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Volumn 7, Issue 313, 2014, Pages

Tumor-induced STAT3 signaling in myeloid cells impairs dendritic cell generation by decreasing PKCβII abundance

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BREAST NEOPLASMS; DENDRITIC CELLS; FEMALE; HUMANS; K562 CELLS; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, INBRED BALB C; MYELOID PROGENITOR CELLS; NEOPLASM PROTEINS; PROTEIN KINASE C BETA; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84894274842     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2004656     Document Type: Article
Times cited : (44)

References (57)
  • 2
    • 0035139983 scopus 로고    scopus 로고
    • Danger signals: SOS to the immune system
    • S. Gallucci, P. Matzinger, Danger signals: SOS to the immune system. Curr. Opin. Immunol. 13, 114-119 (2001).
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 114-119
    • Gallucci, S.1    Matzinger, P.2
  • 4
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumour-induced dendriticcell defects
    • D. Gabrilovich, Mechanisms and functional significance of tumour-induced dendriticcell defects. Nat. Rev. Immunol. 4, 941-952 (2004).
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 6
    • 14844362003 scopus 로고    scopus 로고
    • Δ-9-Tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response
    • R. J. McKallip, M. Nagarkatti, P. S. Nagarkatti, Δ-9- Tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. J. Immunol. 174, 3281-3289 (2005).
    • (2005) J. Immunol. , vol.174 , pp. 3281-3289
    • McKallip, R.J.1    Nagarkatti, M.2    Nagarkatti, P.S.3
  • 11
    • 79955723632 scopus 로고    scopus 로고
    • Myeloid derived suppressor cells in human diseases
    • T. F. Greten, M. P. Manns, F. Korangy, Myeloid derived suppressor cells in human diseases. Int. Immunopharmacol. 11, 802-807 (2011).
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 802-807
    • Greten, T.F.1    Manns, M.P.2    Korangy, F.3
  • 13
    • 81155131681 scopus 로고    scopus 로고
    • Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism
    • J. D. Waight, Q. Hu, A. Miller, S. Liu, S. I. Abrams, Tumor-derived G-CSF facilitates neoplastic growth through a granulocytic myeloid-derived suppressor cell-dependent mechanism. PLOS One 6, e27690 (2011).
    • (2011) PLOS One , vol.6
    • Waight, J.D.1    Hu, Q.2    Miller, A.3    Liu, S.4    Abrams, S.I.5
  • 14
    • 21544473172 scopus 로고    scopus 로고
    • Targeting STAT3 affects melanoma on multiple fronts
    • M. Kortylewski, R. Jove, H. Yu, Targeting STAT3 affects melanoma on multiple fronts. Cancer Metastasis Rev. 24, 315-327 (2005).
    • (2005) Cancer Metastasis Rev. , vol.24 , pp. 315-327
    • Kortylewski, M.1    Jove, R.2    Yu, H.3
  • 17
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • D. I. Gabrilovich, S. Nagaraj, Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9, 162-174 (2009).
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 20
    • 0031786125 scopus 로고    scopus 로고
    • The sevenfold way of PKC regulation
    • W. S. Liu, C. A. Heckman, The sevenfold way of PKC regulation. Cell. Signal. 10, 529- 542 (1998).
    • (1998) Cell. Signal. , vol.10 , pp. 529-542
    • Liu, W.S.1    Heckman, C.A.2
  • 21
    • 34948840876 scopus 로고    scopus 로고
    • + monocyte differentiation towards macrophages and dendritic cells, respectively
    • + monocyte differentiation towards macrophages and dendritic cells, respectively. J. Cell. Biochem. 102, 429-441 (2007).
    • (2007) J. Cell. Biochem. , vol.102 , pp. 429-441
    • Lin, Y.F.1    Lee, H.M.2    Leu, S.J.3    Tsai, Y.H.4
  • 22
    • 0024448673 scopus 로고
    • Differential responsiveness to phorbol esters correlates with differential expression of protein kinase C in KG-1 and KG-1a human myeloid leukemia cells
    • W. C. Hooper, R. T. Abraham, C. L. Ashendel, G. E. Woloschak, Differential responsiveness to phorbol esters correlates with differential expression of protein kinase C in KG-1 and KG-1a human myeloid leukemia cells. Biochim. Biophys. Acta 1013, 47-54 (1989).
    • (1989) Biochim. Biophys. Acta , vol.1013 , pp. 47-54
    • Hooper, W.C.1    Abraham, R.T.2    Ashendel, C.L.3    Woloschak, G.E.4
  • 26
    • 0027240631 scopus 로고
    • Expression of rel B transcripts during lymphoid organ development: Specific expression in dendritic antigen-presenting cells
    • D. Carrasco, R. P. Ryseck, R. Bravo, Expression of rel B transcripts during lymphoid organ development: Specific expression in dendritic antigen-presenting cells. Development 118, 1221-1231 (1993).
    • (1993) Development , vol.118 , pp. 1221-1231
    • Carrasco, D.1    Ryseck, R.P.2    Bravo, R.3
  • 28
    • 17844375379 scopus 로고    scopus 로고
    • Critical roles of Raf/MEK/ ERK and PI3K/AKT signaling and inactivation of p38 MAP kinase in the differentiation and survival of monocyte-derived immature dendritic cells
    • J. Xie, J. Qian, J. Yang, S. Wang, M. E. Freeman III, Q. Yi, Critical roles of Raf/MEK/ ERK and PI3K/AKT signaling and inactivation of p38 MAP kinase in the differentiation and survival of monocyte-derived immature dendritic cells. Exp. Hematol. 33, 564-572 (2005).
    • (2005) Exp. Hematol. , vol.33 , pp. 564-572
    • Xie, J.1    Qian, J.2    Yang, J.3    Wang, S.4    Freeman III, M.E.5    Yi, Q.6
  • 29
    • 0037124307 scopus 로고    scopus 로고
    • Protein kinase Cβ controls nuclear factor κB activation in B cells through selective regulation of the IκB kinase α
    • K. Saijo, I. Mecklenbräuker, A. Santana, M. Leitger, C. Schmedt, A. Tarakhovsky, Protein kinase Cβ controls nuclear factor κB activation in B cells through selective regulation of the IκB kinase α. J. Exp. Med. 195, 1647-1652 (2002).
    • (2002) J. Exp. Med. , vol.195 , pp. 1647-1652
    • Saijo, K.1    Mecklenbräuker, I.2    Santana, A.3    Leitger, M.4    Schmedt, C.5    Tarakhovsky, A.6
  • 30
    • 0035869627 scopus 로고    scopus 로고
    • Protein kinase C and mitogen-activated protein kinase signalling in oligodendrocytes
    • R. L. Stariha, S. U. Kim, Protein kinase C and mitogen-activated protein kinase signalling in oligodendrocytes. Microsc. Res. Tech. 52, 680-688 (2001).
    • (2001) Microsc. Res. Tech. , vol.52 , pp. 680-688
    • Stariha, R.L.1    Kim, S.U.2
  • 31
    • 0035834240 scopus 로고    scopus 로고
    • A PKCβ isoform mediates phorbol ester-induced activation of Erk1/2 and expression of neuronal differentiation genes in neuroblastoma cells
    • U. Trollér, R. Zeidman, K. Svensson, C. Larsson, A PKCβ isoform mediates phorbol ester-induced activation of Erk1/2 and expression of neuronal differentiation genes in neuroblastoma cells. FEBS Lett. 508, 126-130 (2001).
    • (2001) FEBS Lett. , vol.508 , pp. 126-130
    • Trollér, U.1    Zeidman, R.2    Svensson, K.3    Larsson, C.4
  • 35
    • 0031985121 scopus 로고    scopus 로고
    • Insulin regulates protein kinase CßII expression through enhanced exon inclusion in L6 skeletal muscle cells. A novel mechanism of insulin- and insulin-like growth factor-I-induced 5′ splice site selection
    • C. E. Chalfant, J. E.Watson, L. D. Bisnauth, J. B. Kang, N. Patel, L. M. Obeid, D. C. Eichler, D. R. Cooper, Insulin regulates protein kinase CßII expression through enhanced exon inclusion in L6 skeletal muscle cells. A novel mechanism of insulin- and insulin-like growth factor-I-induced 5′ splice site selection. J. Biol. Chem. 273, 910- 916 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 910-916
    • Chalfant, C.E.1    Watson, J.E.2    Bisnauth, L.D.3    Kang, J.B.4    Patel, N.5    Obeid, L.M.6    Eichler, D.C.7    Cooper, D.R.8
  • 36
  • 37
    • 79952015621 scopus 로고    scopus 로고
    • Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients
    • P. Ravishankaran, R. Karunanithi, Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients. World J. Surg. Oncol. 9, 18 (2011).
    • (2011) World J. Surg. Oncol. , vol.9 , pp. 18
    • Ravishankaran, P.1    Karunanithi, R.2
  • 40
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • J. E. Darnell Jr., STATs and gene regulation. Science 277, 1630-1635 (1997).
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell Jr., J.E.1
  • 42
    • 0042622239 scopus 로고    scopus 로고
    • NEBcutter: A program to cleave DNA with restriction enzymes
    • T. Vincze, J. Posfai, R. J. Roberts, NEBcutter: A program to cleave DNA with restriction enzymes. Nucleic Acids Res. 31, 3688-3691 (2003).
    • (2003) Nucleic Acids Res. , vol.31 , pp. 3688-3691
    • Vincze, T.1    Posfai, J.2    Roberts, R.J.3
  • 44
    • 84859200990 scopus 로고    scopus 로고
    • Activation of Stat3 in endothelial cells following hypoxia-reoxygenation is mediated by Rac1 and protein kinase C
    • S. N. Mattagajasingh, X. P. Yang, K. Irani, I. Mattagajasingh, L. C. Becker, Activation of Stat3 in endothelial cells following hypoxia-reoxygenation is mediated by Rac1 and protein kinase C. Biochim. Biophys. Acta 1823, 997-1006 (2012).
    • (2012) Biochim. Biophys. Acta , vol.1823 , pp. 997-1006
    • Mattagajasingh, S.N.1    Yang, X.P.2    Irani, K.3    Mattagajasingh, I.4    Becker, L.C.5
  • 46
    • 0027143992 scopus 로고
    • Normal breast epithelial cells produce interleukins 6 and 8 together with tumor-necrosis factor: Defective IL6 expression in mammary carcinoma
    • F. Basolo, P. G. Conaldi, L. Fiore, S. Calvo, A. Toniolo, Normal breast epithelial cells produce interleukins 6 and 8 together with tumor-necrosis factor: Defective IL6 expression in mammary carcinoma. Int. J. Cancer 55, 926-930 (1993).
    • (1993) Int. J. Cancer , vol.55 , pp. 926-930
    • Basolo, F.1    Conaldi, P.G.2    Fiore, L.3    Calvo, S.4    Toniolo, A.5
  • 47
    • 0030034383 scopus 로고    scopus 로고
    • Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines
    • J. J. Chiu, M. K. Sgagias, K. H. Cowan, Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines. Clin. Cancer Res. 2, 215-221 (1996).
    • (1996) Clin. Cancer Res. , vol.2 , pp. 215-221
    • Chiu, J.J.1    Sgagias, M.K.2    Cowan, K.H.3
  • 48
    • 34548125294 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses
    • I. Fricke, N. Mirza, J. Dupont, C. Lockhart, A. Jackson, J. H. Lee, J. A. Sosman, D. I. Gabrilovich, Vascular endothelial growth factor-trap overcomes defects in dendritic cell differentiation but does not improve antigen-specific immune responses. Clin. Cancer Res. 13, 4840-4848 (2007).
    • (2007) Clin. Cancer Res. , vol.13 , pp. 4840-4848
    • Fricke, I.1    Mirza, N.2    Dupont, J.3    Lockhart, C.4    Jackson, A.5    Lee, J.H.6    Sosman, J.A.7    Gabrilovich, D.I.8
  • 49
    • 0028059490 scopus 로고
    • Agonists and antagonists of protein kinase C function, derived from its binding proteins
    • D. Ron, D. Mochly-Rosen, Agonists and antagonists of protein kinase C function, derived from its binding proteins. J. Biol. Chem. 269, 21395-21398 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 21395-21398
    • Ron, D.1    Mochly-Rosen, D.2
  • 51
    • 38149119710 scopus 로고    scopus 로고
    • Protein kinase C-β inhibitor enzastaurin (LY317615.HCI) enhances radiation control of murine breast cancer in an orthotopic model of bone metastasis
    • A. Z. Dudek, P. Zwolak, P. Jasinski, K. Terai, N. J. Gallus, M. E. Ericson, F. Farassati, Protein kinase C-β inhibitor enzastaurin (LY317615.HCI) enhances radiation control of murine breast cancer in an orthotopic model of bone metastasis. Invest. New Drugs 26, 13-24 (2008).
    • (2008) Invest. New Drugs , vol.26 , pp. 13-24
    • Dudek, A.Z.1    Zwolak, P.2    Jasinski, P.3    Terai, K.4    Gallus, N.J.5    Ericson, M.E.6    Farassati, F.7
  • 52
    • 77957708324 scopus 로고    scopus 로고
    • Phase II, double-blind, randomized trial of capecitabine plus enzastaurin versus capecitabine plus placebo in patients with metastatic or recurrent breast cancer after prior anthracycline and taxane therapy
    • M. Clemons, A. A. Joy, R. Abdulnabi, M. Kotliar, J. Lynch, J. P. Jordaan, N. Iscoe, K. Gelmon, Phase II, double-blind, randomized trial of capecitabine plus enzastaurin versus capecitabine plus placebo in patients with metastatic or recurrent breast cancer after prior anthracycline and taxane therapy. Breast Cancer Res. Treat. 124, 177-186 (2010).
    • (2010) Breast Cancer Res. Treat. , vol.124 , pp. 177-186
    • Clemons, M.1    Joy, A.A.2    Abdulnabi, R.3    Kotliar, M.4    Lynch, J.5    Jordaan, J.P.6    Iscoe, N.7    Gelmon, K.8
  • 53
    • 33749318608 scopus 로고    scopus 로고
    • Establishing a cancer center data bank and biorepository for multidisciplinary research
    • C. B. Ambrosone, M. K. Nesline, W. Davis, Establishing a cancer center data bank and biorepository for multidisciplinary research. Cancer Epidemiol. Biomarkers Prev. 15, 1575-1577 (2006).
    • (2006) Cancer Epidemiol. Biomarkers Prev. , vol.15 , pp. 1575-1577
    • Ambrosone, C.B.1    Nesline, M.K.2    Davis, W.3
  • 55
    • 0029960028 scopus 로고    scopus 로고
    • Dominant negative Stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction
    • A. Kaptein, V. Paillard, M. Saunders, Dominant negative Stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction. J. Biol. Chem. 271, 5961-5964 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 5961-5964
    • Kaptein, A.1    Paillard, V.2    Saunders, M.3
  • 56
    • 4444226259 scopus 로고    scopus 로고
    • Multiparametric flow cytometric analysis of inter-patient variation in STAT1 phosphorylation following interferon alfa immunotherapy
    • G. B. Lesinski, S. V. Kondadasula, T. Crespin, L. Shen, K. Kendra, M.Walker,W. E. Carson III, Multiparametric flow cytometric analysis of inter-patient variation in STAT1 phosphorylation following interferon alfa immunotherapy. J. Natl. Cancer Inst. 96, 1331-1342 (2004).
    • (2004) J. Natl. Cancer Inst. , vol.96 , pp. 1331-1342
    • Lesinski, G.B.1    Kondadasula, S.V.2    Crespin, T.3    Shen, L.4    Kendra, K.5    Walker, M.6    Carson III, W.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.