Orexin-A-induced ERK1/2 activation reverses impaired spatial learning and memory in pentylenetetrazol-kindled rats via OX1R-mediated hippocampal neurogenesis

Peptides

Volumn 54, Issue , 2014, Pages 140-147

  Zhao, Xuan ^a   Zhang, Rui Xue ^a   Tang, Shi ^a   Ren, Yan Yan ^a   Yang, Wei Xia ^a   Liu, Xiao Min ^a   Tang, Ji You ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Epilepsy; ERK1 2; Learning and memory; Neurogenesis; Orexin A; OX1R

Indexed keywords

1-(2-METHYLBENZOXAZOL-6-YL)-3-(1,5)NAPHTHYRIDIN-4-YL UREA; BENZOXAZOLE DERIVATIVE; HCRTR1 PROTEIN, RAT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROPEPTIDE; OREXIN RECEPTOR; OREXINS; PENTETRAZOLE; SIGNAL PEPTIDE; UREA;

ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; ENZYME ACTIVATION; HIPPOCAMPUS; MALE; MAZE TEST; MEMORY; METABOLISM; NERVOUS SYSTEM DEVELOPMENT; SPATIAL LEARNING; WISTAR RAT;

ANIMALS; BENZOXAZOLES; ENZYME ACTIVATION; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MAZE LEARNING; MEMORY; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUROGENESIS; NEUROPEPTIDES; OREXIN RECEPTORS; PENTYLENETETRAZOLE; RATS, WISTAR; SPATIAL LEARNING; UREA;

EID: 84894256957     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2013.11.019     Document Type: Article

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