메뉴 건너뛰기




Volumn 25, Issue 3, 2014, Pages 177-183

PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice

Author keywords

auditory hair cells; auditory progenitors; p27kip1, PTEN PI3K Akt signaling pathway; PTEN

Indexed keywords

ANIMALS; CELL COUNT; CELL CYCLE; COCHLEA; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOWN-REGULATION; EAR, INNER; HAIR CELLS, AUDITORY; HAIR CELLS, AUDITORY, INNER; HAIR CELLS, AUDITORY, OUTER; MICE; MICE, KNOCKOUT; NEURAL STEM CELLS; NEUROGENESIS; PAX2 TRANSCRIPTION FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION;

EID: 84894187964     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0000000000000069     Document Type: Article
Times cited : (22)

References (21)
  • 1
    • 0014040729 scopus 로고
    • Development of the inner ear of the mouse: A radioautographic study of terminal mitoses
    • Ruben RJ. Development of the inner ear of the mouse: a radioautographic study of terminal mitoses. Acta Otolaryngol 1967;220:221-244.
    • (1967) Acta Otolaryngol , vol.220 , pp. 221-244
    • Ruben, R.J.1
  • 3
    • 26244455518 scopus 로고    scopus 로고
    • Keynote review: The auditory system, hearing loss and potential targets for drug development
    • DOI 10.1016/S1359-6446(05)03595-6, PII S1359644605035956
    • Holley MC. Keynote review: the auditory system, hearing loss and potential targets for drug development. Drug Discov Today 2005;10:1269-1282. (Pubitemid 41416699)
    • (2005) Drug Discovery Today , vol.10 , Issue.19 , pp. 1269-1282
    • Holley, M.C.1
  • 4
    • 0036471398 scopus 로고    scopus 로고
    • Revisiting cell fate specification in the inner ear
    • DOI 10.1016/S0959-4388(02)00287-8
    • Fekete DM, Wu DK. Revisiting cell fate specification in the inner ear. Curr Opin Neurobiol 2002;12:35-42. (Pubitemid 34175272)
    • (2002) Current Opinion in Neurobiology , vol.12 , Issue.1 , pp. 35-42
    • Fekete, D.M.1    Wu, D.K.2
  • 6
    • 4644342396 scopus 로고    scopus 로고
    • From placode to polarization: New tunes in inner ear development
    • DOI 10.1242/dev.01339
    • Barald KF, Kelley MW. From placode to polarization: new tunes in inner ear development. Development 2004;131:4119-4130. (Pubitemid 39276184)
    • (2004) Development , vol.131 , Issue.17 , pp. 4119-4130
    • Barald, K.F.1    Kelley, M.W.2
  • 7
    • 0032933174 scopus 로고    scopus 로고
    • P27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
    • Chen P, Segil N. P27Kip1 links cell proliferation to morphogenesis in the developing organ of orti. Development 1999;26:1581-1590. (Pubitemid 29204323)
    • (1999) Development , vol.126 , Issue.8 , pp. 1581-1590
    • Chen, P.1    Segil, N.2
  • 8
    • 0037047268 scopus 로고    scopus 로고
    • Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization
    • Fujita N, Sato S, Katayama K, Tsuruo T. Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization. J Biol Chem 2002;277:28706-28713.
    • (2002) J Biol Chem , vol.277 , pp. 28706-28713
    • Fujita, N.1    Sato, S.2    Katayama, K.3    Tsuruo, T.4
  • 9
    • 0030992837 scopus 로고    scopus 로고
    • Signalling through the lipid products of phosphoinositide-3-OH kinase
    • DOI 10.1038/42648
    • Toker A, Cantley LC. Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature 1997;7:673-676. (Pubitemid 27270600)
    • (1997) Nature , vol.387 , Issue.6634 , pp. 673-676
    • Toker, A.1    Cantley, L.C.2
  • 11
    • 0027404833 scopus 로고
    • Ultrastructural evidence for hair cell regeneration in the mammalian inner ear
    • Forge A, Li L, Corwin JT, Nevill G. Ultrastructural evidence for hair cell regeneration in the mammalian inner ear. Science 1993;259:1616-1619. (Pubitemid 23114642)
    • (1993) Science , vol.259 , Issue.5101 , pp. 1616-1619
    • Forge, A.1    Li, L.2    Corwin, J.T.3    Nevill, G.4
  • 14
    • 77957152376 scopus 로고    scopus 로고
    • Phosophatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea
    • Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain MA, et al. Phosophatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea. Neuroscience 2010;170:1304-1313.
    • (2010) Neuroscience , vol.170 , pp. 1304-1313
    • Dong, Y.1    Sui, L.2    Yamaguchi, F.3    Kamitori, K.4    Hirata, Y.5    Hossain, M.A.6
  • 16
    • 77954035907 scopus 로고    scopus 로고
    • Role of phosphatase and tensin homolog in the development of the mammalian auditory system
    • Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Suzuki A, et al. Role of phosphatase and tensin homolog in the development of the mammalian auditory system. NeuroReport 2010;21:731-735.
    • (2010) NeuroReport , vol.21 , pp. 731-735
    • Dong, Y.1    Sui, L.2    Yamaguchi, F.3    Kamitori, K.4    Hirata, Y.5    Suzuki, A.6
  • 17
    • 77952668622 scopus 로고    scopus 로고
    • PTEN attenuates PIP3/Akt signaling in the cochlea of the aging CBA/J mouse
    • Sha SH, Chen FQ, Schacht J. PTEN attenuates PIP3/Akt signaling in the cochlea of the aging CBA/J mouse. Hear Res 2010;264:86-92.
    • (2010) Hear Res , vol.264 , pp. 86-92
    • Sha, S.H.1    Chen, F.Q.2    Schacht, J.3
  • 19
    • 0036195102 scopus 로고    scopus 로고
    • Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene
    • DOI 10.1002/gene.10036
    • Lesche R, Groszer M, Gao J, Wang Y, Messing A, Sun H, et al. Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene. Genesis 2002;32:148-149. (Pubitemid 34211723)
    • (2002) Genesis , vol.32 , Issue.2 , pp. 148-149
    • Lesche, R.1    Groszer, M.2    Gao, J.3    Wang, Y.4    Messing, A.5    Sun, H.6    Liu, X.7    Wu, H.8
  • 20
    • 2342510998 scopus 로고    scopus 로고
    • Generation of Pax2-Cre mice by modification of a Pax2 bacterial artificial chromosome
    • Takahiro O, Andrew KG. Generation of Pax2-Cre mice by modification of a Pax2 bacterial artificial chromosome. Genesis 2004;38:195-199.
    • (2004) Genesis , vol.38 , pp. 195-199
    • Takahiro, O.1    Andrew, K.G.2
  • 21
    • 0031870959 scopus 로고    scopus 로고
    • Pten is essential for embryonic development and tumour suppression
    • DOI 10.1038/1235
    • Di CA, Pesce B, Cordon-Cardo C, Pandolfi PP. Pten is essential for embryonic development and tumour suppression. Nat Genet 1998;19:348-355. (Pubitemid 28357906)
    • (1998) Nature Genetics , vol.19 , Issue.4 , pp. 348-355
    • Di Cristofano, A.1    Pesce, B.2    Cordon-Cardo, C.3    Pandolfi, P.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.