Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4

Journal of Biological Chemistry

Volumn 288, Issue 9, 2013, Pages 6351-6362

  Otani, Junji ^a   Arita, Kyohei ^a   Kato, Tsuyoshi ^a   Kinoshita, Mariko ^a   Kimura, Hironobu ^b   Suetake, Isao ^b   Tajima, Shoji ^b   Ariyoshi, Mariko ^c,d   Shirakawa, Masahiro ^a,d,e  

^a KYOTO UNIVERSITY   (Japan)

^b BIOMOL ENG RESEARCH INSTITUTE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e RIKEN YOKOHAMA INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5-HYDROXYMETHYLCYTOSINE; BINDING DOMAIN; BIOCHEMICAL ANALYSIS; DINUCLEOTIDES; DNA DEMETHYLATION; DNA METHYLATION PATTERN; DNA RECOGNITION; GLYCOSYLASE; MBD PROTEIN; RECOGNITION ABILITIES; STRUCTURAL BASIS; STRUCTURAL FEATURE; TRANSCRIPTIONAL REPRESSION; WATER NETWORKS;

AMINES; BELT DRIVES; DNA; PROTEINS;

BINDING SITES;

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; CPG DINUCLEOTIDE; DINUCLEOTIDE; DNA; METHYL CPG BINDING PROTEIN; METHYL CPG BINDING PROTEIN 4; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEAMINATION; DNA METHYLATION; GENETIC REGULATION; MOLECULAR RECOGNITION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN STRUCTURE;

5-METHYLCYTOSINE; ANIMALS; CRYSTALLOGRAPHY, X-RAY; CYTOSINE; DNA METHYLATION; ENDODEOXYRIBONUCLEASES; HUMANS; MICE; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84874766461     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.431098     Document Type: Article

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