메뉴 건너뛰기




Volumn 284, Issue 1 53-1, 2003, Pages

Carnitine inhibits arachidonic acid turnover, platelet function, and oxidative stress

Author keywords

Oxygen free radicals

Indexed keywords

ARACHIDONIC ACID; CALCIUM ION; CARNITINE; COLLAGEN; PHOSPHOLIPASE A2; PHOSPHOLIPID; PROTEIN KINASE C; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; THROMBOXANE A2;

EID: 0037225664     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00249.2002     Document Type: Article
Times cited : (85)

References (40)
  • 1
    • 0033563816 scopus 로고    scopus 로고
    • Lucigenin is a mediator of cytochrome C reduction but not of superoxide production
    • Afanas'ev IB, Ostrachovitch EA, and Korkina LG. Lucigenin is a mediator of cytochrome C reduction but not of superoxide production. Arch Biochem Biophys 366: 267-274, 1999.
    • (1999) Arch Biochem Biophys , vol.366 , pp. 267-274
    • Afanas'ev, I.B.1    Ostrachovitch, E.A.2    Korkina, L.G.3
  • 2
    • 0026622948 scopus 로고
    • Role of carnitine and carnitine palmitoyl-transferase as integral components of the pathway for membranephospholipid fatty acid turnover in intact human erythrocytes
    • Arduini A, Mancinelli G, Radatti GL, Dottori S, Molajoni F, and Ramsay RR. Role of carnitine and carnitine palmitoyl-transferase as integral components of the pathway for membranephospholipid fatty acid turnover in intact human erythrocytes. J Biol Chem 267: 12673-12681, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 12673-12681
    • Arduini, A.1    Mancinelli, G.2    Radatti, G.L.3    Dottori, S.4    Molajoni, F.5    Ramsay, R.R.6
  • 3
    • 0032211437 scopus 로고    scopus 로고
    • Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical
    • Benov L, Sztejnberg L, and Fridovich L. Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical. Free Radic Biol Med 25: 826-831, 1998.
    • (1998) Free Radic Biol Med , vol.25 , pp. 826-831
    • Benov, L.1    Sztejnberg, L.2    Fridovich, L.3
  • 5
    • 0028972482 scopus 로고
    • 2 is phosphorylated in collagen- and thrombin-stimulated human platelets independent of protein kinase C and mitogen-activated protein kinase
    • 2 is phosphorylated in collagen- and thrombin-stimulated human platelets independent of protein kinase C and mitogen-activated protein kinase. J Biol Chem 270: 25885- 25892, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 25885-25892
    • Borsch-Haubold, A.1    Kramer, R.M.2    Watson, S.P.3
  • 6
    • 0034983085 scopus 로고    scopus 로고
    • Arachidonic acid as a bioactive molecule
    • Brash AR. Arachidonic acid as a bioactive molecule. J Clin Invest 107: 1339-1345, 2001.
    • (2001) J Clin Invest , vol.107 , pp. 1339-1345
    • Brash, A.R.1
  • 7
    • 0022340109 scopus 로고
    • 2+ mobilization and granule secretion in platelets
    • 2+ mobilization and granule secretion in platelets. J Biol Chem 260: 15172-15179, 1985.
    • (1985) J Biol Chem , vol.260 , pp. 15172-15179
    • Brass, L.F.1    Joseph, S.K.2
  • 8
    • 0001145160 scopus 로고    scopus 로고
    • Superoxide anion and hydroxyl radical release by collagen-induced platelet aggregation-role of arachidonic acid metabolism
    • Caccese D, Pratico D, Ghiselli A, Natoli S, Pignatelli P, Sanguigni V, Iuliano L, and Violi F. Superoxide anion and hydroxyl radical release by collagen-induced platelet aggregation-role of arachidonic acid metabolism. Thromb Haemost 83: 485-490, 2000.
    • (2000) Thromb Haemost , vol.83 , pp. 485-490
    • Caccese, D.1    Pratico, D.2    Ghiselli, A.3    Natoli, S.4    Pignatelli, P.5    Sanguigni, V.6    Iuliano, L.7    Violi, F.8
  • 9
    • 0028181632 scopus 로고
    • The requirement for phospholipase A 2 for activation of the assembled NADPH oxidase in humanneutrophils
    • Dana R, Malech HL, and Levy R. The requirement for phospholipase A2 for activation of the assembled NADPH oxidase in humanneutrophils. Biochem J 297: 217-223, 1994.
    • (1994) Biochem J , vol.297 , pp. 217-223
    • Dana, R.1    Malech, H.L.2    Levy, R.3
  • 10
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch M, Lees M, and Sloane-Slanley M. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497-506, 1957.
    • (1957) J Biol Chem , vol.226 , pp. 497-506
    • Folch, M.1    Lees, M.2    Sloane-Slanley, M.3
  • 11
    • 0031770339 scopus 로고    scopus 로고
    • Nitric oxide and superoxide detection in human platelet
    • Freedman JE and Keaney JF. Nitric oxide and superoxide detection in human platelet. Methods Enzymol 301: 61-70, 1999.
    • (1999) Methods Enzymol , vol.301 , pp. 61-70
    • Freedman, J.E.1    Keaney, J.F.2
  • 12
    • 0021895138 scopus 로고
    • 2+ indicators with greatly improved fluorescence properties
    • 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 13
    • 0028068186 scopus 로고
    • Free radicals, antioxidant, and human disease: Curiosity, cause, or consequence
    • Halliwell B. Free radicals, antioxidant, and human disease: Curiosity, cause, or consequence. Lancet 344: 721-724, 1994.
    • (1994) Lancet , vol.344 , pp. 721-724
    • Halliwell, B.1
  • 15
    • 0023161282 scopus 로고
    • Nutritional regulation of cellular phosphatidyl inositol
    • Holub BJ and Skeaff CL. Nutritional regulation of cellular phosphatidyl inositol. Methods Enzymol 141: 234-242, 1987.
    • (1987) Methods Enzymol , vol.141 , pp. 234-242
    • Holub, B.J.1    Skeaff, C.L.2
  • 17
    • 0034696612 scopus 로고    scopus 로고
    • Radiolabeled native low-density lipoprotein injected into patients with carotid stenosis accumulates in macrophages of atherosclerotic plaque
    • Iuliano L, Mauriello NM, Sbarigia E, Spagnoli LG, and Violi F. Radiolabeled native low-density lipoprotein injected into patients with carotid stenosis accumulates in macrophages of atherosclerotic plaque. Circulation 101: 1249-1254, 2000.
    • (2000) Circulation , vol.101 , pp. 1249-1254
    • Iuliano, L.1    Mauriello, N.M.2    Sbarigia, E.3    Spagnoli, L.G.4    Violi, F.5
  • 18
    • 0032995139 scopus 로고    scopus 로고
    • Substrate utilization and work efficiency during submaximal exercise in vitamin C depleted-repleted adults
    • Johnston CS, Swan PD, and Corte C. Substrate utilization and work efficiency during submaximal exercise in vitamin C depleted-repleted adults. Int J Vitam Nutr Res 69: 41-44, 1999.
    • (1999) Int J Vitam Nutr Res , vol.69 , pp. 41-44
    • Johnston, C.S.1    Swan, P.D.2    Corte, C.3
  • 19
    • 0034717940 scopus 로고    scopus 로고
    • Fatty acid import into mitochondria
    • Kerner J and Hoppel C. Fatty acid import into mitochondria. Biochim Biophys Acta 1486: 1-17, 2000.
    • (2000) Biochim Biophys Acta , vol.1486 , pp. 1-17
    • Kerner, J.1    Hoppel, C.2
  • 20
    • 0029029066 scopus 로고
    • Arachidonic acid and free fatty acids as second messangers and the role of protein kinase C
    • Khan WA, Blobe GC, and Hannun YA. Arachidonic acid and free fatty acids as second messangers and the role of protein kinase C. Cell Signal 3: 171-184, 1995.
    • (1995) Cell Signal , vol.3 , pp. 171-184
    • Khan, W.A.1    Blobe, G.C.2    Hannun, Y.A.3
  • 21
    • 0025178862 scopus 로고
    • Protein structure and properties of a secretable phospholipase A2 from human platelets
    • Kramer RM, Johansen B, Hession C, and Pepinsky RB. Protein structure and properties of a secretable phospholipase A2 from human platelets. Adv Exp Med Biol 275: 35-53, 1990.
    • (1990) Adv Exp Med Biol , vol.275 , pp. 35-53
    • Kramer, R.M.1    Johansen, B.2    Hession, C.3    Pepinsky, R.B.4
  • 24
    • 0030989642 scopus 로고    scopus 로고
    • Lucigenin (bis-N-methylacridinium) as a mediator of superoxide anion production
    • Liochev SI and Fridovich I. Lucigenin (bis-N-methylacridinium) as a mediator of superoxide anion production. Arch Biochem Biophys 337: 115-120, 1997.
    • (1997) Arch Biochem Biophys , vol.337 , pp. 115-120
    • Liochev, S.I.1    Fridovich, I.2
  • 27
    • 0025895541 scopus 로고
    • Free radical scavenging is involved in the protective effect of L-propionyl-carnitine against ischemia-reperfusion injury of the heart
    • Packer L, Valenza M, Serbinova E, Starke-Reed P, Frost K, and Kagan V. Free radical scavenging is involved in the protective effect of L-propionyl-carnitine against ischemia-reperfusion injury of the heart. Arch Biochem Biophys 288: 533-537, 1991.
    • (1991) Arch Biochem Biophys , vol.288 , pp. 533-537
    • Packer, L.1    Valenza, M.2    Serbinova, E.3    Starke-Reed, P.4    Frost, K.5    Kagan, V.6
  • 28
    • 0031962580 scopus 로고    scopus 로고
    • Hydrogen peroxide is involved in collagen-induced platelet activation
    • Pignatelli P, Pulcinelli FM, Lenti L, Gazzaniga PP, and Violi F. Hydrogen peroxide is involved in collagen-induced platelet activation. Blood 91: 484-490, 1998.
    • (1998) Blood , vol.91 , pp. 484-490
    • Pignatelli, P.1    Pulcinelli, F.M.2    Lenti, L.3    Gazzaniga, P.P.4    Violi, F.5
  • 32
    • 0025218905 scopus 로고
    • Flow cytometric analysis of respiratory burst activity in phagocytes with hydroetidine and 2,7-dichlorofluorescin
    • Rothe G and Valet G. Flow cytometric analysis of respiratory burst activity in phagocytes with hydroetidine and 2,7-dichlorofluorescin. J Leukoc Biol 47: 440-448, 1990.
    • (1990) J Leukoc Biol , vol.47 , pp. 440-448
    • Rothe, G.1    Valet, G.2
  • 33
    • 0034607649 scopus 로고    scopus 로고
    • Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase
    • Sciose A and Sumimoto H. Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase. J Biol Chem 275: 13793-13801, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 13793-13801
    • Sciose, A.1    Sumimoto, H.2
  • 35
    • 0035800889 scopus 로고    scopus 로고
    • Methods of detection of vascular reactive species: Nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite
    • Tarpey M and Fridovich L. Methods of detection of vascular reactive species: Nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite. Circ Res 89: 224-236, 2001.
    • (2001) Circ Res , vol.89 , pp. 224-236
    • Tarpey, M.1    Fridovich, L.2
  • 36
    • 0032865073 scopus 로고    scopus 로고
    • Inhibition of platelet-activating factor synthesis in human neutrophils and platelets by propionyl-L-carnitine
    • Triggiani M, Oriente A, Golino P, Gentile P, Battaglia C, Brevetti G, and Marone G. Inhibition of platelet-activating factor synthesis in human neutrophils and platelets by propionyl-L-carnitine. Biochem Pharmacol 58: 1341-1348, 1999.
    • (1999) Biochem Pharmacol , vol.58 , pp. 1341-1348
    • Triggiani, M.1    Oriente, A.2    Golino, P.3    Gentile, P.4    Battaglia, C.5    Brevetti, G.6    Marone, G.7
  • 38
    • 0242502758 scopus 로고    scopus 로고
    • Superoxide anion formation from lucigenin: An electron spin resonance spintrapping study
    • Vasquez-Vivar J, Hogg N, and Pritchard A Jr. Superoxide anion formation from lucigenin: An electron spin resonance spintrapping study. FEBS Lett 403: 127-130, 1997.
    • (1997) FEBS Lett , vol.403 , pp. 127-130
    • Vasquez-Vivar, J.1    Hogg, N.2    Pritchard A., Jr.3
  • 40
    • 0027938706 scopus 로고
    • Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation
    • Zweier JL, Broderick R, Kuppursamy P, Thompson-Gorman S, and Lutty GA. Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation. J Biol Chem 269: 24156-24162, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 24156-24162
    • Zweier, J.L.1    Broderick, R.2    Kuppursamy, P.3    Thompson-Gorman, S.4    Lutty, G.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.