Exploring the formation and recognition of an important G-quadruplex in a HIF1α promoter and its transcriptional inhibition by a benzo[c]phenanthridine derivative

Journal of the American Chemical Society

Volumn 136, Issue 6, 2014, Pages 2583-2591

  Chen, Han ^a   Long, Haitao ^a,c   Cui, Xiaojie ^a   Zhou, Jiang ^a   Xu, Ming ^b   Yuan, Gu ^a  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY THIRD HOSPITAL   (China)

^c BEIJING INSTITUTE OF TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOATES; BLOTTING, WESTERN; CIRCULAR DICHROISM; DRUG DESIGN; G-QUADRUPLEXES; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PHENANTHRIDINES; PROMOTER REGIONS, GENETIC;

EID: 84894179731     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja412128w     Document Type: Article

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