus sera induces keratinocyte apoptosis through the activation of caspase-8. J Invest Dermatol 2003; 120: 164-7.
    • (2003) J Invest Dermatol , vol.120 , pp. 164-167
    • Puviani, M.1    Marconi, A.2    Cozzani, E.3    Pincelli, C.4
  • 24
    • 0033303154 scopus 로고    scopus 로고
    • Anti-intercellular substance antibody log titres are correlated with serum concentrations of interleukin-6, interleukin-15 and tumor necrosis factor-alpha in patients with pemphigus vulgaris relationships with peripheral blood neutrophil counts, disease severity and duration and patients' age
    • Ameglio F, D'Auria L, Cordiali-Fei P, et al. Anti-intercellular substance antibody log titres are correlated with serum concentrations of interleukin-6, interleukin-15 and tumor necrosis factor-alpha in patients with pemphigus vulgaris relationships with peripheral blood neutrophil counts, disease severity and duration and patients' age. J Biol Regul Homeost Agents 1999; 13: 220-4.
    • (1999) J Biol Regul Homeost Agents , vol.13 , pp. 220-224
    • Ameglio, F.1    D'Auria, L.2    Cordiali-Fei, P.3
  • 25
    • 0034904154 scopus 로고    scopus 로고
    • Pemphigus vulgaris: The role of IL-1 and IL-1 receptor antagonist in pathogenesis and effects of intravenous immunoglobulin on their production
    • Bhol KC, Desai A, Kumari S, et al. Pemphigus vulgaris: the role of IL-1 and IL-1 receptor antagonist in pathogenesis and effects of intravenous immunoglobulin on their production. Clin Immunol 2001; 100: 172-80.
    • (2001) Clin Immunol , vol.100 , pp. 172-180
    • Bhol, K.C.1    Desai, A.2    Kumari, S.3
  • 26
    • 48449096748 scopus 로고    scopus 로고
    • Serum concentration of interleukin-6 is increased both in active and remission stages of pemphigus vulgaris
    • Narbutt J, Lukamowicz J, Bogaczewicz J, et al. Serum concentration of interleukin-6 is increased both in active and remission stages of pemphigus vulgaris. Mediators Inflamm 2008; 2008: 875394.
    • (2008) Mediators Inflamm , vol.2008 , pp. 875394
    • Narbutt, J.1    Lukamowicz, J.2    Bogaczewicz, J.3
  • 27
    • 33646425321 scopus 로고    scopus 로고
    • Evidence for the participation of nitric oxide in pemphigus
    • Siebra MX, Santos MA, Almeida TL, et al. Evidence for the participation of nitric oxide in pemphigus. Braz J Med Biol Res 2006; 39: 671-5.
    • (2006) Braz J Med Biol Res , vol.39 , pp. 671-675
    • Siebra, M.X.1    Santos, M.A.2    Almeida, T.L.3
  • 29
    • 0027089866 scopus 로고
    • Decompensation in proteinase-inhibitor system and application of proteinase inhibitors in pemphigus and pemphigoid
    • Grando SA,. Decompensation in proteinase-inhibitor system and application of proteinase inhibitors in pemphigus and pemphigoid. J Dermatol Sci 1992; 4: 95-7.
    • (1992) J Dermatol Sci , vol.4 , pp. 95-97
    • Grando, S.A.1
  • 30
    • 34248232439 scopus 로고    scopus 로고
    • Defining the involvement of proteinases in pemphigus vulgaris: Evidence of matrix metalloproteinase-9 overexpression in experimental models of disease
    • Cirillo N, Lanza M, Rossiello L, et al. Defining the involvement of proteinases in pemphigus vulgaris: evidence of matrix metalloproteinase-9 overexpression in experimental models of disease. J Cell Physiol 2007; 212: 36-41.
    • (2007) J Cell Physiol , vol.212 , pp. 36-41
    • Cirillo, N.1    Lanza, M.2    Rossiello, L.3
  • 31
    • 22244446505 scopus 로고    scopus 로고
    • The mammalian unfolded protein response
    • Schröder M, Kaufman RJ,. The mammalian unfolded protein response. Annu Rev Biochem 2005; 74: 739-89.
    • (2005) Annu Rev Biochem , vol.74 , pp. 739-789
    • Schröder, M.1    Kaufman, R.J.2
  • 32
    • 33645154135 scopus 로고    scopus 로고
    • Cellular response to endoplasmic reticulum stress: A matter of life or death
    • Boyce M, Yuan J,. Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 2006; 13: 363-73.
    • (2006) Cell Death Differ , vol.13 , pp. 363-373
    • Boyce, M.1    Yuan, J.2
  • 33
    • 56849113081 scopus 로고    scopus 로고
    • Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress
    • Chami M, Oulès B, Szabadkai G, et al. Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress. Mol Cell 2008; 32: 641-51.
    • (2008) Mol Cell , vol.32 , pp. 641-651
    • Chami, M.1    Oulès, B.2    Szabadkai, G.3
  • 34
    • 77950346841 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47
    • Bourougaa K, Naski N, Boularan C, et al. Endoplasmic reticulum stress induces G2 cell-cycle arrest via mRNA translation of the p53 isoform p53/47. Mol Cell 2010; 38: 78-88.
    • (2010) Mol Cell , vol.38 , pp. 78-88
    • Bourougaa, K.1    Naski, N.2    Boularan, C.3
  • 35
    • 74249099955 scopus 로고    scopus 로고
    • N-acetyl cysteine and penicillamine induce apoptosis via the ER stress response-signaling pathway
    • Guan D, Xu Y, Yang M, et al. N-acetyl cysteine and penicillamine induce apoptosis via the ER stress response-signaling pathway. Mol Carcinog 2010; 49: 68-74.
    • (2010) Mol Carcinog , vol.49 , pp. 68-74
    • Guan, D.1    Xu, Y.2    Yang, M.3
  • 36
    • 77953232252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2alpha in caspase-3/7-deficient cells
    • Kim KW, Moretti L, Mitchell LR, et al. Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2alpha in caspase-3/7-deficient cells. Oncogene 2010; 29: 3241-51.
    • (2010) Oncogene , vol.29 , pp. 3241-3251
    • Kim, K.W.1    Moretti, L.2    Mitchell, L.R.3
  • 37
    • 53549119055 scopus 로고    scopus 로고
    • Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation
    • Park MA, Zhang G, Martin AP, et al. Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. Cancer Biol Ther 2008; 7: 1648-62.
    • (2008) Cancer Biol Ther , vol.7 , pp. 1648-1662
    • Park, M.A.1    Zhang, G.2    Martin, A.P.3
  • 38
    • 77950472606 scopus 로고    scopus 로고
    • Antimitochondrial autoantibodies in pemphigus vulgaris: A missing link in disease pathophysiology
    • Marchenko S, Chernyavsky AI, Arredondo J, et al. Antimitochondrial autoantibodies in pemphigus vulgaris: a missing link in disease pathophysiology. J Biol Chem 2010; 285: 3695-704.
    • (2010) J Biol Chem , vol.285 , pp. 3695-3704
    • Marchenko, S.1    Chernyavsky, A.I.2    Arredondo, J.3
  • 39
    • 69249132997 scopus 로고    scopus 로고
    • Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress - But not nitric oxide-mediated apoptosis in INS-1E cells
    • Tonnesen MF, Grunnet LG, Friberg J, et al. Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress-but not nitric oxide-mediated apoptosis in INS-1E cells. Endocrinology 2009; 150: 4094-103.
    • (2009) Endocrinology , vol.150 , pp. 4094-4103
    • Tonnesen, M.F.1    Grunnet, L.G.2    Friberg, J.3
  • 40
    • 34548845571 scopus 로고    scopus 로고
    • Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes
    • Okunade GW, Miller ML, Azhar M, et al. Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes. J Biol Chem 2007; 282: 26517-27.
    • (2007) J Biol Chem , vol.282 , pp. 26517-26527
    • Okunade, G.W.1    Miller, M.L.2    Azhar, M.3
  • 41
    • 38549126756 scopus 로고    scopus 로고
    • Darier's disease: A calcium-signaling perspective
    • Pani B, Singh BB,. Darier's disease: a calcium-signaling perspective. Cell Mol Life Sci 2008; 65: 205-11.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 205-211
    • Pani, B.1    Singh, B.B.2
  • 43
    • 70349878700 scopus 로고    scopus 로고
    • Desmosomal interactome in keratinocytes: A systems biology approach leading to an understanding of the pathogenesis of skin disease
    • Cirillo N, Prime SS,. Desmosomal interactome in keratinocytes: a systems biology approach leading to an understanding of the pathogenesis of skin disease. Cell Mol Life Sci 2009; 66: 3517-33.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 3517-3533
    • Cirillo, N.1    Prime, S.S.2
  • 44
    • 0037032835 scopus 로고    scopus 로고
    • The protein kinase complement of the human genome
    • Manning G, Whyte DB, Martinez R, et al. The protein kinase complement of the human genome. Science 2002; 298: 1912-34.
    • (2002) Science , vol.298 , pp. 1912-1934
    • Manning, G.1    Whyte, D.B.2    Martinez, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.