BDNF and exercise enhance neuronal DNA repair by stimulating CREB-mediated production of apurinic/apyrimidinic endonuclease 1

NeuroMolecular Medicine

Volumn 16, Issue 1, 2014, Pages 161-174

  Yang, Jenq Lin ^a,b   Lin, Yu Ting ^b   Chuang, Pei Chin ^b   Bohr, Vilhelm A ^a   Mattson, Mark P ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Akt kinase; Alzheimer; Base excision repair; Comet assay; Exercise; Oxidative stress; Running; Synaptic plasticity

Indexed keywords

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL CORTEX; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; ENZYME INDUCTION; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURONS; PHYSICAL CONDITIONING, ANIMAL; PROTO-ONCOGENE PROTEINS C-AKT; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; RNA INTERFERENCE; RNA, SMALL INTERFERING; VITAMIN K 3;

EID: 84894249687     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-013-8270-x     Document Type: Article

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