-
1
-
-
0031661632
-
Immunotherapy and experimental approaches for metastatic melanoma
-
Atkins MB. Immunotherapy and experimental approaches for metastatic melanoma. Hematol Oncol Clin North Am 1998;12:877-902.
-
(1998)
Hematol. Oncol. Clin. North Am.
, vol.12
, pp. 877-902
-
-
Atkins, M.B.1
-
2
-
-
0036534376
-
Interferon alfa therapy for malignant melanoma: A systematic review of randomized controlled trials
-
Lens MB, Dawes M. Interferon alfa therapy for malignant melanoma: a systematic review of randomized controlled trials. J Clin Oncol 2002;20: 1818-25.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1818-1825
-
-
Lens, M.B.1
Dawes, M.2
-
3
-
-
0035339880
-
High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: Results of intergroup trial E1694/S9512/C509801
-
Kirkwood JM, Ibrahim JG, Sosman JA, Sondak VK, Agarwala SS, Ernstoff MS, et al. High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801. J Clin Oncol 2001;19:2370-80.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 2370-2380
-
-
Kirkwood, J.M.1
Ibrahim, J.G.2
Sosman, J.A.3
Sondak, V.K.4
Agarwala, S.S.5
Ernstoff, M.S.6
-
4
-
-
85047689957
-
The anti-tumor effects of interferon-alpha are abrogated in a STAT1-deficient mouse
-
Lesinski GB, Anghelina M, Zimmerer J, Bakalakos T, Badgwell B, Parihar R, et al. The anti-tumor effects of interferon-alpha are abrogated in a STAT1-deficient mouse. J Clin Invest 2003;112:170-80.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 170-180
-
-
Lesinski, G.B.1
Anghelina, M.2
Zimmerer, J.3
Bakalakos, T.4
Badgwell, B.5
Parihar, R.6
-
5
-
-
0033957167
-
T-cell recognition of melanoma-associated antigens
-
Castelli C, Rivoltini L, Andreola G, Carrabba M, Renkvist N, Parmiani G. T-cell recognition of melanoma-associated antigens. J Cell Physiol 2000; 182:323-31.
-
(2000)
J. Cell Physiol.
, vol.182
, pp. 323-331
-
-
Castelli, C.1
Rivoltini, L.2
Andreola, G.3
Carrabba, M.4
Renkvist, N.5
Parmiani, G.6
-
6
-
-
0029875179
-
Immunohistochemical detection of the type I interferon receptor in human fetal, adult, and neoplastic tissues
-
Navarro S, Colamonici OR, Llombart-Bosch A. Immunohistochemical detection of the type I interferon receptor in human fetal, adult, and neoplastic tissues. Mod Pathol 1996;9:150-6.
-
(1996)
Mod. Pathol.
, vol.9
, pp. 150-156
-
-
Navarro, S.1
Colamonici, O.R.2
Llombart-Bosch, A.3
-
7
-
-
0027170786
-
Effects of systemic interferon-alpha (IFN-alpha) on the antigenic phenotype of melanoma metastases. EORTC melanoma group cooperative study No. 18852
-
von Stamm U, Brocker EB, von Depka Prondzinski M, Ruiter DJ, Rumke P, Broding C, et al. Effects of systemic interferon-alpha (IFN-alpha) on the antigenic phenotype of melanoma metastases. EORTC melanoma group cooperative study No. 18852. Melanoma Res 1993;3:173-80.
-
(1993)
Melanoma Res.
, vol.3
, pp. 173-180
-
-
von Stamm, U.1
Brocker, E.B.2
von Depka Prondzinski, M.3
Ruiter, D.J.4
Rumke, P.5
Broding, C.6
-
8
-
-
0031915809
-
Signal transduction in the interferon system
-
Haque SJ, Williams BR. Signal transduction in the interferon system. Semin Oncol 1998;25:14-22.
-
(1998)
Semin. Oncol.
, vol.25
, pp. 14-22
-
-
Haque, S.J.1
Williams, B.R.2
-
9
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell JE Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994;264:1415-21.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, G.R.3
-
10
-
-
0023987751
-
Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control
-
Levy DE, Kessler DS, Pine R, Reich N, Darnell JE Jr. Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev 1988;2:383-93.
-
(1988)
Genes Dev.
, vol.2
, pp. 383-393
-
-
Levy, D.E.1
Kessler, D.S.2
Pine, R.3
Reich, N.4
Darnell Jr., J.E.5
-
11
-
-
0037097778
-
IFN-stimulated gene 15 is synergistically activated through interactions between the myelocyte/lymphocyte-specific transcription factors, PU.1, IFN regulatory factor-8/IFN consensus sequence binding protein, and IFN regulatory factor-4: Characterization of a new subtype of IFN-stimulated response element
-
Meraro D, Gleit-Kielmanowicz M, Hauser H, Levi BZ. IFN-stimulated gene 15 is synergistically activated through interactions between the myelocyte/lymphocyte-specific transcription factors, PU.1, IFN regulatory factor-8/IFN consensus sequence binding protein, and IFN regulatory factor-4: characterization of a new subtype of IFN-stimulated response element. J Immunol 2002;168:6224-31.
-
(2002)
J. Immunol.
, vol.168
, pp. 6224-6231
-
-
Meraro, D.1
Gleit-Kielmanowicz, M.2
Hauser, H.3
Levi, B.Z.4
-
12
-
-
0030036075
-
Identification of an intragenic interferon-stimulated response element sequence of the mouse class I major histocompatibility complex H-2Kb gene
-
Hatina VJ, Kralova J, Jansa P. Identification of an intragenic interferon-stimulated response element sequence of the mouse class I major histocompatibility complex H-2Kb gene. Exp Clin Immunogenet 1996;13:55-60.
-
(1996)
Exp. Clin. Immunogenet.
, vol.13
, pp. 55-60
-
-
Hatina, V.J.1
Kralova, J.2
Jansa, P.3
-
13
-
-
0029034506
-
The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-gamma and TNF-alpha
-
Ohmori Y, Hamilton TA. The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-gamma and TNF-alpha. J Immunol 1995;154:5235-44.
-
(1995)
J. Immunol.
, vol.154
, pp. 5235-5244
-
-
Ohmori, Y.1
Hamilton, T.A.2
-
14
-
-
0036791488
-
IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells
-
Parihar R, Dierksheide J, Hu Y, Carson WE. IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells. J Clin Invest 2002;110:983.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 983
-
-
Parihar, R.1
Dierksheide, J.2
Hu, Y.3
Carson, W.E.4
-
15
-
-
0032899422
-
Detection of intracellular phosphorylated STAT-1 by flow cytometry
-
Fleisher TA, Dorman SE, Anderson JA, Vail M, Brown MR, Holland SM. Detection of intracellular phosphorylated STAT-1 by flow cytometry. Clin Immunol 1999;90:425-30.
-
(1999)
Clin. Immunol.
, vol.90
, pp. 425-430
-
-
Fleisher, T.A.1
Dorman, S.E.2
Anderson, J.A.3
Vail, M.4
Brown, M.R.5
Holland, S.M.6
-
16
-
-
0037047333
-
Growth hormone-induced differential desensitization of STAT5, ERK, and Akt phosphorylation
-
Ji S, Frank SJ, Messina JL. Growth hormone-induced differential desensitization of STAT5, ERK, and Akt phosphorylation. J Biol Chem 2002;277: 28384-93.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 28384-28393
-
-
Ji, S.1
Frank, S.J.2
Messina, J.L.3
-
17
-
-
0027496114
-
A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
-
Sadowski HB, Shuai K, Darnell JE, Jr., Gilman MZ. A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science 1993;261:1739-44.
-
(1993)
Science
, vol.261
, pp. 1739-1744
-
-
Sadowski, H.B.1
Shuai, K.2
Darnell Jr., J.E.3
Gilman, M.Z.4
-
18
-
-
0031696748
-
Interferon-alpha-induced activation of signal transducer and activator of transcription proteins in malignant melanoma
-
Carson WE. Interferon-alpha-induced activation of signal transducer and activator of transcription proteins in malignant melanoma. Clin Cancer Res 1998;4:2219-28.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 2219-2228
-
-
Carson, W.E.1
-
19
-
-
0037297371
-
Generation of tumor cell lysate-loaded dendritic cells preprogrammed for IL-12 production and augmented T cell response
-
Vegh Z, Mazumder A. Generation of tumor cell lysate-loaded dendritic cells preprogrammed for IL-12 production and augmented T cell response. Cancer Immunol Immunother 2003;52:67-79.
-
(2003)
Cancer Immunol. Immunother.
, vol.52
, pp. 67-79
-
-
Vegh, Z.1
Mazumder, A.2
-
20
-
-
0004252445
-
-
4th ed. Upper Saddle River (NJ): Prentice-Hall
-
Zar JH. Biostatistical analysis. 4th ed. Upper Saddle River (NJ): Prentice-Hall; 1999. p. 136-9.
-
(1999)
Biostatistical Analysis
, pp. 136-169
-
-
Zar, J.H.1
-
21
-
-
0038515256
-
Gene expression profiling and functiorial activity of human dendritic cells induced with IFN-alpha-2b: Implications for cancer immunotherapy
-
Moschella F, Bisikirska B, Maffei A, Papadopoulos KP, Skerrett D, Liu Z, et al. Gene expression profiling and functiorial activity of human dendritic cells induced with IFN-alpha-2b: implications for cancer immunotherapy. Clin Cancer Res 2003;9:2022-31.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2022-2031
-
-
Moschella, F.1
Bisikirska, B.2
Maffei, A.3
Papadopoulos, K.P.4
Skerrett, D.5
Liu, Z.6
-
22
-
-
0036566673
-
Type I interferons produced by dendritic cells promote their phenotypic and functional activation
-
Montoya M, Schiavoni G, Mattei F, Gresser I, Belardelli F, Borrow P, et al. Type I interferons produced by dendritic cells promote their phenotypic and functional activation. Blood 2002;99:3263-71.
-
(2002)
Blood
, vol.99
, pp. 3263-3271
-
-
Montoya, M.1
Schiavoni, G.2
Mattei, F.3
Gresser, I.4
Belardelli, F.5
Borrow, P.6
-
23
-
-
0029042847
-
Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-in filtrating, gut mucosal and peripheral lymphocytes: Correlation with the stage of the disease
-
Matsuda M, Petersson M, Lenkei R, Taupin JL, Magnusson I, Mellstedt H, et al. Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-in filtrating, gut mucosal and peripheral lymphocytes: correlation with the stage of the disease. Int J Cancer 1995;61:765-72.
-
(1995)
Int. J. Cancer
, vol.61
, pp. 765-772
-
-
Matsuda, M.1
Petersson, M.2
Lenkei, R.3
Taupin, J.L.4
Magnusson, I.5
Mellstedt, H.6
-
24
-
-
0029737843
-
Expression and activity of signaling molecules in T lymphocytes obtained from patients with metastatic melanoma before and after interleukin 2 therapy
-
Rabinowich H, Banks M, Reichert TE, Logan TF, Kirkwood JM, Whiteside TL. Expression and activity of signaling molecules in T lymphocytes obtained from patients with metastatic melanoma before and after interleukin 2 therapy. Clin Cancer Res 1996;2:1263-74.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1263-1274
-
-
Rabinowich, H.1
Banks, M.2
Reichert, T.E.3
Logan, T.F.4
Kirkwood, J.M.5
Whiteside, T.L.6
-
25
-
-
0028829736
-
Alterations in T cell receptor and signal transduction molecules in melanoma patients
-
Zea AH, Curti BD, Longo DL, Alvord WG, Strobl SL, Mizoguchi H, et al. Alterations in T cell receptor and signal transduction molecules in melanoma patients. Clin Cancer Res 1995; 1: 1327-35.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 1327-1335
-
-
Zea, A.H.1
Curti, B.D.2
Longo, D.L.3
Alvord, W.G.4
Strobl, S.L.5
Mizoguchi, H.6
-
26
-
-
0021684554
-
Pharmacokinetics and tolerance of intravenous and intramuscular recombinant alpha 2 interferon in patients with malignancies
-
Shah I, Band J, Samson M, Young J, Robinson R, Bailey B, et al. Pharmacokinetics and tolerance of intravenous and intramuscular recombinant alpha 2 interferon in patients with malignancies. Am J Hematol 1984;17:363-71.
-
(1984)
Am. J. Hematol.
, vol.17
, pp. 363-371
-
-
Shah, I.1
Band, J.2
Samson, M.3
Young, J.4
Robinson, R.5
Bailey, B.6
-
27
-
-
0035870575
-
Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: Potential for pharmacodynamic monitoring of signal transduction inhibitors
-
Chow S, Patel H, Hedley DW. Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors. Cytometry 2001;46:72-8.
-
(2001)
Cytometry
, vol.46
, pp. 72-78
-
-
Chow, S.1
Patel, H.2
Hedley, D.W.3
-
29
-
-
0036173143
-
Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry
-
Perez OD, Nolan GP. Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry. Nat Biotechnol 2002;20:155-62.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 155-162
-
-
Perez, O.D.1
Nolan, G.P.2
-
30
-
-
0037452790
-
Individuality and variation in gene expression patterns in human blood
-
Whitney AR, Diehn M, Popper SJ, Alizadeh AA, Boldrick JC, Relman DA, et al. Individuality and variation in gene expression patterns in human blood. Proc Natl Acad Sci U S A 2003;100:1896-901.
-
(2003)
Proc. Natl. Acad. Sci. U S A
, vol.100
, pp. 1896-1901
-
-
Whitney, A.R.1
Diehn, M.2
Popper, S.J.3
Alizadeh, A.A.4
Boldrick, J.C.5
Relman, D.A.6
-
31
-
-
0027406425
-
T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors
-
Alexander JP, Kudoh S, Melsop KA, Hamilton TA, Edinger MG, Tubbs RR, et al. T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors. Cancer Res 1993;53:1380-7.
-
(1993)
Cancer Res.
, vol.53
, pp. 1380-1387
-
-
Alexander, J.P.1
Kudoh, S.2
Melsop, K.A.3
Hamilton, T.A.4
Edinger, M.G.5
Tubbs, R.R.6
-
32
-
-
0024245729
-
Proliferative and cytolytic potentials of purified human tumor-infiltrating T lymphocytes. Impaired response to mitogen-driven stimulation despite T-cell receptor expression
-
Miescher S, Stoeck M, Qiao L, Barras C, Barrelet L, von Fliedner V. Proliferative and cytolytic potentials of purified human tumor-infiltrating T lymphocytes. Impaired response to mitogen-driven stimulation despite T-cell receptor expression. Int J Cancer 1988;42:659-66.
-
(1988)
Int. J. Cancer
, vol.42
, pp. 659-666
-
-
Miescher, S.1
Stoeck, M.2
Qiao, L.3
Barras, C.4
Barrelet, L.5
von Fliedner, V.6
-
33
-
-
0032102948
-
Impaired expression and function of signal-transducing zeta chains in peripheral T cells and natural killer cells in patients with prostate cancer
-
Healy CG, Simons JW, Carducci MA, DeWeese TL, Bartkowski M, Tong KP, et al. Impaired expression and function of signal-transducing zeta chains in peripheral T cells and natural killer cells in patients with prostate cancer. Cytometry 1998;32:109-19.
-
(1998)
Cytometry
, vol.32
, pp. 109-119
-
-
Healy, C.G.1
Simons, J.W.2
Carducci, M.A.3
DeWeese, T.L.4
Bartkowski, M.5
Tong, K.P.6
-
34
-
-
0031774084
-
Impaired production of Th1 cytokines and increased frequency of Th2 subsets in PBMC from advanced cancer patients
-
Sato M, Goto S, Kaneko R, Ito M, Sato S, Takeuchi S. Impaired production of Th1 cytokines and increased frequency of Th2 subsets in PBMC from advanced cancer patients. Anticancer Res 1998;18:3951-5.
-
(1998)
Anticancer Res.
, vol.18
, pp. 3951-3955
-
-
Sato, M.1
Goto, S.2
Kaneko, R.3
Ito, M.4
Sato, S.5
Takeuchi, S.6
-
35
-
-
0032719554
-
Expression of angiogenic and immunosuppressive factors by uveal melanoma cell lines
-
IjIand SA, Jager MJ, Heijdra BM, Westphal JR, Peek R. Expression of angiogenic and immunosuppressive factors by uveal melanoma cell lines. Melanoma Res 1999;9:445-50.
-
(1999)
Melanoma Res.
, vol.9
, pp. 445-450
-
-
IjIand, S.A.1
Jager, M.J.2
Heijdra, B.M.3
Westphal, J.R.4
Peek, R.5
-
36
-
-
0034910296
-
Serum imbalance of cytokines in melanoma patients
-
Moretti S, Chiarugi A, Semplici F, Salvi A, De Giorgi V, Fabbri P, et al. Serum imbalance of cytokines in melanoma patients. Melanoma Res 2001; 11:395-9.
-
(2001)
Melanoma Res.
, vol.11
, pp. 395-399
-
-
Moretti, S.1
Chiarugi, A.2
Semplici, F.3
Salvi, A.4
De Giorgi, V.5
Fabbri, P.6
-
37
-
-
0028966911
-
Elevated serum levels of interleukin-10 in patients with metastatic malignant melanoma
-
Dummer W, Becker JC, Schwaaf A, Leverkus M, Moll T, Brocker EB. Elevated serum levels of interleukin-10 in patients with metastatic malignant melanoma. Melanoma Res 1995;5:67-8.
-
(1995)
Melanoma Res.
, vol.5
, pp. 67-68
-
-
Dummer, W.1
Becker, J.C.2
Schwaaf, A.3
Leverkus, M.4
Moll, T.5
Brocker, E.B.6
-
38
-
-
0033765387
-
Unexpected cytokines in serum of malignant melanoma patients during sequential biochemotherapy
-
Grimm EA, Smid CM, Lee JJ, Tseng CH, Eton O, Buzaid AC. Unexpected cytokines in serum of malignant melanoma patients during sequential biochemotherapy. Clin Cancer Res 2000;6:3895-903.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3895-3903
-
-
Grimm, E.A.1
Smid, C.M.2
Lee, J.J.3
Tseng, C.H.4
Eton, O.5
Buzaid, A.C.6
-
39
-
-
0029946548
-
Interleukin-6 production and secretion in human melanoma cell lines: Regulation by interleukin-1
-
Francis GM, Krohn EG, Woods KV, Buzaid AC, Grimm EA. Interleukin-6 production and secretion in human melanoma cell lines: regulation by interleukin-1. Melanoma Res 1996;6:191-201.
-
(1996)
Melanoma Res.
, vol.6
, pp. 191-201
-
-
Francis, G.M.1
Krohn, E.G.2
Woods, K.V.3
Buzaid, A.C.4
Grimm, E.A.5
-
40
-
-
0032822064
-
Differential increase of Fas ligand expression on metastatic and thin or thick primary melanoma cells compared with interleukin-10
-
Ekmekcioglu S, Okcu MF, Colome-Grimmer MI, Owen-Schaub L, Buzaid AC, Grimm EA. Differential increase of Fas ligand expression on metastatic and thin or thick primary melanoma cells compared with interleukin-10. Melanoma Res 1999;9:261-72.
-
(1999)
Melanoma Res.
, vol.9
, pp. 261-272
-
-
Ekmekcioglu, S.1
Okcu, M.F.2
Colome-Grimmer, M.I.3
Owen-Schaub, L.4
Buzaid, A.C.5
Grimm, E.A.6
-
41
-
-
4644325749
-
A phase I trial of interleukin-12 and interferon-alpha
-
[abstract 2242]
-
Carson WE, Sundaram P, Nadella P, Anghelina M, Dierksbeide S, Dierksheide J, et al. A phase I trial of interleukin-12 and interferon-alpha [abstract 2242]. Proc ASCO 2000;19:569a.
-
(2000)
Proc. ASCO
, vol.19
-
-
Carson, W.E.1
Sundaram, P.2
Nadella, P.3
Anghelina, M.4
Dierksbeide, S.5
Dierksheide, J.6
|