The interaction between β1 integrins and ERK1/2 in osteogenic differentiation of human mesenchymal stem cells under fluid shear stress modelled by a perfusion system

Journal of Tissue Engineering and Regenerative Medicine

Volumn 8, Issue 2, 2014, Pages 85-96

  Liu, Liyue ^a,b   Zong, Chen ^a   Li, Bo ^c   Shen, Dan ^c   Tang, Zihua ^a   Chen, Jiarong ^a   Zheng, Qiang ^c   Tong, Xiangming ^c   Gao, Changyou ^b   Wang, Jinfu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b NINGDE NORMAL UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

ERK1 2; Fluid shear stress; Human mesenchymal stem cells; Osteogenic differentiation; 1 integrins

Indexed keywords

CELL CULTURE; CELL ENGINEERING; CHEMICAL ACTIVATION; GENE EXPRESSION; MONOCLONAL ANTIBODIES; PHOSPHORYLATION; SHEAR STRESS; STEM CELLS;

BIOMECHANICAL FACTORS; ERK1/2; FLUID SHEAR STRESS; HUMAN MESENCHYMAL STEM CELLS; INTEGRINS; OSTEOGENIC DIFFERENTIATION; PERFUSION SYSTEM; STRESS-INDUCED; UP-REGULATION; Β1 INTEGRIN;

GLYCOPROTEINS;

ALP PROTEIN; BETA1 INTEGRIN; COLI ALPHA PROTEIN; FOCAL ADHESION KINASE 1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; OCN PROTEIN; PROTEIN; TISSUE SCAFFOLD; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ADHERENT CELL; ADIPOCYTE; ADULT; ARTICLE; BONE MARROW CULTURE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN EXPERIMENT; MECHANORECEPTOR; MESENCHYMAL STEM CELL; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; OSTEOGENIC DIFFERENTIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; SHEAR STRESS; SIGNAL TRANSDUCTION; UPREGULATION;

ERK1/2; FLUID SHEAR STRESS; HUMAN MESENCHYMAL STEM CELLS; OSTEOGENIC DIFFERENTIATION; Β1 INTEGRINS;

ADULT; ALKALINE PHOSPHATASE; ANTIGENS, CD29; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B PROTEINS; LACTIC ACID; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; MODELS, BIOLOGICAL; OSTEOCALCIN; OSTEOGENESIS; PERFUSION; PHOSPHORYLATION; POLYGLYCOLIC ACID; SHEAR STRENGTH; STRESS, MECHANICAL; TISSUE SCAFFOLDS; TRANSCRIPTION FACTOR RELA; YOUNG ADULT;

EID: 84894267811     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1498     Document Type: Article

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