TAB1: A target of triptolide in macrophages

Chemistry and Biology

Volumn 21, Issue 2, 2014, Pages 246-256

  Lu, Yan ^a   Zhang, Ya ^a   Li, Long ^a   Feng, Xiujing ^a   Ding, Sen ^a   Zheng, Wei ^a   Li, Jianxin ^a   Shen, Pingping ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CYTOKINES; DITERPENES; EPOXY COMPOUNDS; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PHENANTHRENES; PROTEIN BINDING; RECOMBINANT PROTEINS; TRIPTERYGIUM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84894411399     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.12.009     Document Type: Article

References (56)

1. X. Bao, J. Cui, Y. Wu, X. Han, C. Gao, Z. Hua, and P. Shen The roles of endogenous reactive oxygen species and nitric oxide in triptolide-induced apoptotic cell death in macrophages J. Mol. Med. 85 2007 85 98
2. D. Buglio, S. Palakurthi, K. Byth, F. Vega, D. Toader, J. Saeh, S.S. Neelapu, and A. Younes Essential role of TAK1 in regulating mantle cell lymphoma survival Blood 120 2012 347 355
3. B.J. Chen Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F Leuk. Lymphoma 42 2001 253 265
4. Y.W. Chen, G.J. Lin, W.T. Chia, C.K. Lin, Y.P. Chuang, and H.K. Sytwu Triptolide exerts anti-tumor effect on oral cancer and KB cells in vitro and in vivo Oral Oncol. 45 2009 562 568
5. T. Chen, D. Ozel, Y. Qiao, F. Harbinski, L. Chen, S. Denoyelle, X. He, N. Zvereva, J.G. Supko, and M. Chorev et al. Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target Nat. Chem. Biol. 7 2011 610 616
6. T.W. Corson, H. Cavga, N. Aberle, and C.M. Crews Triptolide directly inhibits dCTP pyrophosphatase ChemBioChem 12 2011 1767 1773
7. G. Courties, V. Seiffart, V. Escriou, D. Scherman, A. Hoffmann, C. Jorgensen, G. Gross, and F. Apparailly RNAi-based therapy to target TAK1 in rheumatoid arthritis Hum. Gene Ther. 19 2008 1169-1169
8. J. Cox, and M. Mann MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification Nat. Biotechnol. 26 2008 1367 1372
9. N. Fujiwara, and K. Kobayashi Macrophages in inflammation Curr. Drug Targets Inflamm. Allergy 4 2005 281 286
10. B.X. Ge, H. Gram, F. Di Padova, B. Huang, L. New, R.J. Ulevitch, Y. Luo, and J.H. Han MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha Science 295 2002 1291 1294
11. M. Gersch, J. Kreuzer, and S.A. Sieber Electrophilic natural products and their biological targets Nat. Prod. Rep. 29 2012 659 682
12. M. Guha, and N. Mackman LPS induction of gene expression in human monocytes Cell. Signal. 13 2001 85 94
13. M. Hammer, J. Mages, H. Dietrich, A. Servatius, N. Howells, A.C.B. Cato, and R. Lang Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock J. Exp. Med. 203 2006 15 20
14. J.K. He, S.D. Yu, H.J. Zhu, J.C. Wu, and Z.H. Qin Triptolide inhibits NF-kappaB activation and reduces injury of donor lung induced by ischemia/reperfusion Acta Pharmacol. Sin. 28 2007 1919 1923
15. E. Heiss, C. Herhaus, K. Klimo, H. Bartsch, and C. Gerhäuser Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms J. Biol. Chem. 276 2001 32008 32015
16. Y.J. Hu, Y. Liu, J.B. Wang, X.H. Xiao, and S.S. Qu Study of the interaction between monoammonium glycyrrhizinate and bovine serum albumin J. Pharm. Biomed. Anal. 36 2004 915 919
17. K. Ito, S. Lim, G. Caramori, B. Cosio, K.F. Chung, I.M. Adcock, and P.J. Barnes A molecular mechanism of action of theophylline: induction of histone deacetylase activity to decrease inflammatory gene expression Proc. Natl. Acad. Sci. USA 99 2002 8921 8926
18. Y.J. Kang, J. Chen, M. Otsuka, J. Mols, S. Ren, Y. Wang, and J. Han Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation J. Immunol. 180 2008 5075 5082
19. S.I. Kim, J.H. Kwak, H.J. Na, J.K. Kim, Y. Ding, and M.E. Choi Transforming growth factor-beta (TGF-beta1) activates TAK1 via TAB1-mediated autophosphorylation, independent of TGF-beta receptor kinase activity in mesangial cells J. Biol. Chem. 284 2009 22285 22296
20. K. Kishimoto, K. Matsumoto, and J. Ninomiya-Tsuji TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop J. Biol. Chem. 275 2000 7359 7364
21. T.M. Kiviharju, P.S. Lecane, R.G. Sellers, and D.M. Peehl Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells Clin. Cancer Res. 8 2002 2666 2674
22. J. Lee, L. Mira-Arbibe, and R.J. Ulevitch TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide J. Leukoc. Biol. 68 2000 909 915
23. S.J. Leuenroth, and C.M. Crews Studies on calcium dependence reveal multiple modes of action for triptolide Chem. Biol. 12 2005 1259 1268
24. S.J. Leuenroth, D. Okuhara, J.D. Shotwell, G.S. Markowitz, Z.H. Yu, S. Somlo, and C.M. Crews Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease Proc. Natl. Acad. Sci. USA 104 2007 4389 4394
25. B.P. Leung, N. Sattar, A. Crilly, M. Prach, D.W. McCarey, H. Payne, R. Madhok, C. Campbell, J.A. Gracie, F.Y. Liew, and I.B. McInnes A novel anti-inflammatory role for simvastatin in inflammatory arthritis J. Immunol. 170 2003 1524 1530
26. Q. Liu Triptolide and its expanding multiple pharmacological functions Int. Immunopharmacol. 11 2011 377 383
27. J. Liu, M. Shen, Z. Yue, Z. Yang, M. Wang, C. Li, C. Xin, Y. Wang, Q. Mei, and Z. Wang Triptolide inhibits colon-rectal cancer cells proliferation by induction of G1 phase arrest through upregulation of p21 Phytomedicine 19 2012 756 762
28. Y. Lu, X. Bao, T. Sun, J. Xu, W. Zheng, and P. Shen Triptolide attenuate the oxidative stress induced by LPS/D-GalN in mice J. Cell. Biochem. 113 2012 1022 1033
29. J. Ma, M. Dey, H. Yang, A. Poulev, R. Pouleva, R. Dorn, P.E. Lipsky, E.J. Kennelly, and I. Raskin Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii Phytochemistry 68 2007 1172 1178
30. S.E. Martin, Y. Pommier, and N.J. Caplen RNAi screening identifies TAK1 as a potential target for the enhanced efficacy of traditional cytotoxic agents in breast cancer cells Mol. Cancer Ther. 6 2007 3331s-3331s
31. C. McCallum, S. Kwon, P. Leavitt, D.M. Shen, W. Liu, and A. Gurnett Triptolide binds covalently to a 90 kDa nuclear protein. Role of epoxides in binding and activity Immunobiology 212 2007 549 556
32. D. Melisi, Q. Xia, J.L. Abbruzzese, and P.J. Chiao TGF-beta-activated kinase 1 (TAK1) is an in vivo druggable target for reverting pancreatic cancer chemoresistance JOP 14 Suppl 5 2009 87
33. C. Nathan, and A. Ding Nonresolving inflammation Cell 140 2010 871 882
34. J. Nie, M. Zhou, C. Lü, X. Hu, B. Wan, B. Yang, and Y. Li Effects of triptolide on the synaptophysin expression of hippocampal neurons in the AD cellular model Int. Immunopharmacol. 13 2012 175 180
35. J. Ninomiya-Tsuji, K. Kishimoto, A. Hiyama, J. Inoue, Z.D. Cao, and K. Matsumoto The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway Nature 398 1999 252 256
36. Y. Nishiya, K. Shibata, S. Saito, K. Yano, C. Oneyama, H. Nakano, and S.V. Sharma Drug-target identification from total cellular lysate by drug-induced conformational changes Anal. Biochem. 385 2009 314 320
37. K. Ono, T. Ohtomo, S. Sato, Y. Sugamata, M. Suzuki, N. Hisamoto, J. Ninomiya-Tsuji, M. Tsuchiya, and K. Matsumoto An evolutionarily conserved motif in the TAB1 C-terminal region is necessary for interaction with and activation of TAK1 MAPKKK J. Biol. Chem. 276 2001 24396 24400
38. V. Premkumar, M. Dey, R. Dorn, and I. Raskin MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages BMC Chem. Biol. 10 2010 3
39. M. Raman, and M.H. Cobb MAP kinase modules: many roads home Curr. Biol. 13 2003 R886 R888
40. H. Sakurai, H. Miyoshi, J. Mizukami, and T. Sugita Phosphorylation- dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1 FEBS Lett. 474 2000 141 145
41. M. Sarkar, S.S. Paul, and K.K. Mukherjea Interaction of bovine serum albumin with a psychotropic drug alprazolam: Physicochemical, photophysical and molecular docking studies J. Lumin. 142 2013 220 230
42. H. Shibuya, K. Yamaguchi, K. Shirakabe, A. Tonegawa, Y. Gotoh, N. Ueno, K. Irie, E. Nishida, and K. Matsumoto TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction Science 272 1996 1179 1182
43. M.S. Shin, P. Shinghirunnusorn, Y. Sugishima, M. Nishimura, S. Suzuki, K. Koizumi, I. Saiki, and H. Sakurai Cross interference with TNF-alpha-induced TAK1 activation via EGFR-mediated p38 phosphorylation of TAK1-binding protein 1 Biochim. Biophys. Acta 1793 2009 1156 1164
44. M. Suzuki, I. Tachibana, Y. Takeda, P. He, S. Minami, T. Iwasaki, H. Kida, S. Goya, T. Kijima, and M. Yoshida et al. Tetraspanin CD9 negatively regulates lipopolysaccharide-induced macrophage activation and lung inflammation J. Immunol. 182 2009 6485 6493
45. D.V. Titov, B. Gilman, Q.L. He, S. Bhat, W.K. Low, Y.J. Dang, M. Smeaton, A.L. Demain, P.S. Miller, and J.F. Kugel et al. XPB, a subunit of TFIIH, is a target of the natural product triptolide Nat. Chem. Biol. 7 2011 182 188
46. S.H. Tsai, S.Y. Lin-Shiau, and J.K. Lin Suppression of nitric oxide synthase and the down-regulation of the activation of NFkappaB in macrophages by resveratrol Br. J. Pharmacol. 126 1999 673 680
47. B. Vera, A.D. Rodríguez, and J.J. La Clair Aplysqualenol A binds to the light chain of dynein type 1 (DYNLL1) Angew. Chem. Int. Ed. Engl. 50 2011 8134 8138
48. R. Wadgaonkar, J.W. Pierce, K. Somnay, R.L. Damico, M.T. Crow, T. Collins, and J.G.N. Garcia Regulation of c-Jun N-terminal kinase and p38 kinase pathways in endothelial cells Am. J. Respir. Cell Mol. Biol. 31 2004 423 431
49. T.C. Walther, and M. Mann Mass spectrometry-based proteomics in cell biology J. Cell Biol. 190 2010 491 500
50. W.F. Wang, G.S. Zhou, M.C.T. Hu, Z.B. Yao, and T.H. Tan Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor beta (TGF-beta)-activated kinase (TAK1), a kinase mediator of TGF beta signal transduction J. Biol. Chem. 272 1997 22771 22775
51. J.H. Wolf, and J. Korf 4-Bromomethyl-7-methoxycoumarin and analogues as derivatization agents for high-performance liquid chromatography determinations: a review J. Pharm. Biomed. Anal. 10 1992 99 107
52. Y. Wu, J. Cui, X. Bao, S. Chan, D.O. Young, D. Liu, and P. Shen Triptolide attenuates oxidative stress, NF-kappaB activation and multiple cytokine gene expression in murine peritoneal macrophage Int. J. Mol. Med. 17 2006 141 150
53. K. Yamaguchi, K. Shirakabe, H. Shibuya, K. Irie, I. Oishi, N. Ueno, T. Taniguchi, E. Nishida, and K. Matsumoto Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction Science 270 1995 2008 2011
54. Y. Zhang, and X. Ma Triptolide inhibits IL-12/IL-23 expression in APCs via CCAAT/enhancer-binding protein alpha J. Immunol. 184 2010 3866 3877
55. G. Zhao, L.T. Vaszar, D. Qiu, L. Shi, and P.N. Kao Anti-inflammatory effects of triptolide in human bronchial epithelial cells Am. J. Physiol. Lung Cell. Mol. Physiol. 279 2000 L958 L966
56. R. Zhou, S.X. Zheng, W. Tang, P.L. He, X.Y. Li, Y.F. Yang, Y.C. Li, J.G. Geng, and J.P. Zuo Inhibition of inducible nitric-oxide synthase expression by (5R)-5-hydroxytriptolide in interferon-gamma- and bacterial lipopolysaccharide- stimulated macrophages J. Pharmacol. Exp. Ther. 316 2006 121 128