-
1
-
-
0034056789
-
Is microalbuminuria a predictor of cardiovascular and renal disease in patients with essential hypertension?
-
Campese VM, Bianchi S, Bigazzi R. Is microalbuminuria a predictor of cardiovascular and renal disease in patients with essential hypertension? Curr Opin Nephrol Hypertens 2000; 9:143-147.
-
(2000)
Curr Opin Nephrol Hypertens
, vol.9
, pp. 143-147
-
-
Campese, V.M.1
Bianchi, S.2
Bigazzi, R.3
-
2
-
-
79954469664
-
Renal injury in angiotensin IINAME-induced hypertensive rats is independent of elevated blood pressure
-
Polichnowski AJ, Lu L, Cowley AW, Jr. Renal injury in angiotensin IINAME-induced hypertensive rats is independent of elevated blood pressure. Am J Physiol Renal Physiol 2011; 300:F1008-F1016.
-
(2011)
Am J Physiol Renal Physiol
, vol.300
-
-
Polichnowski, A.J.1
Lu, L.2
Cowley Jr., A.W.3
-
3
-
-
79952278420
-
Hypertension and kidney disease
-
Ritz E. Hypertension and kidney disease. Clin Nephrol 2010; 74:S39-S43.
-
(2010)
Clin Nephrol
, vol.74
-
-
Ritz, E.1
-
4
-
-
70349659185
-
Angiotensin II induces connective tissue growth factor and collagen i expression via transforming growth factor-beta-dependent and-independent Smad pathways: The role of Smad3
-
Yang F, Chung AC, Huang XR, Lan HY. Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and-independent Smad pathways: the role of Smad3. Hypertension 2009; 54:877-884.
-
(2009)
Hypertension
, vol.54
, pp. 877-884
-
-
Yang, F.1
Chung, A.C.2
Huang, X.R.3
Lan, H.Y.4
-
5
-
-
45149121685
-
Kidney fibrosis in hypertensive rats: Role of oxidative stress
-
Zhao W, Chen SS, Chen Y, Ahokas RA, Sun Y. Kidney fibrosis in hypertensive rats: role of oxidative stress. Am J Nephrol 2008; 28:548-554.
-
(2008)
Am J Nephrol
, vol.28
, pp. 548-554
-
-
Zhao, W.1
Chen, S.S.2
Chen, Y.3
Ahokas, R.A.4
Sun, Y.5
-
6
-
-
69549110735
-
Fluorofenidone attenuates collagen i and transforming growth factor-beta1 expression through a nicotinamide adenine dinucleotide phosphate oxidase-dependent way in NRK-52E cells
-
Peng ZZ, Hu GY, Shen H, Wang L, Ning WB, Xie YY, Wang NS, Li BX, Tang YT, Tao LJ. Fluorofenidone attenuates collagen I and transforming growth factor-beta1 expression through a nicotinamide adenine dinucleotide phosphate oxidase-dependent way in NRK-52E cells. Nephrology (Carlton) 2009; 14:565-572.
-
(2009)
Nephrology (Carlton)
, vol.14
, pp. 565-572
-
-
Peng, Z.Z.1
Hu, G.Y.2
Shen, H.3
Wang, L.4
Ning, W.B.5
Xie, Y.Y.6
Wang, N.S.7
Li, B.X.8
Tang, Y.T.9
Tao, L.J.10
-
7
-
-
62949101948
-
NADPH oxidases and angiotensin II receptor signaling
-
Garrido AM, Griendling KK. NADPH oxidases and angiotensin II receptor signaling. Mol Cell Endocrinol 2009; 302:148-158.
-
(2009)
Mol Cell Endocrinol
, vol.302
, pp. 148-158
-
-
Garrido, A.M.1
Griendling, K.K.2
-
8
-
-
77953808712
-
Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation
-
Leask A. Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation. Circ Res 2010; 106:1675-1680.
-
(2010)
Circ Res
, vol.106
, pp. 1675-1680
-
-
Leask, A.1
-
9
-
-
58149127646
-
PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta
-
Kawai T, Masaki T, Doi S, Arakawa T, Yokoyama Y, Doi T, Kohno N, Yorioka N. PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta. Lab Invest 2009; 89:47-58.
-
(2009)
Lab Invest
, vol.89
, pp. 47-58
-
-
Kawai, T.1
Masaki, T.2
Doi, S.3
Arakawa, T.4
Yokoyama, Y.5
Doi, T.6
Kohno, N.7
Yorioka, N.8
-
10
-
-
54249163313
-
The role of inflammatory markers in the cardioprotective effect of L-carnitine in L-NAME-induced hypertension
-
Miguel-Carrasco JL, Mate A, Monserrat MT, Arias JL, Aramburu O, Vazquez CM. The role of inflammatory markers in the cardioprotective effect of L-carnitine in L-NAME-induced hypertension. Am J Hypertens 2008; 21:1231-1237.
-
(2008)
Am J Hypertens
, vol.21
, pp. 1231-1237
-
-
Miguel-Carrasco, J.L.1
Mate, A.2
Monserrat, M.T.3
Arias, J.L.4
Aramburu, O.5
Vazquez, C.M.6
-
11
-
-
0033854954
-
Molecular plasticity of vascular wall during N(G)-nitro-L-arginine methyl ester-induced hypertension: Modulation of proinflammatory signals
-
Gonzalez W, Fontaine V, Pueyo ME, Laquay N, Messika-Zeitoun D, Philippe M, Arnal JF, Jacob MP, Michel JB. Molecular plasticity of vascular wall during N(G)-nitro-L-arginine methyl ester-induced hypertension: modulation of proinflammatory signals. Hypertension 2000; 36:103-109.
-
(2000)
Hypertension
, vol.36
, pp. 103-109
-
-
Gonzalez, W.1
Fontaine, V.2
Pueyo, M.E.3
Laquay, N.4
Messika-Zeitoun, D.5
Philippe, M.6
Arnal, J.F.7
Jacob, M.P.8
Michel, J.B.9
-
12
-
-
0036882119
-
PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation
-
Diep QN, Amiri F, Touyz RM, Cohn JS, Endemann D, Neves MF, Schiffrin EL. PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation. Hypertension 2002; 40:866-871.
-
(2002)
Hypertension
, vol.40
, pp. 866-871
-
-
Diep, Q.N.1
Amiri, F.2
Touyz, R.M.3
Cohn, J.S.4
Endemann, D.5
Neves, M.F.6
Schiffrin, E.L.7
-
13
-
-
84874558989
-
Chronic inhibition of PPAR-gamma signaling induces endothelial dysfunction in the juvenile lamb
-
Sharma S, Barton J, Rafikov R, Aggarwal S, Kuo HC, Oishi PE, Datar SA, Fineman JR, Black SM. Chronic inhibition of PPAR-gamma signaling induces endothelial dysfunction in the juvenile lamb. Pulm Pharmacol Ther 2013; 26:271-280.
-
(2013)
Pulm Pharmacol Ther
, vol.26
, pp. 271-280
-
-
Sharma, S.1
Barton, J.2
Rafikov, R.3
Aggarwal, S.4
Kuo, H.C.5
Oishi, P.E.6
Datar, S.A.7
Fineman, J.R.8
Black, S.M.9
-
14
-
-
84866017810
-
Telmisartan counteracts TGF-beta1 induced epithelial-to-mesenchymal transition via PPAR-gamma in human proximal tubule epithelial cells
-
Chen Y, Luo Q, Xiong Z, Liang W, Chen L, Xiong Z. Telmisartan counteracts TGF-beta1 induced epithelial-to-mesenchymal transition via PPAR-gamma in human proximal tubule epithelial cells. Int J Clin Exp Pathol 2012; 5:522-529.
-
(2012)
Int J Clin Exp Pathol
, vol.5
, pp. 522-529
-
-
Chen, Y.1
Luo, Q.2
Xiong, Z.3
Liang, W.4
Chen, L.5
Xiong, Z.6
-
15
-
-
77955251736
-
Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components
-
Martin H. Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components. Mutat Res 2010; 690:57-63.
-
(2010)
Mutat Res
, vol.690
, pp. 57-63
-
-
Martin, H.1
-
16
-
-
0032189158
-
Effect of l-carnitine on the status of lipid peroxidation and antioxidants in aging rats
-
Kalaiselvi T, Panneerselvam C. Effect of l-carnitine on the status of lipid peroxidation and antioxidants in aging rats. J Nutr Biochem 1998; 9:575-581.
-
(1998)
J Nutr Biochem
, vol.9
, pp. 575-581
-
-
Kalaiselvi, T.1
Panneerselvam, C.2
-
17
-
-
0034994973
-
Protective role of L-carnitine on liver and heart lipid peroxidation in atherosclerotic rats
-
Dayanandan A, Kumar P, Panneerselvam C. Protective role of L-carnitine on liver and heart lipid peroxidation in atherosclerotic rats. J Nutr Biochem 2001; 12:254-257.
-
(2001)
J Nutr Biochem
, vol.12
, pp. 254-257
-
-
Dayanandan, A.1
Kumar, P.2
Panneerselvam, C.3
-
18
-
-
0034834828
-
L-carnitine prevents the progression of atherosclerotic lesions in hypercholesterolaemic rabbits
-
Sayed-Ahmed MM, Khattab MM, Gad MZ, Mostafa N. L-carnitine prevents the progression of atherosclerotic lesions in hypercholesterolaemic rabbits. Pharmacol Res 2001; 44:235-242.
-
(2001)
Pharmacol Res
, vol.44
, pp. 235-242
-
-
Sayed-Ahmed, M.M.1
Khattab, M.M.2
Gad, M.Z.3
Mostafa, N.4
-
19
-
-
2042460866
-
L-carnitine ameliorates oxidative damage due to chronic renal failure in rats
-
Sener G, Paskaloglu K, Satiroglu H, Alican I, Kacmaz A, Sakarcan A. L-carnitine ameliorates oxidative damage due to chronic renal failure in rats. J Cardiovasc Pharmacol 2004; 43:698-705.
-
(2004)
J Cardiovasc Pharmacol
, vol.43
, pp. 698-705
-
-
Sener, G.1
Paskaloglu, K.2
Satiroglu, H.3
Alican, I.4
Kacmaz, A.5
Sakarcan, A.6
-
20
-
-
77349090650
-
Comparative effects of captopril and l-carnitine on blood pressure and antioxidant enzyme gene expression in the heart of spontaneously hypertensive rats
-
Miguel-Carrasco JL, Monserrat MT, Mate A, Vazquez CM. Comparative effects of captopril and l-carnitine on blood pressure and antioxidant enzyme gene expression in the heart of spontaneously hypertensive rats. Eur J Pharmacol 2010; 632:65-72.
-
(2010)
Eur J Pharmacol
, vol.632
, pp. 65-72
-
-
Miguel-Carrasco, J.L.1
Monserrat, M.T.2
Mate, A.3
Vazquez, C.M.4
-
21
-
-
77954818479
-
The therapeutic prospects of using L-carnitine to manage hypertension-related organ damage
-
Mate A, Miguel-Carrasco JL, Vazquez CM. The therapeutic prospects of using L-carnitine to manage hypertension-related organ damage. Drug Discov Today 2010; 15:484-492.
-
(2010)
Drug Discov Today
, vol.15
, pp. 484-492
-
-
Mate, A.1
Miguel-Carrasco, J.L.2
Vazquez, C.M.3
-
22
-
-
79955441980
-
A combination of (omega-3) polyunsaturated fatty acids, polyphenols and L-carnitine reduces the plasma lipid levels and increases the expression of genes involved in fatty acid oxidation in human peripheral blood mononuclear cells and HepG2 cells
-
Radler U, Stangl H, Lechner S, Lienbacher G, Krepp R, Zeller E, Brachinger M, Eller-Berndl D, Fischer A, Anzur C, Schoerg G, Mascher D, Laschan C, Anderwald C, Lohninger A. A combination of (omega-3) polyunsaturated fatty acids, polyphenols and L-carnitine reduces the plasma lipid levels and increases the expression of genes involved in fatty acid oxidation in human peripheral blood mononuclear cells and HepG2 cells. Ann Nutr Metab 2011; 58:133-140.
-
(2011)
Ann Nutr Metab
, vol.58
, pp. 133-140
-
-
Radler, U.1
Stangl, H.2
Lechner, S.3
Lienbacher, G.4
Krepp, R.5
Zeller, E.6
Brachinger, M.7
Eller-Berndl, D.8
Fischer, A.9
Anzur, C.10
Schoerg, G.11
Mascher, D.12
Laschan, C.13
Anderwald, C.14
Lohninger, A.15
-
23
-
-
84874666148
-
L-Carnitine protects against arterial hypertension-related cardiac fibrosis through modulation of PPAR-gamma expression
-
Zambrano S, Blanca AJ, Ruiz-Armenta MV, Miguel-Carrasco JL, Arevalo M, Vazquez MJ, Mate A, Vazquez CM. L-Carnitine protects against arterial hypertension-related cardiac fibrosis through modulation of PPAR-gamma expression. Biochem Pharmacol 2013; 85:937-944.
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 937-944
-
-
Zambrano, S.1
Blanca, A.J.2
Ruiz-Armenta, M.V.3
Miguel-Carrasco, J.L.4
Arevalo, M.5
Vazquez, M.J.6
Mate, A.7
Vazquez, C.M.8
-
24
-
-
84857470016
-
The mouse gene encoding the carnitine biosynthetic enzyme 4-N-trimethylaminobutyraldehyde dehydrogenase is regulated by peroxisome proliferator-activated receptor alpha
-
Wen G, Ringseis R, Rauer C, Eder K. The mouse gene encoding the carnitine biosynthetic enzyme 4-N-trimethylaminobutyraldehyde dehydrogenase is regulated by peroxisome proliferator-activated receptor alpha. Biochim Biophys Acta 2012; 1819:357-365.
-
(2012)
Biochim Biophys Acta
, vol.1819
, pp. 357-365
-
-
Wen, G.1
Ringseis, R.2
Rauer, C.3
Eder, K.4
-
25
-
-
70349490367
-
Peroxisome proliferator-activated receptor alpha plays a crucial role in L-carnitine anti-apoptosis effect in renal tubular cells
-
Chen HH, Sue YM, Chen CH, Hsu YH, Hou CC, Cheng CY, Lin SL, Tsai WL, Chen TW, Chen TH. Peroxisome proliferator-activated receptor alpha plays a crucial role in L-carnitine anti-apoptosis effect in renal tubular cells. Nephrol Dial Transplant 2009; 24:3042-3049.
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 3042-3049
-
-
Chen, H.H.1
Sue, Y.M.2
Chen, C.H.3
Hsu, Y.H.4
Hou, C.C.5
Cheng, C.Y.6
Lin, S.L.7
Tsai, W.L.8
Chen, T.W.9
Chen, T.H.10
-
27
-
-
77954562244
-
L-carnitine treatment in patients with mild diastolic heart failure is associated with improvement in diastolic function and symptoms
-
Serati AR, Motamedi MR, Emami S, Varedi P, Movahed MR. L-carnitine treatment in patients with mild diastolic heart failure is associated with improvement in diastolic function and symptoms. Cardiology 2010; 116:178-182.
-
(2010)
Cardiology
, vol.116
, pp. 178-182
-
-
Serati, A.R.1
Motamedi, M.R.2
Emami, S.3
Varedi, P.4
Movahed, M.R.5
-
28
-
-
3042716265
-
Imidapril improves L-NAME-exacerbated nephrosclerosis with TGF-beta 1 inhibition in spontaneously hypertensive rats
-
Ono H, Saitoh M, Ono Y, Ishimitu T, Matsuoka H. Imidapril improves L-NAME-exacerbated nephrosclerosis with TGF-beta 1 inhibition in spontaneously hypertensive rats. J Hypertens 2004; 22:1389-1395.
-
(2004)
J Hypertens
, vol.22
, pp. 1389-1395
-
-
Ono, H.1
Saitoh, M.2
Ono, Y.3
Ishimitu, T.4
Matsuoka, H.5
-
29
-
-
59149091009
-
Connective tissue growth factor and cardiac fibrosis
-
Daniels A, van Bilsen M, Goldschmeding R, van der Vusse GJ, V, van Nieuwenhoven FA. Connective tissue growth factor and cardiac fibrosis. Acta Physiol (Oxf) 2009; 195:321-338.
-
(2009)
Acta Physiol (Oxf)
, vol.195
, pp. 321-338
-
-
Daniels, A.1
Van Bilsen, M.2
Goldschmeding, R.3
Van Der Vusse, G.J.V.4
Van Nieuwenhoven, F.A.5
-
30
-
-
78751656380
-
Novel Nox homologues in the vasculature: Focusing on Nox4 and Nox5
-
Montezano AC, Burger D, Ceravolo GS, Yusuf H, Montero M, Touyz RM. Novel Nox homologues in the vasculature: focusing on Nox4 and Nox5. Clin Sci (Lond) 2011; 120:131-141.
-
(2011)
Clin Sci (Lond)
, vol.120
, pp. 131-141
-
-
Montezano, A.C.1
Burger, D.2
Ceravolo, G.S.3
Yusuf, H.4
Montero, M.5
Touyz, R.M.6
-
31
-
-
79955021142
-
Effect of eplerenone on hypertension-associated renal damage in rats: Potential role of peroxisome proliferator activated receptor gamma (PPARgamma)
-
Miana M, de Las HN, Rodriguez C, Sanz-Rosa D, Martin-Fernandez B, Mezzano S, Lahera V, Martinez-Gonzalez J, Cachofeiro V. Effect of eplerenone on hypertension-associated renal damage in rats: potential role of peroxisome proliferator activated receptor gamma (PPARgamma). J Physiol Pharmacol 2011; 62:87-94.
-
(2011)
J Physiol Pharmacol
, vol.62
, pp. 87-94
-
-
Miana, M.1
De Las, H.N.2
Rodriguez, C.3
Sanz-Rosa, D.4
Martin-Fernandez, B.5
Mezzano, S.6
Lahera, V.7
Martinez-Gonzalez, J.8
Cachofeiro, V.9
-
32
-
-
77649148275
-
Propionyl-L-carnitine improves postischemic blood flow recovery and arteriogenetic revascularization and reduces endothelial NADPHoxidase 4-mediated superoxide production
-
Stasi MA, Scioli MG, Arcuri G, Mattera GG, Lombardo K, Marcellini M, Riccioni T, De FS, Pisano C, Spagnoli LG, Borsini F, Orlandi A. Propionyl-L-carnitine improves postischemic blood flow recovery and arteriogenetic revascularization and reduces endothelial NADPHoxidase 4-mediated superoxide production. Arterioscler Thromb Vasc Biol 2010; 30:426-435.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 426-435
-
-
Stasi, M.A.1
Scioli, M.G.2
Arcuri, G.3
Mattera, G.G.4
Lombardo, K.5
Marcellini, M.6
Riccioni, T.7
De Fs Pisano, C.8
Spagnoli, L.G.9
Borsini, F.10
Orlandi, A.11
-
33
-
-
0037225664
-
Carnitine inhibits arachidonic acid turnover, platelet function, and oxidative stress
-
Pignatelli P, Lenti L, Sanguigni V, Frati G, Simeoni I, Gazzaniga PP, Pulcinelli FM, Violi F. Carnitine inhibits arachidonic acid turnover, platelet function, and oxidative stress. Am J Physiol Heart Circ Physiol 2003; 284:H41-H48.
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.284
-
-
Pignatelli, P.1
Lenti, L.2
Sanguigni, V.3
Frati, G.4
Simeoni, I.5
Gazzaniga, P.P.6
Pulcinelli, F.M.7
Violi, F.8
-
34
-
-
77949471906
-
L-carnitine attenuates cardiac remodelling rather than vascular remodelling in deoxycorticosterone acetate-salt hypertensive rats
-
O'Brien D, Chunduri P, Iyer A, Brown L. L-carnitine attenuates cardiac remodelling rather than vascular remodelling in deoxycorticosterone acetate-salt hypertensive rats. Basic Clin Pharmacol Toxicol 2010; 106:296-301.
-
(2010)
Basic Clin Pharmacol Toxicol
, vol.106
, pp. 296-301
-
-
O'Brien, D.1
Chunduri, P.2
Iyer, A.3
Brown, L.4
-
35
-
-
84865529392
-
L-Carnitine prevents the development of ventricular fibrosis and heart failure with preserved ejection fraction in hypertensive heart disease
-
Omori Y, Ohtani T, Sakata Y, Mano T, Takeda Y, Tamaki S, Tsukamoto Y, Kamimura D, Aizawa Y, Miwa T, Komuro I, Soga T, Yamamoto K. L-Carnitine prevents the development of ventricular fibrosis and heart failure with preserved ejection fraction in hypertensive heart disease. J Hypertens 2012; 30:1834-1844.
-
(2012)
J Hypertens
, vol.30
, pp. 1834-1844
-
-
Omori, Y.1
Ohtani, T.2
Sakata, Y.3
Mano, T.4
Takeda, Y.5
Tamaki, S.6
Tsukamoto, Y.7
Kamimura, D.8
Aizawa, Y.9
Miwa, T.10
Komuro, I.11
Soga, T.12
Yamamoto, K.13
-
36
-
-
0042626565
-
L-carnitine transport in kidney of normotensive, Wistar-Kyoto rats: Effect of chronic L-carnitine administration
-
Gomez-Amores L, Mate A, Vazquez CM. L-carnitine transport in kidney of normotensive, Wistar-Kyoto rats: effect of chronic L-carnitine administration. Pharm Res 2003; 20:1133-1140.
-
(2003)
Pharm Res
, vol.20
, pp. 1133-1140
-
-
Gomez-Amores, L.1
Mate, A.2
Vazquez, C.M.3
-
37
-
-
73649124171
-
The role of peroxisome proliferator-activated receptor alpha in transcriptional regulation of novel organic cation transporters
-
Eder K, Ringseis R. The role of peroxisome proliferator-activated receptor alpha in transcriptional regulation of novel organic cation transporters. Eur J Pharmacol 2010; 628:1-5.
-
(2010)
Eur J Pharmacol
, Issue.628
, pp. 1-5
-
-
Eder, K.1
Ringseis, R.2
-
38
-
-
67349232471
-
Tei index: The earliest detectable cardiac structural and functional abnormality detectable in Hb Bart's foetal edema
-
Chao G, Zheng C, Meng D, Su J, Xie X, Li W, Henein M. Tei index: the earliest detectable cardiac structural and functional abnormality detectable in Hb Bart's foetal edema. Int J Cardiol 2009; 134:e150-e154.
-
(2009)
Int J Cardiol
, vol.134
-
-
Chao, G.1
Zheng, C.2
Meng, D.3
Su, J.4
Xie, X.5
Li, W.6
Henein, M.7
-
39
-
-
0027361036
-
Effects of carnitine and its congeners on eicosanoid discharge from rat cells: Implications for release of TNFalpha
-
Garrelds IM, Elliott GR, Pruimboom WM, Zijlstra FJ, Bonta IL. Effects of carnitine and its congeners on eicosanoid discharge from rat cells: implications for release of TNFalpha. Mediators Inflamm 1993; 2:S57-S62.
-
(1993)
Mediators Inflamm
, vol.2
-
-
Garrelds, I.M.1
Elliott, G.R.2
Pruimboom, W.M.3
Zijlstra, F.J.4
Bonta, I.L.5
|