Elucidating the adaptation and temporal coordination of metabolic pathways using in-silico evolution

BioSystems

Volumn 117, Issue 1, 2014, Pages 68-76

  Gottstein, Willi ^a   Müller, Stefan ^b,c   Herzel, Hanspeter ^d   Steuer, Ralf ^a,c  

^a HUMBOLDT UNIVERSITY   (Germany)

^b JOHANN RADON INSTITUTE FOR COMPUTATIONAL AND APPLIED MATHEMATICS   (Austria)

^c INSTITUTE OF MATHEMATICS   (Czech Republic)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Evolutionary algorithms; Flux balance analysis; Metabolic oscillations; Metabolism; Systems biology

Indexed keywords

ADAPTATION; METABOLISM; NUTRIENT AVAILABILITY; RESOURCE ALLOCATION; TOPOLOGY;

ARTICLE; CELL GROWTH; CELL METABOLISM; CELL POPULATION; COMPUTER SIMULATION; EVOLUTIONARY ADAPTATION; METABOLIC REGULATION; NUTRIENT AVAILABILITY; RESOURCE ALLOCATION;

EVOLUTIONARY ALGORITHMS; FLUX-BALANCE ANALYSIS; METABOLIC OSCILLATIONS; METABOLISM; SYSTEMS BIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ALGORITHMS; ANIMALS; BIOLOGICAL CLOCKS; COMPUTER SIMULATION; EVOLUTION, MOLECULAR; HUMANS; METABOLIC FLUX ANALYSIS; METABOLOME; MODELS, GENETIC; SIGNAL TRANSDUCTION;

EID: 84894106291     PISSN: 03032647     EISSN: 18728324     Source Type: Journal    
DOI: 10.1016/j.biosystems.2013.12.006     Document Type: Article

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