Interplay between conformational selection and induced fit in multidomain protein-ligand binding probed by paramagnetic relaxation enhancement

Biophysical Chemistry

Volumn 186, Issue , 2014, Pages 3-12

  Clore, G Marius ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Calmodulin; Conformational selection; Induced fit; Maltose binding protein; Paramagnetic relaxation enhancement; Sparsely populated transient state

Indexed keywords

CALMODULIN; LIGAND; MALTOSE BINDING PROTEIN; PROTEIN;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

CALMODULIN; CONFORMATIONAL SELECTION; INDUCED FIT; MALTOSE BINDING PROTEIN; PARAMAGNETIC RELAXATION ENHANCEMENT; SPARSELY-POPULATED TRANSIENT STATE;

ANIMALS; CALMODULIN; HUMANS; LIGANDS; MALTOSE-BINDING PROTEINS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84894280807     PISSN: 03014622     EISSN: 18734200     Source Type: Journal    
DOI: 10.1016/j.bpc.2013.08.006     Document Type: Review

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