-
1
-
-
49749139694
-
Papillary glioneuronal tumor: A case report and review of the literature
-
18715860
-
Williams SR, Joos BW, Parker JC, Parker JR (2008) Papillary glioneuronal tumor: a case report and review of the literature. Ann Clin Lab Sci 38:287-292
-
(2008)
Ann Clin Lab Sci
, vol.38
, pp. 287-292
-
-
Williams, S.R.1
Joos, B.W.2
Parker, J.C.3
Parker, J.R.4
-
2
-
-
84872684798
-
TGF-beta as a therapeutic target in high grade gliomas: Promises and challenges
-
1:CAS:528:DC%2BC38XhslymsrvF 23159669 10.1016/j.bcp.2012.11.005
-
Joseph JV, Balasubramaniyan V, Walenkamp A, Kruyt FA (2013) TGF-beta as a therapeutic target in high grade gliomas: promises and challenges. Biochem Pharmacol 85:478-485
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 478-485
-
-
Joseph, J.V.1
Balasubramaniyan, V.2
Walenkamp, A.3
Kruyt, F.A.4
-
3
-
-
33645732219
-
Molecular pathology of malignant gliomas
-
1:CAS:528:DC%2BD28XktVOitbw%3D 18039109 10.1146/annurev.pathol.1.110304. 100043
-
Louis DN (2006) Molecular pathology of malignant gliomas. Annu Rev Pathol 1:97-117
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 97-117
-
-
Louis, D.N.1
-
4
-
-
54049108927
-
The 2007 World Health Organisation classification of tumours of the central nervous system, comparison with 2000 classification
-
1:STN:280:DC%2BD1cnjtVSguw%3D%3D 18819324
-
Rychly B, Sidlova H, Danis D (2008) The 2007 World Health Organisation classification of tumours of the central nervous system, comparison with 2000 classification. Cesk Patol 44:35-36
-
(2008)
Cesk Patol
, vol.44
, pp. 35-36
-
-
Rychly, B.1
Sidlova, H.2
Danis, D.3
-
5
-
-
84868023931
-
CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2005-2009
-
3480240 23095881 10.1093/neuonc/nos218
-
Dolecek TA, Propp JM, Stroup NE, Kruchko C (2012) CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009. Neuro Oncol 14(Suppl 5):v1-v49
-
(2012)
Neuro Oncol
, vol.14
, Issue.SUPPL. 5
-
-
Dolecek, T.A.1
Propp, J.M.2
Stroup, N.E.3
Kruchko, C.4
-
7
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
1929165 17618441 10.1007/s00401-007-0243-4
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A et al (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114:97-109
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
-
8
-
-
84855986523
-
Understanding the role of cytokines in glioblastoma multiforme pathogenesis
-
1:CAS:528:DC%2BC38XhtFajt7c%3D 22075379 10.1016/j.canlet.2011.11.001
-
Zhu VF, Yang J, Lebrun DG, Li M (2012) Understanding the role of cytokines in glioblastoma multiforme pathogenesis. Cancer Lett 316:139-150
-
(2012)
Cancer Lett
, vol.316
, pp. 139-150
-
-
Zhu, V.F.1
Yang, J.2
Lebrun, D.G.3
Li, M.4
-
9
-
-
0023700236
-
Grading of astrocytomas. A simple and reproducible method
-
1:STN:280:DyaL1M%2FivVSqtg%3D%3D 3179928 10.1002/1097-0142(19881115)62: 10<2152: AID-CNCR2820621015>3.0.CO;2-T
-
Daumas-Duport C, Scheithauer B, O'Fallon J, Kelly P (1988) Grading of astrocytomas. A simple and reproducible method. Cancer 62:2152-2165
-
(1988)
Cancer
, vol.62
, pp. 2152-2165
-
-
Daumas-Duport, C.1
Scheithauer, B.2
O'Fallon, J.3
Kelly, P.4
-
10
-
-
81855175346
-
Chemoattractant receptors as pharmacological targets for elimination of glioma stem-like cells
-
1:CAS:528:DC%2BC3MXhsFegtrfN 3224200 21930249 10.1016/j.intimp.2011.08. 021
-
Yao XH, Liu Y, Chen K, Gong W, Liu MY, Bian XW et al (2011) Chemoattractant receptors as pharmacological targets for elimination of glioma stem-like cells. Int Immunopharmacol 11:1961-1966
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 1961-1966
-
-
Yao, X.H.1
Liu, Y.2
Chen, K.3
Gong, W.4
Liu, M.Y.5
Bian, X.W.6
-
11
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
1:CAS:528:DC%2BC3cXovFCntro%3D 3491567 20639862 10.1038/nature09303
-
Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y (2010) Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466:1129-1133
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
12
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
1:CAS:528:DC%2BD1MXlslWnurY%3D 2715015 19372391 10.1126/science.1170116
-
Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y et al (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324:930-935
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
-
13
-
-
84867322151
-
5-Hydroxymethylcytosine the elusive epigenetic mark in mammalian DNA
-
1:CAS:528:DC%2BC38XhsVOnurfK 3467341 22842880 10.1039/c2cs35104h
-
Kriukiene E, Liutkeviciute Z, Klimasauskas S (2012) 5- Hydroxymethylcytosine the elusive epigenetic mark in mammalian DNA. Chem Soc Rev 41:6916-6930
-
(2012)
Chem Soc Rev
, vol.41
, pp. 6916-6930
-
-
Kriukiene, E.1
Liutkeviciute, Z.2
Klimasauskas, S.3
-
14
-
-
84860749868
-
Tet family proteins and 5-hydroxymethylcytosine in development and disease
-
1:CAS:528:DC%2BC38XhtVGlsLrL 22569552 10.1242/dev.070771
-
Tan L, Shi YG (2012) Tet family proteins and 5-hydroxymethylcytosine in development and disease. Development 139:1895-1902
-
(2012)
Development
, vol.139
, pp. 1895-1902
-
-
Tan, L.1
Shi, Y.G.2
-
15
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
1:CAS:528:DC%2BC3MXhtV2jt7nO 3462231 21817016 10.1126/science.1210944
-
He YF, Li BZ, Li Z, Liu P, Wang Y, Tang Q et al (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333:1303-1307
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
-
16
-
-
67649510355
-
Oxygenase catalyzed 5-methylcytosine hydroxylation
-
1:CAS:528:DC%2BD1MXnsFamtLY%3D 19549596 10.1016/j.chembiol.2009.06.002
-
Loenarz C, Schofield CJ (2009) Oxygenase catalyzed 5-methylcytosine hydroxylation. Chem Biol 16:580-583
-
(2009)
Chem Biol
, vol.16
, pp. 580-583
-
-
Loenarz, C.1
Schofield, C.J.2
-
17
-
-
79551635700
-
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1
-
1:CAS:528:DC%2BC3MXitVGiurY%3D 3032784 21311766 10.1371/journal.pone. 0016627
-
Frauer C, Rottach A, Meilinger D, Bultmann S, Fellinger K, Hasenoder S et al (2011) Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1. PLoS One 6:e16627
-
(2011)
PLoS One
, vol.6
, pp. 16627
-
-
Frauer, C.1
Rottach, A.2
Meilinger, D.3
Bultmann, S.4
Fellinger, K.5
Hasenoder, S.6
-
18
-
-
66749152204
-
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids
-
1:CAS:528:DC%2BD1MXptFehtb4%3D 2995806 19411852 10.4161/cc.8.11.8580
-
Iyer LM, Tahiliani M, Rao A, Aravind L (2009) Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell Cycle 8:1698-1710
-
(2009)
Cell Cycle
, vol.8
, pp. 1698-1710
-
-
Iyer, L.M.1
Tahiliani, M.2
Rao, A.3
Aravind, L.4
-
19
-
-
77449101855
-
Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia
-
1:CAS:528:DC%2BD1MXhsFGjsLzK 2908503 20010842 10.1038/nsmb.1714
-
Cierpicki T, Risner LE, Grembecka J, Lukasik SM, Popovic R, Omonkowska M et al (2010) Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia. Nat Struct Mol Biol 17:62-68
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 62-68
-
-
Cierpicki, T.1
Risner, L.E.2
Grembecka, J.3
Lukasik, S.M.4
Popovic, R.5
Omonkowska, M.6
-
20
-
-
79952053850
-
Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation
-
1:CAS:528:DC%2BC3MXit1eitrk%3D 21163962 10.1126/science.1195380
-
Song J, Rechkoblit O, Bestor TH, Patel DJ (2011) Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science 331:1036-1040
-
(2011)
Science
, vol.331
, pp. 1036-1040
-
-
Song, J.1
Rechkoblit, O.2
Bestor, T.H.3
Patel, D.J.4
-
21
-
-
79952473660
-
The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain
-
3072069 21407193 10.1038/ncomms1237
-
Xu C, Bian C, Lam R, Dong A, Min J (2011) The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun 2:227
-
(2011)
Nat Commun
, vol.2
, pp. 227
-
-
Xu, C.1
Bian, C.2
Lam, R.3
Dong, A.4
Min, J.5
-
22
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
-
1:CAS:528:DC%2BC3MXmsVChtLg%3D 3099128 21514197 10.1016/j.molcel.2011.04. 005
-
Xu Y, Wu F, Tan L, Kong L, Xiong L, Deng J et al (2011) Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol Cell 42:451-464
-
(2011)
Mol Cell
, vol.42
, pp. 451-464
-
-
Xu, Y.1
Wu, F.2
Tan, L.3
Kong, L.4
Xiong, L.5
Deng, J.6
-
23
-
-
78649825211
-
TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine
-
21079648 10.1038/cr.2010.156
-
Zhang H, Zhang X, Clark E, Mulcahey M, Huang S, Shi YG (2010) TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine. Cell Res 20:1390-1393
-
(2010)
Cell Res
, vol.20
, pp. 1390-1393
-
-
Zhang, H.1
Zhang, X.2
Clark, E.3
Mulcahey, M.4
Huang, S.5
Shi, Y.G.6
-
24
-
-
60149103624
-
Epigenetic mechanisms in mammals
-
1:CAS:528:DC%2BD1MXhvVOju70%3D 2780668 18985277 10.1007/s00018-008-8432-4
-
Kim JK, Samaranayake M, Pradhan S (2009) Epigenetic mechanisms in mammals. Cell Mol Life Sci 66:596-612
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 596-612
-
-
Kim, J.K.1
Samaranayake, M.2
Pradhan, S.3
-
25
-
-
74849086899
-
TET proteins in malignant hematopoiesis
-
1:CAS:528:DC%2BC3cXotlWru7Y%3D 19923888 10.4161/cc.8.24.10239
-
Langemeijer SM, Aslanyan MG, Jansen JH (2009) TET proteins in malignant hematopoiesis. Cell Cycle 8:4044-4048
-
(2009)
Cell Cycle
, vol.8
, pp. 4044-4048
-
-
Langemeijer, S.M.1
Aslanyan, M.G.2
Jansen, J.H.3
-
26
-
-
0034749352
-
Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein
-
1:CAS:528:DC%2BD3MXptVSm 88806 11113207 10.1128/MCB.21.1.330-342.2001
-
Hino S, Kishida S, Michiue T, Fukui A, Sakamoto I, Takada S et al (2001) Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein. Mol Cell Biol 21:330-342
-
(2001)
Mol Cell Biol
, vol.21
, pp. 330-342
-
-
Hino, S.1
Kishida, S.2
Michiue, T.3
Fukui, A.4
Sakamoto, I.5
Takada, S.6
-
27
-
-
58249097231
-
Decreased expression of CXXC4 promotes a malignant phenotype in renal cell carcinoma by activating Wnt signaling
-
1:CAS:528:DC%2BD1MXlsFKqtA%3D%3D 18931698 10.1038/onc.2008.391
-
Kojima T, Shimazui T, Hinotsu S, Joraku A, Oikawa T, Kawai K et al (2009) Decreased expression of CXXC4 promotes a malignant phenotype in renal cell carcinoma by activating Wnt signaling. Oncogene 28:297-305
-
(2009)
Oncogene
, vol.28
, pp. 297-305
-
-
Kojima, T.1
Shimazui, T.2
Hinotsu, S.3
Joraku, A.4
Oikawa, T.5
Kawai, K.6
-
28
-
-
31344466008
-
DNA methylation and gene silencing in cancer
-
1:CAS:528:DC%2BD28Xjs1Gisg%3D%3D 16341240 10.1038/ncponc0354
-
Baylin SB (2005) DNA methylation and gene silencing in cancer. Nat Clin Pract Oncol 2(Suppl 1):S4-S11
-
(2005)
Nat Clin Pract Oncol
, vol.2
, Issue.SUPPL. 1
-
-
Baylin, S.B.1
-
29
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
1:CAS:528:DC%2BD38XksFOmsrw%3D 12042769 10.1038/nrg962
-
Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3:415-428
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
30
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
1:CAS:528:DC%2BC3MXoslCks74%3D 3230223 21722948 10.1016/j.cell.2011.06. 020
-
Cortellino S, Xu J, Sannai M, Moore R, Caretti E, Cigliano A et al (2011) Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 146:67-79
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
Caretti, E.5
Cigliano, A.6
-
31
-
-
80054097425
-
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
-
1:CAS:528:DC%2BC3MXht1yksbbN 3799877 21940858 10.1126/science.1212483
-
Inoue A, Zhang Y (2011) Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 334:194
-
(2011)
Science
, vol.334
, pp. 194
-
-
Inoue, A.1
Zhang, Y.2
-
32
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
1:CAS:528:DC%2BC3MXhtV2jt7nN 3495246 21778364 10.1126/science.1210597
-
Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA et al (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333:1300-1303
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
Wu, S.C.4
Collins, L.B.5
Swenberg, J.A.6
-
33
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
1:CAS:528:DC%2BC3MXlsFShsrs%3D 3088758 21496894 10.1016/j.cell.2011.03. 022
-
Guo JU, Su Y, Zhong C, Ming GL, Song H (2011) Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145:423-434
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
34
-
-
77956095231
-
Active DNA demethylation: Many roads lead to Rome
-
1:CAS:528:DC%2BC3cXps1egtbY%3D 3711520 20683471 10.1038/nrm2950
-
Wu SC, Zhang Y (2010) Active DNA demethylation: many roads lead to Rome. Nat Rev Mol Cell Biol 11:607-620
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 607-620
-
-
Wu, S.C.1
Zhang, Y.2
-
35
-
-
84874766461
-
Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
-
1:CAS:528:DC%2BC3sXjtlKqsrg%3D 23316048 10.1074/jbc.M112.431098
-
Otani J, Arita K, Kato T, Kinoshita M, Kimura H, Suetake I et al (2013) Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4. J Biol Chem 288:6351-6362
-
(2013)
J Biol Chem
, vol.288
, pp. 6351-6362
-
-
Otani, J.1
Arita, K.2
Kato, T.3
Kinoshita, M.4
Kimura, H.5
Suetake, I.6
-
36
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
1:CAS:528:DC%2BC3MXkslCmsLo%3D 3408592 21490601 10.1038/nature10066
-
Williams K, Christensen J, Pedersen MT, Johansen JV, Cloos PA, Rappsilber J et al (2011) TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473:343-348
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
Johansen, J.V.4
Cloos, P.A.5
Rappsilber, J.6
-
37
-
-
82955207588
-
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
-
1:CAS:528:DC%2BC3MXhs1GqtLfN 22156206 10.1101/gad.179184.111
-
Wu H, Zhang Y (2011) Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev 25:2436-2452
-
(2011)
Genes Dev
, vol.25
, pp. 2436-2452
-
-
Wu, H.1
Zhang, Y.2
-
38
-
-
79956292024
-
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
-
1:CAS:528:DC%2BC3MXjvFOnt7s%3D 3539771 21451524 10.1038/nature09934
-
Wu H, D'Alessio AC, Ito S, Xia K, Wang Z, Cui K et al (2011) Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 473:389-393
-
(2011)
Nature
, vol.473
, pp. 389-393
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Xia, K.4
Wang, Z.5
Cui, K.6
-
39
-
-
79954457998
-
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
-
1:CAS:528:DC%2BC3MXkvFCrtb8%3D 21460036 10.1101/gad.2036011
-
Wu H, D'Alessio AC, Ito S, Wang Z, Cui K, Zhao K et al (2011) Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev 25:679-684
-
(2011)
Genes Dev
, vol.25
, pp. 679-684
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Wang, Z.4
Cui, K.5
Zhao, K.6
-
40
-
-
0030959555
-
Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats
-
1:CAS:528:DyaK2sXisVGqs7s%3D 9083067 10.1074/jbc.272.14.9308
-
Kreppel LK, Blomberg MA, Hart GW (1997) Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats. J Biol Chem 272:9308-9315
-
(1997)
J Biol Chem
, vol.272
, pp. 9308-9315
-
-
Kreppel, L.K.1
Blomberg, M.A.2
Hart, G.W.3
-
41
-
-
84880530231
-
Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells
-
1:CAS:528:DC%2BC3sXhtFeksL3N 23729667 10.1074/jbc.M113.460386
-
Shi FT, Kim H, Lu W, He Q, Liu D, Goodell MA et al (2013) Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells. J Biol Chem 288:20776-20784
-
(2013)
J Biol Chem
, vol.288
, pp. 20776-20784
-
-
Shi, F.T.1
Kim, H.2
Lu, W.3
He, Q.4
Liu, D.5
Goodell, M.A.6
-
42
-
-
84874266225
-
Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells
-
1:CAS:528:DC%2BC3sXhsFGjsb8%3D 23352454 10.1016/j.molcel.2012.12.019
-
Vella P, Scelfo A, Jammula S, Chiacchiera F, Williams K, Cuomo A et al (2013) Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells. Mol Cell 49:645-656
-
(2013)
Mol Cell
, vol.49
, pp. 645-656
-
-
Vella, P.1
Scelfo, A.2
Jammula, S.3
Chiacchiera, F.4
Williams, K.5
Cuomo, A.6
-
43
-
-
84860378636
-
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity
-
1:CAS:528:DC%2BC38Xmt1yqt7o%3D 3333871 22210859 10.1093/nar/gkr1253
-
Freudenberg JM, Ghosh S, Lackford BL, Yellaboina S, Zheng X, Li R et al (2012) Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity. Nucleic Acids Res 40:3364-3377
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 3364-3377
-
-
Freudenberg, J.M.1
Ghosh, S.2
Lackford, B.L.3
Yellaboina, S.4
Zheng, X.5
Li, R.6
-
44
-
-
84875218124
-
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
-
1:CAS:528:DC%2BC3sXhsVaqu7o%3D 23353889 10.1038/emboj.2012.357
-
Deplus R, Delatte B, Schwinn MK, Defrance M, Mendez J, Murphy N et al (2013) TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. EMBO J 32:645-655
-
(2013)
EMBO J
, vol.32
, pp. 645-655
-
-
Deplus, R.1
Delatte, B.2
Schwinn, M.K.3
Defrance, M.4
Mendez, J.5
Murphy, N.6
-
45
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
1:CAS:528:DC%2BD3sXhsV2kt7s%3D 12610534 10.1038/ng1089
-
Jaenisch R, Bird A (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 33(Suppl):245-254
-
(2003)
Nat Genet
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
46
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
1:CAS:528:DC%2BD1cXhtFCrtLrE 2820389 18772396 10.1126/science.1164382
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P et al (2008) An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-1812
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
-
47
-
-
65649121938
-
Glioblastoma multiforme oncogenomics and signaling pathways
-
2748278 19777070
-
Kanu OO, Hughes B, Di C, Lin N, Fu J, Bigner DD et al (2009) Glioblastoma multiforme oncogenomics and signaling pathways. Clin Med Oncol 3:39-52
-
(2009)
Clin Med Oncol
, vol.3
, pp. 39-52
-
-
Kanu, O.O.1
Hughes, B.2
Di, C.3
Lin, N.4
Fu, J.5
Bigner, D.D.6
-
48
-
-
81855213133
-
Isocitrate dehydrogenase mutations in gliomas: Mechanisms, biomarkers and therapeutic target
-
3640434 22002076 10.1097/WCO.0b013e32834cd415
-
Guo C, Pirozzi CJ, Lopez GY, Yan H (2011) Isocitrate dehydrogenase mutations in gliomas: mechanisms, biomarkers and therapeutic target. Curr Opin Neurol 24:648-652
-
(2011)
Curr Opin Neurol
, vol.24
, pp. 648-652
-
-
Guo, C.1
Pirozzi, C.J.2
Lopez, G.Y.3
Yan, H.4
-
49
-
-
78649990315
-
Cancer-associated IDH mutations: Biomarker and therapeutic opportunities
-
1:CAS:528:DC%2BC3cXhtlahu7vO 20972461 10.1038/onc.2010.444
-
Yen KE, Bittinger MA, Su SM, Fantin VR (2010) Cancer-associated IDH mutations: biomarker and therapeutic opportunities. Oncogene 29:6409-6417
-
(2010)
Oncogene
, vol.29
, pp. 6409-6417
-
-
Yen, K.E.1
Bittinger, M.A.2
Su, S.M.3
Fantin, V.R.4
-
50
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases
-
1:CAS:528:DC%2BC3MXpvValsQ%3D%3D 3229304 21251613 10.1016/j.ccr.2010.12. 014
-
Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH et al (2011) Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases. Cancer Cell 19:17-30
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
Yang, Y.4
Wang, P.5
Kim, S.H.6
-
51
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
1:CAS:528:DC%2BC3cXhsFGhsbvJ 21130701 10.1016/j.ccr.2010.11.015
-
Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A et al (2010) Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18:553-567
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
Ward, P.S.4
Patel, J.5
Shih, A.6
-
52
-
-
84885848576
-
Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2
-
3759038 23863747 10.1038/ncomms3166
-
Guilhamon P, Eskandarpour M, Halai D, Wilson GA, Feber A, Teschendorff AE et al (2013) Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2. Nat Commun 4:2166
-
(2013)
Nat Commun
, vol.4
, pp. 2166
-
-
Guilhamon, P.1
Eskandarpour, M.2
Halai, D.3
Wilson, G.A.4
Feber, A.5
Teschendorff, A.E.6
-
53
-
-
67650924270
-
Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML
-
1:CAS:528:DC%2BD1MXoslOhs7w%3D 19295549 10.1038/leu.2009.59
-
Tefferi A, Lim KH, Abdel-Wahab O, Lasho TL, Patel J, Patnaik MM et al (2009) Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML. Leukemia 23:1343-1345
-
(2009)
Leukemia
, vol.23
, pp. 1343-1345
-
-
Tefferi, A.1
Lim, K.H.2
Abdel-Wahab, O.3
Lasho, T.L.4
Patel, J.5
Patnaik, M.M.6
-
54
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
10.1038/4551040a
-
Parsons DW, Jones S, Zhang X et al (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-1068
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
55
-
-
84862776918
-
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
-
1:CAS:528:DC%2BC38XisVKktb4%3D 3656605 22343896 10.1038/nature10898
-
Koivunen P, Lee S, Duncan CG, Lopez G, Lu G, Ramkissoon S et al (2012) Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature 483:484-488
-
(2012)
Nature
, vol.483
, pp. 484-488
-
-
Koivunen, P.1
Lee, S.2
Duncan, C.G.3
Lopez, G.4
Lu, G.5
Ramkissoon, S.6
-
56
-
-
80053215336
-
TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations
-
1:CAS:528:DC%2BC38XhsFCnsbg%3D 21690245 10.1136/jclinpath-2011-200133
-
Kim YH, Pierscianek D, Mittelbronn M, Vital A, Mariani L, Hasselblatt M et al (2011) TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations. J Clin Pathol 64:850-852
-
(2011)
J Clin Pathol
, vol.64
, pp. 850-852
-
-
Kim, Y.H.1
Pierscianek, D.2
Mittelbronn, M.3
Vital, A.4
Mariani, L.5
Hasselblatt, M.6
-
57
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
1:CAS:528:DC%2BC3cXhtl2jtrrP 3003755 21057493 10.1038/nature09586
-
Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS et al (2010) Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 468:839-843
-
(2010)
Nature
, vol.468
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
Pape, U.J.4
Tahiliani, M.5
Bandukwala, H.S.6
-
58
-
-
80054046273
-
Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia
-
1:CAS:528:DC%2BC3MXhtlajurvL 21625234 10.1038/leu.2011.134
-
Konstandin N, Bultmann S, Szwagierczak A, Dufour A, Ksienzyk B, Schneider F et al (2011) Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia. Leukemia 25:1649-1652
-
(2011)
Leukemia
, vol.25
, pp. 1649-1652
-
-
Konstandin, N.1
Bultmann, S.2
Szwagierczak, A.3
Dufour, A.4
Ksienzyk, B.5
Schneider, F.6
-
59
-
-
84864120277
-
Nuclear exclusion of TET1 is associated with loss of 5- hydroxymethylcytosine in IDH1 wild-type gliomas
-
22688054 10.1016/j.ajpath.2012.04.017
-
Muller T, Gessi M, Waha A, Isselstein LJ, Luxen D, Freihoff D et al (2012) Nuclear exclusion of TET1 is associated with loss of 5- hydroxymethylcytosine in IDH1 wild-type gliomas. Am J Pathol 181:675-683
-
(2012)
Am J Pathol
, vol.181
, pp. 675-683
-
-
Muller, T.1
Gessi, M.2
Waha, A.3
Isselstein, L.J.4
Luxen, D.5
Freihoff, D.6
-
60
-
-
84864053192
-
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma
-
1:CAS:528:DC%2BC38XhtFSksLbM 3400598 22829908 10.1371/journal.pone. 0041036
-
Orr BA, Haffner MC, Nelson WG, Yegnasubramanian S, Eberhart CG (2012) Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. PLoS One 7:e41036
-
(2012)
PLoS One
, vol.7
, pp. 41036
-
-
Orr, B.A.1
Haffner, M.C.2
Nelson, W.G.3
Yegnasubramanian, S.4
Eberhart, C.G.5
-
61
-
-
79960626636
-
The discovery of 5-formylcytosine in embryonic stem cell DNA
-
1:CAS:528:DC%2BC3MXotFygtbs%3D 21721093 10.1002/anie.201103899
-
Pfaffeneder T, Hackner B, Truss M, Munzel M, Muller M, Deiml CA et al (2011) The discovery of 5-formylcytosine in embryonic stem cell DNA. Angew Chem Int Ed Engl 50:7008-7012
-
(2011)
Angew Chem Int Ed Engl
, vol.50
, pp. 7008-7012
-
-
Pfaffeneder, T.1
Hackner, B.2
Truss, M.3
Munzel, M.4
Muller, M.5
Deiml, C.A.6
-
62
-
-
84255200412
-
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations
-
1:CAS:528:DC%2BC3MXhs1agtr3M 3242933 22052461 10.1158/0008-5472.CAN-11- 2023
-
Jin SG, Jiang Y, Qiu R, Rauch TA, Wang Y, Schackert G et al (2011) 5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer Res 71:7360-7365
-
(2011)
Cancer Res
, vol.71
, pp. 7360-7365
-
-
Jin, S.G.1
Jiang, Y.2
Qiu, R.3
Rauch, T.A.4
Wang, Y.5
Schackert, G.6
-
63
-
-
84864463122
-
Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base", are associated with anaplasia in human brain tumors
-
1:CAS:528:DC%2BC38XjtFOltrs%3D 22234893 10.1002/ijc.27429
-
Kraus TF, Globisch D, Wagner M, Eigenbrod S, Widmann D, Munzel M et al (2012) Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base", are associated with anaplasia in human brain tumors. Int J Cancer 131:1577-1590
-
(2012)
Int J Cancer
, vol.131
, pp. 1577-1590
-
-
Kraus, T.F.1
Globisch, D.2
Wagner, M.3
Eigenbrod, S.4
Widmann, D.5
Munzel, M.6
-
65
-
-
79952111851
-
DNA methylation and cancer
-
1:CAS:528:DC%2BC3cXhsFOns7bE 21141722
-
Taberlay PC, Jones PA (2011) DNA methylation and cancer. Prog Drug Res 67:1-23
-
(2011)
Prog Drug Res
, vol.67
, pp. 1-23
-
-
Taberlay, P.C.1
Jones, P.A.2
-
66
-
-
84866908544
-
TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases
-
1:CAS:528:DC%2BC38XhsFSmsLzL 22999938 10.1016/j.celrep.2012.08.030
-
Hsu CH, Peng KL, Kang ML, Chen YR, Yang YC, Tsai CH et al (2012) TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases. Cell Rep 2:568-579
-
(2012)
Cell Rep
, vol.2
, pp. 568-579
-
-
Hsu, C.H.1
Peng, K.L.2
Kang, M.L.3
Chen, Y.R.4
Yang, Y.C.5
Tsai, C.H.6
-
67
-
-
84873411803
-
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation
-
1:CAS:528:DC%2BC38XjtlOrtbc%3D 3897214 22391558 10.1038/onc.2012.67
-
Yang H, Liu Y, Bai F, Zhang JY, Ma SH, Liu J et al (2013) Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene 32:663-669
-
(2013)
Oncogene
, vol.32
, pp. 663-669
-
-
Yang, H.1
Liu, Y.2
Bai, F.3
Zhang, J.Y.4
Ma, S.H.5
Liu, J.6
-
68
-
-
84862298845
-
Reduction of DNA hydroxymethylation in the mouse kidney insulted by ischemia reperfusion
-
1:CAS:528:DC%2BC38XotVeltLg%3D 22627137 10.1016/j.bbrc.2012.05.061
-
Huang N, Tan L, Xue Z, Cang J, Wang H (2012) Reduction of DNA hydroxymethylation in the mouse kidney insulted by ischemia reperfusion. Biochem Biophys Res Commun 422:697-702
-
(2012)
Biochem Biophys Res Commun
, vol.422
, pp. 697-702
-
-
Huang, N.1
Tan, L.2
Xue, Z.3
Cang, J.4
Wang, H.5
-
69
-
-
20844459387
-
A microarray study to characterize the molecular mechanism of TIMP-3-mediated tumor rejection
-
1:CAS:528:DC%2BD2MXlt1Glsrg%3D 15963930 10.1016/j.ymthe.2005.02.028
-
Lam P, Sian Lim K, Mei Wang S, Hui KM (2005) A microarray study to characterize the molecular mechanism of TIMP-3-mediated tumor rejection. Mol Ther 12:144-152
-
(2005)
Mol Ther
, vol.12
, pp. 144-152
-
-
Lam, P.1
Sian Lim, K.2
Mei Wang, S.3
Hui, K.M.4
-
70
-
-
34247501352
-
Frequent but borderline methylation of p16 (INK4a) and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses
-
1:STN:280:DC%2BD2s3pvFWrsQ%3D%3D 17206475 10.1007/s11060-006-9309-8
-
Muhlisch J, Bajanowski T, Rickert CH, Roggendorf W, Wurthwein G, Jurgens H et al (2007) Frequent but borderline methylation of p16 (INK4a) and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses. J Neurooncol 83:17-29
-
(2007)
J Neurooncol
, vol.83
, pp. 17-29
-
-
Muhlisch, J.1
Bajanowski, T.2
Rickert, C.H.3
Roggendorf, W.4
Wurthwein, G.5
Jurgens, H.6
|