A novel polysaccharide from Ganoderma atrum exerts antitumor activity by activating mitochondria-mediated apoptotic pathway and boosting the immune system

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 7, 2014, Pages 1581-1589

  Zhang, Shenshen ^a   Nie, Shaoping ^a   Huang, Danfei ^a   Feng, Yanling ^a   Xie, Mingyong ^a  

^a NANCHANG UNIVERSITY   (China)

Author keywords

antitumor; apoptosis; CT26; Ganoderma atrum polysaccharide; immunomodulatory

Indexed keywords

CELL DEATH; CELL MEMBRANES; CELL PROLIFERATION; CHEMICAL ACTIVATION; IMMUNE SYSTEM; MITOCHONDRIA; TUMORS;

ANTI-TUMOR ACTIVITIES; ANTI-TUMORS; CT26; GANODERMA; IMMUNOMODULATORY; LYMPHOCYTE PROLIFERATION; MITOCHONDRIAL CYTOCHROME C; MITOCHONDRIAL MEMBRANE POTENTIAL;

BIOTECHNOLOGY;

FUNGI; GANODERMA; MUS;

ANTINEOPLASTIC AGENT; CYTOCHROME C; CYTOKINE; POLYSACCHARIDE; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; GANODERMA; GENETICS; HUMAN; IMMUNE SYSTEM; IMMUNOLOGY; LYMPHOCYTE; MALE; METABOLISM; MITOCHONDRION; NEOPLASM; PATHOPHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOCHROMES C; CYTOKINES; GANODERMA; HUMANS; IMMUNE SYSTEM; LYMPHOCYTES; MALE; MICE, INBRED BALB C; MITOCHONDRIA; NEOPLASMS; POLYSACCHARIDES; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84894437379     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf4053012     Document Type: Article

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