Revisiting cell fate specification in the inner ear

Current Opinion in Neurobiology

Volumn 12, Issue 1, 2002, Pages 35-42

  Fekete, Donna M ^a   Wu, Doris K ^b  

^a PURDUE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR; TRANSCRIPTION FACTOR;

CELL FATE; CELL INTERACTION; CELL LINEAGE; CELL TYPE; GENE CONTROL; GENE EXPRESSION; GENE TARGETING; HAIR CELL; INNER EAR; MECHANORECEPTOR; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SENSE ORGAN;

EID: 0036471398     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(02)00287-8     Document Type: Review

References (65)

1. Cell fate specification in the inner ear
2. Competence, specification and commitment in otic placode induction
3. Identification of synergistic signals initiating inner ear development
4. Induction of inner ear fate by FGF3
5. Compartment boundaries: At the edge of development
6. Molecular genetics of pattern formation in the inner ear: Do compartment boundaries play a role?
7. The expression domain of two related homeobox genes defines a compartment in the chicken inner ear that may be involved in semicircular canal formation
8. Regionalized organizing activity of the neural tube revealed by the regulation of lmx1 in the otic vesicle
9. Two regulatory genes, cNkx5-1 and cPax2, show different responses to local signals during otic placode and vesicle formation in the chick embryo
10. Expression of Pax2 and patterning of the chick inner ear
11. The role of FGF-3 in early inner ear development: An analysis in normal and kreisler mutant mice
12. Axial specification for sensory organs versus non-sensory structures of the chicken inner ear
13. A fate map of chick otic cup closure reveals lineage boundaries in the dorsal otocyst
14. Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervation
15. Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems
16. NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development
17. Transcription factor GATA-3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the ear
18. Fgf/Fgfr-2 (IIIb) signaling is essential for inner ear morphogenesis
19. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia
20. Making and breaking the innervation of the ear: Neurotrophic support during ear development and its clinical implications
21. Notch signaling in the development of the inner ear: Lessons from Drosophila
22. Developmental evolutionary biology of the vertebrate ear: Conserving mechanoelectric transduction and developmental pathways in diverging morphologies
23. Lineage analysis in the chicken inner ear shows differences in clonal dispersion for epithelial, neuronal, and mesenchymal cells
24. Sensory organ generation in the chicken inner ear: Contributions of bone morphogenetic protein 4, serrate 1, and lunatic fringe
25. Correlation of the development of membranous and bony labyrinths, acoustics ganglia, nerves, and brain centers of the chick embryos
26. Ectopic noggin blocks sensory and nonsensory organ morphogenesis in the chicken inner ear
27. Addition of the BMP4 antagonist, noggin, disrupts avian inner ear development
28. A family of mammalian fringe genes implicated in boundary determination and the Notch pathway
29. lunatic fringe is an essential mediator of somite segmentation and patterning
30. Fringe modulates Notch-ligand interactions
31. Dorsal-ventral signaling in the eye
32. Defects in somite formation in lunatic fringe-deficient mice
33. Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation
34. radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb
35. The Notch ligand Jagged1 is required for inner ear sensory development
36. The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti
37. Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear
38. Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear
39. Regionalized expression of Nkx5-1, Nkx5-2, Pax2 and sek genes during mouse inner ear development
40. Pax2 contributes to inner ear patterning and optic nerve trajectory
41. Otx1 null mutants show partial segregation of sensory epithelia comparable to lamprey ears
42. Otx1 and Otx2 activities are required for the normal development of the mouse inner ear
43. Origins of inner ear sensory organs revealed by fate map and time-lapse analyses
44. Hair cells and supporting cells share a common progenitor in the avian inner ear
45. Cell fate choices and the expression of Notch, Delta and Serrate homologues in the chick inner ear: Parallels with sense-organ development
46. Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear
47. Expression of proneural and neurogenic genes in the embryonic mammalian vestibular system
48. Notch signaling regulates the pattern of auditory hair cell differentiation in mammals
49. Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear
50. Hes1 is a negative regulator of inner ear hair cell differentiation
51. Notch signalling pathway mediates hair cell development in mammalian cochlea
52. A mutation in the lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea
53. The deltaA gene of zebrafish mediates lateral inhibition of hair cells in the inner ear and is regulated by Pax2.1
54. Delta-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: Evidence from the mind bomb mutant
55. Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system
56. Basic helix-loop-helix genes in neural development
57. The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation
58. Expression of Math1 and Hes5 in the cochleae of wildtype and Jag2 mutant mice
59. Math1: An essential gene for the generation of inner ear hair cells
60. Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears
61. Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development
62. Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development
63. Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells
64. + channel splice variants among hair cells along the tonotopic axis of the chick cochlea
65. + channel isoforms along the tonotopic gradient of the chicken's cochlea