Comparative antagonist pharmacology at the native mouse bradykinin B 2 receptor: Radioligand binding and smooth muscle contractility studies

British Journal of Pharmacology

Volumn 150, Issue 3, 2007, Pages 313-320

  Meini, S ^a   Cucchi, P ^a   Bellucci, F ^a   Catalani, C ^a   Giuliani, S ^a   Santicioli, P ^a   Maggi, C A ^a  

^a Menarini Ricerche SpA   (Italy)

Author keywords

Airways; FR173657; Icatibant; Ileum; LF16 0687; Lung; MEN11270; MEN16132; Non peptide; Peptide

Indexed keywords

3 (6 ACETAMIDO 3 PYRIDYL) N [N [2,4 DICHLORO 3 [(2 METHYL 8 QUINOLINYL)OXYMETHYL]PHENYL] N METHYLAMINOCARBONYLMETHYL]ACRYLAMIDE; 4 AMINO 5 [4 [4 [2,4 DICHLORO 3 (2,4 DIMETHYL 8 QUINOLYLOXYMETHYL) PHENYLSULFONAMIDO]TETRAHYDRO 2H 4 PYRANYLCARBONYL]PIPERAZINO] 5 OXOPENTYL TRIMETHYLAMMONIUM CHLORIDE; ANATIBANT; BRADYKININ; BRADYKININ B1 RECEPTOR; BRADYKININ B2 RECEPTOR; BRADYKININ B2 RECEPTOR ANTAGONIST; FR 73657; ICATIBANT; MEN 11270; MEN 16132; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BIOASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG BINDING SITE; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; ILEUM; ILEUM CONTRACTION; ISOTOPE LABELING; LIGAND BINDING; LUNG PARENCHYMA; MALE; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTILITY;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ILEUM; LUNG; MALE; MICE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; ORNITHINE; RADIOLIGAND ASSAY; RECEPTOR, BRADYKININ B2; SULFONAMIDES;

EID: 33846874995     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706995     Document Type: Article

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