Structure-activity relationship of selected Meta-and Para-hydroxylated non-dioxin like polychlorinated biphenyls: From single RyR1 channels to muscle dysfunction

Toxicological Sciences

Volumn 136, Issue 2, 2013, Pages 500-513

  Niknam, Yassaman ^a   Feng, Wei ^a   Cherednichenko, Gennady ^a   Dong, Yao ^a   Joshi, Sudhir N ^b   Vyas, Sandhya M ^b   Lehmler, Hans Joachim ^b   Pessah, I N ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Calcium signaling; Hydroxylated metabolites; Muscle dysfunction; Polychlorinated biphenyls; Ryanodine receptor

Indexed keywords

CAFFEINE; DIOXIN; META HYDROXYLATED NON DIOXIN LIKE POLYCHLORINATED BIPHENYL; PARA HYDROXYLATED NON DIOXIN LIKE POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL DERIVATIVE; RYANODINE RECEPTOR 1; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM SIGNALING; CHANNEL GATING; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; HYDROXYLATION; MICROSOME; MOTOR DYSFUNCTION; MOUSE; MUSCLE CELL; MUSCLE DISEASE; MYOTUBE; NONHUMAN; PROBABILITY; SARCOPLASMIC RETICULUM; STRUCTURE ACTIVITY RELATION; VOLTAGE CLAMP;

CALCIUM SIGNALING; HYDROXYLATED METABOLITES.; MUSCLE DYSFUNCTION; POLYCHLORINATED BIPHENYLS; RYANODINE RECEPTOR;

ANIMALS; CALCIUM; CELLS, CULTURED; MICE; MICE, INBRED C57BL; MUSCLE CONTRACTION; MUSCLE, SKELETAL; POLYCHLORINATED BIPHENYLS; RABBITS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84888071230     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft202     Document Type: Article

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