Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity

European Journal of Medicinal Chemistry

Volumn 75, Issue , 2014, Pages 222-232

  Matera, Carlo ^a   Flammini, Lisa ^b   Quadri, Marta ^a   Vivo, Valentina ^b   Ballabeni, Vigilio ^b   Holzgrabe, Ulrike ^c   Mohr, Klaus ^d   De Amici, Marco ^a   Barocelli, Elisabetta ^b   Bertoni, Simona ^b   Dallanoce, Clelia ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF BONN   (Germany)

Author keywords

Alkylbisammonio quaternary salts; Analgesic activity; In vitro pharmacology; In vivo pharmacology; Muscarinic agonists; Muscarinic receptor subtypes

Indexed keywords

ALKYLBISAMMONIO QUATERNARY SALTS; ANALGESIC ACTIVITY; IN VITRO PHARMACOLOGY; IN VIVO PHARMACOLOGY; MUSCARINIC AGONISTS; MUSCARINIC RECEPTOR SUBTYPES;

ALKANES; AMMONIUM COMPOUNDS; ANALGESICS; ANIMALS; CHOLINESTERASE INHIBITORS; FEMALE; GUINEA PIGS; MALE; MICE; MUSCARINIC AGONISTS; RABBITS; RATS; RATS, WISTAR; RECEPTORS, MUSCARINIC;

EID: 84894109151     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.01.032     Document Type: Article

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